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Protein Overview: ISPE_PSEAE

General Information:
Name(s) found: ISPE_PSEAE [Swiss-Prot]
Description(s) found:
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  • gi|12230905|sp|P42805.2|ISPE_PSEAE RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [NCBI NR]
  • pir||F83063 isopentenyl monophosphate kinase PA4669 [imported] - Pseudomonas aeruginosa (strain PAO1) [NCBI NR]
  • 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Pseudomonas aeruginosa GN=ispE PE=3 SV=2 [Swiss-Prot]
  • isopentenyl monophosphate kinase [Pseudomonas aeruginosa PAO1]gi|9950924|gb|AAG08056.1| isopentenyl monophosphate kinase [Pseudomonas aeruginosa PAO1]gi|11350527|pir||F83063 isopentenyl monophosphate kinase PA4669 [imported] - Pseudomonas aeruginosa (st [nrdb_11152004_Chlamydomonas]
  • 2|isopentenyl monophosphate kinase [P_aeruginosa_combined.faa]
  • 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) [nr-271106-contam.fasta]
  • 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=ispE PE=3 SV=2 [uniprot-Pseudomonas_aeruginosa.fasta]
    • Organism: Pseudomonas aeruginosa
    Length: 282 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRLSLPAP AKLNLFLHIL GRRDDGYHEL QTLFQFLDHG DELHFEARQD GQVRLHTEIA  60
   61 GVPHDSNLIV RAARGLQEAS GSPQGVDIWL DKRLPMGGGI GGGSSDAATT LLALNHLWQL 120
  121 GWDEDRIAAL GLRLGADVPV FTRGRAAFAE GVGEKLTPVD IPEPWYLVVV PQVLVSTAEI 180
  181 FSDPLLTRDS PAIKVRTVLE GDSRNDCQPV VERRYPEVRN ALILLNKFVS ARLTGTGGCV 240
  241 FGSFPNKAEA DKVSALLPDH LQRFVAKGSN ISMLHRKLET LV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..282] PSI-BLAST 67.39794 Ternary complex of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
    		•  1.9881460462076 bayes_pls_golite062009
  • catalytic activity
    		•  1.20658247466773 bayes_pls_golite062009
  • diphosphomevalonate decarboxylase activity
    		•  1.0502744466494 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle