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Protein Overview: PLPP1_MOUSE

General Information:
Name(s) found: PLPP1_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|6679431|ref|NP_032929.1| phosphatidic acid phosphatase type 2A isoform 2 [Mus musculus] [NCBI NR]
  • gi|45477086|sp|Q61469.1|LPP1_MOUSE RecName: Full=Lipid phosphate phosphohydrolase 1; AltName: Full=Phosphatidic acid phosphatase 2a; AltName: Full=PAP2-alpha; Short=PAP-2a; Short=PAP2a; AltName: Full=Phosphatidate phosphohydrolase type 2a; AltName: Full=H [NCBI NR]
  • gi|30038763|gb|AAP04434.1| lipid phosphate phosphatase 1 [Mus musculus] [NCBI NR]
  • gi|1487873|dbj|BAA12335.1| Phosphatidic acid phosphatase [Mus musculus] [NCBI NR]
  • gi|148686458|gb|EDL18405.1| phosphatidic acid phosphatase 2a, isoform CRA_a [Mus musculus] [NCBI NR]
  • Phospholipid phosphatase 1 OS=Mus musculus GN=Plpp1 PE=1 SV=1 [Swiss-Prot]
  • Lipid phosphate phosphohydrolase 1 OS=Mus musculus GN=Ppap2a PE=1 SV=1 [Swiss-Prot]
  • phosphatidic acid phosphatase 2a; lipid phosphate phosphatase 1; hydrogen peroxide inducible protein 53 [HMR_022704-rand.fasta]
  • Splice Isoform 1 of Lipid phosphate phosphohydrolase 1 [ipi.MOUSE.v3.06.fasta]
  • phosphatidic acid phosphatase 2a [Mus musculus]gi|30038763|gb|AAP04434.1| lipid phosphate phosphatase 1 [Mus musculus]gi|45477086|sp|Q61469|LPP1_MOUSE Lipid phosphate phosphohydrolase 1 (Phosphatidic acid phosphatase 2a) (Phosphatidate phosphohydrolase [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Splice Isoform 1 of Lipid phosphate phosphohydrolase 1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_008903) phosphatidic acid phosphatase 2a; Lipid phosphate phosphatase 1 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • phosphatidic acid phosphatase 2a isoform 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Lipid phosphate phosphohydrolase 1 (Phosphatidic acid phosphatase 2a) (PAP2-alpha) (PAP-2a) (PAP2a) (Phosphatidate phosphohydrolase type 2a) (Hydrogen peroxide-inducible protein 53) (Hic53) (35 kDa PAP) (mPAP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • phosphatidic acid phosphatase 2a, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • lipid phosphate phosphatase 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Phosphatidic acid phosphatase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • phosphatidic acid phosphatase type 2A isoform 2 [Mus musculus] [NCBI-RefSeq_mouse_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Ppap2a Isoform 1 of Lipid phosphate phosphohydrolase 1 [mouse-ipi-250309-contam.fasta]
  • Lipid phosphate phosphohydrolase 1 (Phosphatidic acid phosphatase 2a) (Phosphatidate phosphohydrolase type 2a) (PAP2a) (PAP-2a) (PAP2-alpha) (Hydrogen peroxide-inducible protein 53) (Hic53) (35 kDa PAP) (mPAP) [nr-271106-contam.fasta]
  • lipid phosphate phosphohydrolase 1 isoform 2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00407419.2|SWISS-PROT:Q61469-1|TREMBL:Q80XY1|ENSEMBL:ENSMUSP00000064423|REFSEQ:NP_032929 Tax_Id=10090 Gene_Symbol=Ppap2a Isoform 1 of Lipid phosphate phosphohydrolase 1 [ipi.MOUSE.fasta.20090209]
  • Isoform 1 of Lipid phosphate phosphohydrolase 1 OS=Mus musculus GN=Ppap2a [011711_HMR.fasta]
  • sp|Q61469|LPP1_MOUSE Lipid phosphate phosphohydrolase 1 OS=Mus musculus GN=Ppap2a PE=1 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 283 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [TAS]
    membrane [IEA]
    integral to membrane [IEA]
    plasma membrane [TAS]
    Biological Process: signal transduction [TAS]
    sphingosine metabolic process [TAS]
    protein amino acid dephosphorylation [IDA][TAS]
    diacylglycerol biosynthetic process [TAS]
    ceramide metabolic process [TAS]
    Molecular Function: phosphatidate phosphatase activity [IDA][ISS][TAS]
    catalytic activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDKTRLPYV ALDVICVLLA GLPFAILTSR HTPFQRGIFC NDDSIKYPYK EDTIPYALLG  60
   61 GIVIPFCIIV MSIGESLSVY FNVLHSNSFV GNPYIATIYK AVGAFLFGVS ASQSLTDIAK 120
  121 YTIGSLRPHF LAICNPDWSK INCSDGYIED YICQGNEEKV KEGRLSFYSG HSSFSMYCML 180
  181 FVALYLQARM KGDWARLLRP MLQFGLIAFS IYVGLSRVSD YKHHWSDVTV GLIQGAAMAI 240
  241 LVALYVSDFF KDTHSYKERK EEDPHTTLHE TASSRNYSTN HEP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] MSA 2.560996 View MSA. No confident structure predictions are available.
    2 View Details [89..283] PSI-BLAST 12.522879 No description for 2akcA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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