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Protein Overview: RPOD_ECOLI

General Information:
Name(s) found: RPOD_ECOLI [Swiss-Prot]
Description(s) found:
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  • gi|882590|gb|AAA89147.1| CG Site No. 231; alternate gene name alt [NCBI NR]
  • pir||RNECS transcription initiation factor sigma 70 - Escherichia coli (strain K-12) [NCBI NR]
  • gi|73671318|gb|AAZ80070.1| RpoD [Escherichia coli] [NCBI NR]
  • gi|1710680|sp|P00579.2|RPOD_ECOLI RecName: Full=RNA polymerase sigma factor rpoD; AltName: Full=Sigma-70 [NCBI NR]
  • RNA polymerase sigma factor rpoD (Sigma-70) - Escherichia coli [Swiss-Prot]
  • RNA polymerase, sigma(70) factor; regulation of proteins induced at high temperatures; sigma D (sigma 70) factor of RNA polymerase [Escherichia coli K12]gi|1789448|gb|AAC76103.1| RNA polymerase, sigma(70) factor; regulation of proteins induced at high te [nrdb_11152004_Chlamydomonas]
  • RNA polymerase sigma factor rpoD (Sigma-70) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • RNA polymerase sigma factor rpoD OS=Escherichia coli (strain K12) GN=rpoD PE=1 SV=2 [uniprot-Ecoli-reviewed-110511.fasta]
  • RNA polymerase sigma factor RpoD OS=Escherichia coli (strain K12) GN=rpoD PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Escherichia coli
    Length: 613 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQNPQSQLK LLVTRGKEQG YLTYAEVNDH LPEDIVDSDQ IEDIIQMIND MGIQVMEEAP  60
   61 DADDLMLAEN TADEDAAEAA AQVLSSVESE IGRTTDPVRM YMREMGTVEL LTREGEIDIA 120
  121 KRIEDGINQV QCSVAEYPEA ITYLLEQYDR VEAEEARLSD LITGFVDPNA EEDLAPTATH 180
  181 VGSELSQEDL DDDEDEDEED GDDDSADDDN SIDPELAREK FAELRAQYVV TRDTIKAKGR 240
  241 SHATAQEEIL KLSEVFKQFR LVPKQFDYLV NSMRVMMDRV RTQERLIMKL CVEQCKMPKK 300
  301 NFITLFTGNE TSDTWFNAAI AMNKPWSEKL HDVSEEVHRA LQKLQQIEEE TGLTIEQVKD 360
  361 INRRMSIGEA KARRAKKEMV EANLRLVISI AKKYTNRGLQ FLDLIQEGNI GLMKAVDKFE 420
  421 YRRGYKFSTY ATWWIRQAIT RSIADQARTI RIPVHMIETI NKLNRISRQM LQEMGREPTP 480
  481 EELAERMLMP EDKIRKVLKI AKEPISMETP IGDDEDSHLG DFIEDTTLEL PLDSATTESL 540
  541 RAATHDVLAG LTAREAKVLR MRFGIDMNTD YTLEEVGKQF DVTRERIRQI EAKALRKLRH 600
  601 PSRSEVLRSF LDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] FFAS03 2.9 DNA-directed RNA polymerase alpha(2), beta, beta-prime and omega subunits
    2 View Details [110..240] PSI-BLAST 67.69897 CRYSTAL STRUCTURE OF A SIGMA70 SUBUNIT FRAGMENT FROM ESCHERICHIA COLI RNA POLYMERASE
    3 View Details [241..613] PSI-BLAST 67.09691 Sigma70

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription initiation factor activity
    		•  5.71806750193815 bayes_pls_golite062009
  • sigma factor activity
    		•  5.58029806879061 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.67872017549582 bayes_pls_golite062009
  • binding
    		•  1.02634976114785 bayes_pls_golite062009
    3
    Term Confidence Notes
  • transcription initiation factor activity
    		•  5.78609205758337 bayes_pls_golite062009
  • sigma factor activity
    		•  5.64833683794078 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.74356768143558 bayes_pls_golite062009
  • binding
    		•  1.07192234179226 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle