Protein Overview: SMAD5_DANRE

General Information:
Name(s) found:	SMAD5_DANRE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6288777\|gb\|AAF06738.1\| Smad5 protein [Danio rerio] [NCBI NR] gi\|5478498\|gb\|AAD43904.1\|AF127920_1 mad-related protein Smad5 [Danio rerio] [NCBI NR] gi\|41351191\|gb\|AAH65644.1\| MAD homolog 5 (Drosophila) [Danio rerio] [NCBI NR] gi\|21264062\|sp\|Q9W7E7.1\|SMAD5_DANRE RecName: Full=Mothers against decapentaplegic homolog 5; Short=Mothers against DPP homolog 5; AltName: Full=SMAD 5; Short=Smad5; AltName: Full=Protein somitabun [NCBI NR] gi\|161611484\|gb\|AAI55777.1\| Smad5 protein [Danio rerio] [NCBI NR] gi\|158254340\|gb\|AAI54312.1\| MAD homolog 5 (Drosophila) [Danio rerio] [NCBI NR] gi\|148725434\|emb\|CAN88456.1\| MAD homolog 5 (Drosophila) [Danio rerio] [NCBI NR] Mothers against decapentaplegic homolog 5 OS=Danio rerio GN=smad5 PE=2 SV=1 [Swiss-Prot] Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (Somitabun protein) - Brachydanio rerio (Zebrafish) (Danio rerio) [Swiss-Prot] (Q9W7E7) Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (Somitabun protein) [Swiss-Prot] MAD homolog 5 [Danio rerio]gi\|6288777\|gb\|AAF06738.1\| Smad5 protein [Danio rerio]gi\|5478498\|gb\|AAD43904.1\| mad-related protein Smad5 [Danio rerio]gi\|21264062\|sp\|Q9W7E7\|SMA5_BRARE Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP ho [nrdb_11152004_Chlamydomonas] Smad5 protein [Danio rerio] [nr-271106-contam.fasta] Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (Somitabun protein) [nr-271106-contam.fasta] mad-related protein Smad5 [Danio rerio] [nr-271106-contam.fasta] MAD homolog 5 (Drosophila) [Danio rerio] [nr-271106-contam.fasta] RecName: Full=Mothers against decapentaplegic homolog 5; Short=MAD homolog 5; Short=Mothers against DPP homolog 5; AltName: Full=Protein somitabun; AltName: Full=SMAD family member 5; Short=SMAD 5; Short=Smad5 [NCBI_RefSeq_D_rerio_20120531_05-31-2012_reversed.fasta] Isoform of Q9W7E7, Mothers against decapentaplegic homolog OS=Danio rerio GN=smad5 PE=1 SV=1 [DANRE.fasta.20160308]
Organism:	Danio rerio
Length:	464 amino acids
Gene Ontology:
Cellular Component:	transcription factor complex [IEA] nucleus [IEA] cytoplasm [IEA] intracellular [IEA]
Biological Process:	transcription [IEA] dorsal convergence [IMP] multicellular organismal development [IEA] embryonic pattern specification [IMP] transforming growth factor beta receptor signaling pathway [IEA] regulation of transcription, DNA-dependent [IEA][NAS] blood vessel morphogenesis [IGI] embryonic heart tube morphogenesis [IMP] regulation of transcription [IEA] otic placode formation [IEP] heart jogging [IMP] determination of left/right symmetry [IMP] dorsal/ventral pattern formation [IGI][IMP] determination of ventral identity [IDA][IGI][IMP] determination of dorsal/ventral asymmetry [IGI] BMP signaling pathway [IGI][IMP] heart looping [IMP]
Molecular Function:	transcription factor activity [IEA][NAS] protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSMSSLFSF TSPAVKRLLG WKQGDEEEKW AEKAVDALVK KLKKKKGAME DLEKALSSPG  60
   61 QPSKCVTIPR SLDGRLQVSH RKGLPHVIYC RVWRWPDLQS HHELKPLEVC EYPFGSKQKE 120
  121 VCINPYHYKR VESPVLPPVL VPRHSEFNPQ HSLLVQFRNL SHNEPHMPLN ATFPESFQQH 180
  181 SGGSSFPISP NSPYPPSPAS SGTYPNSPAS SGPSSPFQLP ADTPPPAYMP PDEQMGQDGS 240
  241 QSMETGSSLA PQNMPRGDVQ PVEYQEPSHW CSIVYYELNN RVGEAYHASS TSVLVDGFTD 300
  301 PSNNKNRFCL GLLSNVNRNS TIENTRRHIG KGVHLYYVGG EVYAECLSDT SIFVQSRNCN 360
  361 YHHGFHPTTV CKIPSGCSLK IFNNQEFAQL LAQSVNHGFE AVYELTKMCT IRMSFVKGWG 420
  421 AEYHRQDVTS TPCWIEVHLH GPLQWLDKVL TQMGSPLNPI SSVS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.60

Protein Overview: SMAD5_DANRE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: