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Protein Overview: wapl-PB

General Information:
Name(s) found: wapl-PB / FBpp0070414 [FlyBase]
Description(s) found:
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  • gi|45551388|ref|NP_726796.2| wings apart-like, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45446784|gb|AAF45735.2| wings apart-like, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene wings apart-like is referred to in FlyBase by the symbol Dmel\wapl (CG3707, FBgn0004655). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2044135..2053016. It has the cytological map location 2D4-2D5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; sister chromatid cohesion. 37 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing; tergite; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • (AAF45735) CG3707-PB [DrosMelano7227.FASTAC.txt]
  • CG3707-PB, isoform B [Drosophila melanogaster]gi|45551388|ref|NP_726796.2| CG3707-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(2044910..2045185,2045305..2045495,2045556..2045644,2045710..2045879,2045950..2046792,2047147..2048856); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase [fly-100309-contam.fasta]
  • CG3707-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • wings apart-like CG3707-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(2044910..2045185,2045305..2045495,2045556..2045644,2045710..2045879,2045950..2046792,2047147..2048856); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase:FBpp0070414,FlyBase_Annotation_IDs:CG3707-PB,REFSEQ:NP_726796,GB_protein:AAF45735; MD5=e2abaa4d71a6fc9d54081a36f1492f2d; length=1092; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(2044910..2045185,2045305..2045495,2045556..2045644,2045710..2045879,2045950..2046792,2047147..2048856); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase:FBpp0070414,FlyBase_Annotation_IDs:CG3707-PB,REFSEQ:NP_726796,GB_protein:AAF45735; MD5=e2abaa4d71a6fc9d54081a36f1492f2d; length=1092; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Isoform B of Protein wings apart-like OS=Drosophila melanogaster GN=wapl [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(2044910..2045185,2045305..2045495,2045556..2045644,2045710..2045879,2045950..2046792,2047147..2048856); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase:FBpp0070414,FlyBase_Annotation_IDs:CG3707-PB,REFSEQ:NP_726796,GB_protein:AAF45735,FlyMine:FBpp0070414,modMine:FBpp0070414; MD5=e2abaa4d71a6fc9d54081a36f1492f2d; length=1092; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(2153114..2154823,2151917..2152759,2151677..2151846,2151523..2151611,2151272..2151462,2150877..2151152)); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase:FBpp0070414,FlyBase_Annotation_IDs:CG3707-PB,REFSEQ:NP_726796,GB_protein:AAF45735,FlyMine:FBpp0070414,modMine:FBpp0070414; MD5=e2abaa4d71a6fc9d54081a36f1492f2d; length=1092; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(2153114..2154823,2151917..2152759,2151677..2151846,2151523..2151611,2151272..2151462,2150877..2151152)); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase:FBpp0070414,FlyBase_Annotation_IDs:CG3707-PB,REFSEQ:NP_726796,GB_protein:AAF45735,FlyMine:FBpp0070414,modMine:FBpp0070414; MD5=e2abaa4d71a6fc9d54081a36f1492f2d; length=1092; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9W517, Isoform B of Protein wings apart-like OS=Drosophila melanogaster GN=wapl [DROME.fasta.20160308]
  • FBpp0070414 type=protein; loc=X:complement(join(2153114..2154823,2151917..2152759,2151677..2151846,2151523..2151611,2151272..2151462,2150877..2151152)); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase:FBpp0070414,FlyBase_Annotation_IDs:CG3707-PB,REFSEQ:NP_726796,GB_protein:AAF45735,FlyMine:FBpp0070414,modMine:FBpp0070414; MD5=e2abaa4d71a6fc9d54081a36f1492f2d; length=1092; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(2153114..2154823,2151917..2152759,2151677..2151846,2151523..2151611,2151272..2151462,2150877..2151152)); ID=FBpp0070414; name=wapl-PB; parent=FBgn0004655,FBtr0070430; dbxref=GB_protein:AAF45735.1,GB_protein:AAF45735.2,FlyBase:FBpp0070414,FlyBase_Annotation_IDs:CG3707-PB,REFSEQ:NP_726796,GB_protein:AAF45735,FlyMine:FBpp0070414,modMine:FBpp0070414; MD5=e2abaa4d71a6fc9d54081a36f1492f2d; length=1092; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1092 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMMTIDGAGT GAASAVPETP LQEDILAVLR GEVPRLNGNT DPEPTEEEDQ QQQPKRATRG  60
   61 RGRKANNNVD VTPPATETRT RGRAKGADAT TAAISPPTGK RNTRGTRGSR KAEQEVDMEV 120
  121 DETAMTTVPA NEEQLEQATL PPRRGRNAAA RANNNNLASV NNNINKIAAN LSAKAEASRL 180
  181 AEGGVAGGAA RSYGRKRKNQ QVTQVLQQEP VPEEQETPDA EEEQPTPAKI PHTDHREHSP 240
  241 DHDPDPDPDE LSNNSNNSSL QHDGSSSSPP PRDFKFKDKF KRTLTLDTQG AANAGAGGAA 300
  301 AAAPPESSGE QRGAVKLVIS KKKGSIFKSR ALVPSDQAEQ ATVAKRHLYK HSWDAALEAN 360
  361 GGGTNSDASN ASASGVGVAG AKDHLHHLAA GKSDGDFGDS PSSNNNGSSS ACSSASTLRG 420
  421 DSPALGKISR LAGKQGVPAT STSSDAFDLD LEPIAGELDL ERSAAGASAG GTGATTGGGG 480
  481 ATGGGGPVRV DRKTKDYYPV VRNVKTAHQI QEIGEYQEMD DDVEYILDAL QPHNPPATRC 540
  541 LSALQLAAKC MMPAFRMHVR AHGVVTKFFK ALSDANKDLS LGLCTSAIMY ILSQEGLNMD 600
  601 LDRDSLELMI NLLEADGVGG STETGHPDRA GYDRNKQKVR ELCEEIKAQG KGTHLNVDSL 660
  661 TVGTLAMETL LSLTSKRAGE WFKEDLRKLG GLEHIIKTIS DFCRPVIACD TEIDWQPTLL 720
  721 DNMQTVARCL RVLENVTQHN ETNQRYMLTS GQGKAVETLC QLYRLCSRQI MLHPSDGGGS 780
  781 NKEHPGVAMR ELLVPVLKVL INLTHTFNEA QPSLGAELLG QRGDVVETSF RLLLLSANYI 840
  841 PDQCVFELSI LVLTLLINLC MHTVPNRAAL MQAAAPAEYV ADNPPAQGSV SALQALLEYF 900
  901 YKCEELARLV EKNTDAFLES NEKGKKKQEE VEETVNNLVQ RAGHHMEHTL KGSYAAILVG 960
  961 NLIADNELYE SVVRRQLRGN SFKEIIGVLE KYHTFMNLTS SLEAAFVAHM KSTKRIIDNF1020
 1021 KKRDYIYEHS DEHDNPLPLN LETTAQVLAV GADASHAATS STTVGSGSAP SSTSATGTTR1080
 1081 APRVYKTYSS HR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] MSA 2.27699 View MSA. No confident structure predictions are available.
    2 View Details [170..328] MSA 5.280988 View MSA. No confident structure predictions are available.
    3 View Details [329..533] deduced N/A No confident structure predictions are available.
    4 View Details [534..776] deduced N/A No confident structure predictions are available.
    5 View Details [777..926] deduced N/A No confident structure predictions are available.
    6 View Details [927..1092] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

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