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Protein Overview: CG1640-PB

General Information:
Name(s) found: CG1640-PB / FBpp0073600 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG1640 (CG1640, FBgn0030478). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13264639..13274193. It has the cytological map location 11F1. Based on sequence similarity, it is predicted to have molecular function</span>: L-alanine:2-oxoglutarate aminotransferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: biosynthetic process. 12 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 575 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: biosynthetic process [IEA]
    Molecular Function: pyridoxal phosphate binding [IEA]
    L-alanine:2-oxoglutarate aminotransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKNRKIMSR MLIKPAAATV SAALQQHQRQ QQQYVIRRWK SFLHNNSNNA NRRAAKSTAT  60
   61 ATVTAAATSQ RHGTSGDFIQ PLDVRRSFST SHKMPSSSKA LTLDNINPNF IAMEYAVRGP 120
  121 LVIRAGEIEK ELEKGVKKPF DQVIRANIGD CHAMGQQPLT FLRQLLALTF ETRLLDSPDY 180
  181 PEDVKKRACA ILNGCQGQSV GSYTDSAGLE VVRRQVAQYI EKRDGGIASN WQDIYLTGGA 240
  241 SPGIKSILSM INAEVGCKAP GVMVPIPQYP LYSATISEYG MTKVDYYLEE ETGWSLDRKE 300
  301 LQRSYDEAKK VCNPRALVVI NPGNPTGQVL TRENIEEIIK FAHDNKVLVL ADEVYQDNVY 360
  361 DKNSKFWSFK KVAYEMGDPY RNLEMVSFLS TSKGYLGECG IRGGYMEVLN LDPKVKAMLT 420
  421 KSITAALCST TAGQVAVSAL VNPPQPGEPS YDLYKKERDG ILAALKERAE LVHKALNSFE 480
  481 GYKVNPVQGA MYVFPQIEIP PKAIEAAKAK GMAPDVFYAF ELLETSGICI VPGSGFGQKP 540
  541 GTWHFRSTIL PQTDKLKLMM EKFRVFHAEF MKKYK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..137] PSI-BLAST 3.522879 Solution structure of Streptmycal repressor TraR
    2 View Details [138..575] PSI-BLAST 70.69897 Alanine aminotransferase from Pyrococcus furiosus Pfu-1397077-001

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.4536940012509 bayes_pls_golite062009
  • DNA binding
    		•  3.23093645092894 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.20789737823268 bayes_pls_golite062009
  • binding
    		•  2.97484655729009 bayes_pls_golite062009
  • transcription factor activity
    		•  2.61062802798523 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.28754561517213 bayes_pls_golite062009
  • transcription activator activity
    		•  1.13682518056041 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.99712200420162 bayes_pls_golite062009
  • protein binding
    		•  0.501337284874473 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.48900880427449 bayes_pls_golite062009
    2
    Term Confidence Notes
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  5.51961002550688 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • 4-aminobutyrate transaminase activity
    		•  1.82501790383768 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.63055151623667 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.63055151623667 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • L-alanine:2-oxoglutarate aminotransferase activity
    		•  1.06988190956423 bayes_pls_golite062009
  • alanine-oxo-acid transaminase activity
    		•  1.06988190956423 bayes_pls_golite062009
  • hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
    		•  0.942545094747784 bayes_pls_golite062009
  • hydrolase activity, acting on acid carbon-carbon bonds
    		•  0.845816961387768 bayes_pls_golite062009
  • N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
    		•  0.753443687983955 bayes_pls_golite062009
  • binding
    		•  0.536634592992536 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.319452731970428 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • aromatic-amino-acid:2-oxoglutarate aminotransferase activity
    		•  0.0916183433120769 bayes_pls_golite062009
  • kynureninase activity
    		•  0.0900983660305177 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.0833010353195099 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.013097682076602 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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