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Protein Overview: Rhp-PB, Rhp-PA

General Information:
Name(s) found: Rhp-PB / FBpp0089121 [FlyBase]
Rhp-PA / FBpp0073911 [FlyBase]
Description(s) found:
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  • gi|60678085|gb|AAX33549.1| LD12055p [Drosophila melanogaster] [NCBI NR]
  • gi|4868350|gb|AAD31273.1|AF132025_1 rhophilin [Drosophila melanogaster] [NCBI NR]
  • gi|45555274|ref|NP_996447.1| rhophilin, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45549133|ref|NP_511168.3| rhophilin, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|45446973|gb|AAS65348.1| rhophilin, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45446972|gb|AAF48516.3| rhophilin, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene Rhophilin is referred to in FlyBase by the symbol Dmel\Rhp (CG8497, FBgn0026374). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15682926..15687780. It has the cytological map location 13E18. Based on sequence similarity, it is predicted to have molecular function</span>: GTP-Rho binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: signal transduction. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • (AAF48516) CG8497-PA [DrosMelano7227.FASTAC.txt]
  • CG8497-PB, isoform B [Drosophila melanogaster]gi|45446972|gb|AAF48516.3| CG8497-PA, isoform A [Drosophila melanogaster]gi|45555274|ref|NP_996447.1| CG8497-PB [Drosophila melanogaster]gi|45549133|ref|NP_511168.3| CG8497-PA [Drosophila melanogaster]gi|4 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0089121; nam [fly-100309-contam.fasta]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0073911; nam [fly-100309-contam.fasta]
  • CG8497-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8497-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Rhophilin CG8497-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD12055p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Rhophilin CG8497-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • rhophilin [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0089121; name=Rhp-PB; parent=FBgn0026374,FBtr0074096; dbxref=GB_protein:AAS65348.1,FlyBase:FBpp0089121,FlyBase_Annotation_IDs:CG8497-PB,REFSEQ:NP_996447,GB_protein:AAS65348; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0073911; name=Rhp-PA; parent=FBgn0026374,FBtr0074095; dbxref=GB_protein:AAF48516.3,GB_protein:AAF48516.2,FlyBase:FBpp0073911,FlyBase_Annotation_IDs:CG8497-PA,REFSEQ:NP_511168,GB_protein:AAF48516; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0089121; name=Rhp-PB; parent=FBgn0026374,FBtr0074096; dbxref=GB_protein:AAS65348.1,FlyBase:FBpp0089121,FlyBase_Annotation_IDs:CG8497-PB,REFSEQ:NP_996447,GB_protein:AAS65348; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0073911; name=Rhp-PA; parent=FBgn0026374,FBtr0074095; dbxref=GB_protein:AAF48516.3,GB_protein:AAF48516.2,FlyBase:FBpp0073911,FlyBase_Annotation_IDs:CG8497-PA,REFSEQ:NP_511168,GB_protein:AAF48516; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • LD12055p OS=Drosophila melanogaster GN=Rhp PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0089121; name=Rhp-PB; parent=FBgn0026374,FBtr0074096; dbxref=GB_protein:AAS65348.1,FlyBase:FBpp0089121,FlyBase_Annotation_IDs:CG8497-PB,REFSEQ:NP_996447,GB_protein:AAS65348; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(15684323..15684421,15684776..15684892,15685012..15685139,15685276..15685429,15685495..15685935,15686021..15686177,15686243..15686490,15686551..15686680,15686745..15687070,15687125..15687277,15687342..15687545); ID=FBpp0073911; name=Rhp-PA; parent=FBgn0026374,FBtr0074095; dbxref=GB_protein:AAF48516.3,GB_protein:AAF48516.2,FlyBase:FBpp0073911,FlyBase_Annotation_IDs:CG8497-PA,REFSEQ:NP_511168,GB_protein:AAF48516,FlyMine:FBpp0073911,modMine:FBpp0073911; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0089121; name=Rhp-PB; parent=FBgn0026374,FBtr0074096; dbxref=GB_protein:AAS65348.1,FlyBase:FBpp0089121,FlyBase_Annotation_IDs:CG8497-PB,REFSEQ:NP_996447,GB_protein:AAS65348; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0073911; name=Rhp-PA; parent=FBgn0026374,FBtr0074095; dbxref=GB_protein:AAF48516.3,GB_protein:AAF48516.2,FlyBase:FBpp0073911,FlyBase_Annotation_IDs:CG8497-PA,REFSEQ:NP_511168,GB_protein:AAF48516,FlyMine:FBpp0073911,modMine:FBpp0073911; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0089121; name=Rhp-PB; parent=FBgn0026374,FBtr0074096; dbxref=GB_protein:AAS65348.1,FlyBase:FBpp0089121,FlyBase_Annotation_IDs:CG8497-PB,REFSEQ:NP_996447,GB_protein:AAS65348; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0073911; name=Rhp-PA; parent=FBgn0026374,FBtr0074095; dbxref=GB_protein:AAF48516.3,GB_protein:AAF48516.2,FlyBase:FBpp0073911,FlyBase_Annotation_IDs:CG8497-PA,REFSEQ:NP_511168,GB_protein:AAF48516,FlyMine:FBpp0073911,modMine:FBpp0073911; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0089121 type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0089121; name=Rhp-PB; parent=FBgn0026374,FBtr0074096; dbxref=GB_protein:AAS65348.1,FlyBase:FBpp0089121,FlyBase_Annotation_IDs:CG8497-PB,REFSEQ:NP_996447,GB_protein:AAS65348; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0073911 type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0073911; name=Rhp-PA; parent=FBgn0026374,FBtr0074095; dbxref=GB_protein:AAF48516.3,GB_protein:AAF48516.2,FlyBase:FBpp0073911,FlyBase_Annotation_IDs:CG8497-PA,REFSEQ:NP_511168,GB_protein:AAF48516,FlyMine:FBpp0073911,modMine:FBpp0073911; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0089121; name=Rhp-PB; parent=FBgn0026374,FBtr0074096; dbxref=GB_protein:AAS65348.1,FlyBase:FBpp0089121,FlyBase_Annotation_IDs:CG8497-PB,REFSEQ:NP_996447,GB_protein:AAS65348,UniProt/TrEMBL:Q9XYY9; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=X:join(15790290..15790388,15790743..15790859,15790979..15791106,15791243..15791396,15791462..15791902,15791988..15792144,15792210..15792457,15792518..15792647,15792712..15793037,15793092..15793244,15793309..15793512); ID=FBpp0073911; name=Rhp-PA; parent=FBgn0026374,FBtr0074095; dbxref=GB_protein:AAF48516.3,GB_protein:AAF48516.2,FlyBase:FBpp0073911,FlyBase_Annotation_IDs:CG8497-PA,REFSEQ:NP_511168,GB_protein:AAF48516,UniProt/TrEMBL:Q9XYY9,FlyMine:FBpp0073911,modMine:FBpp0073911; MD5=b925dfd087efa187005bfd102c29fa16; length=718; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 718 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: signal transduction [IEA]
    Molecular Function: GTP-Rho binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEKEHELST RVVKNEENED DEKLNELSFC FVRGSDPRAA TCRSKLQNRR CKLNKEINKE  60
   61 LRLRAGAENL YKATSNRKLR DTVALELSFV NSNLQLLKEQ LAELNSSVEI YQSESHNGIM 120
  121 PMIPLGLKET KEINFMEPFS DFILEHYSEE PSMYIDAIAD MTDTRQASKT PSRDALGVAL 180
  181 LFRYYNTLYY VERRFFPPDR NLGVYFEWYD SLTGVPSCQR TIAFEKACTL FNLGGIYTQI 240
  241 GARHDRTTER GLDLAVDSFL RAAGVFRHIY DTFTNAPSMD LKPQVLDVLV SLMLSQAREC 300
  301 LFEKLQLQIE AMSHDCQAFR DLAGEAAQIS HEYNEMHKNI QANDTHTYLP ECWAGLVPVK 360
  361 AELYKAFAHF YKARSIDATD ELKASKSSQK NQESFIGNSQ EVERITTADY GASDEASTSI 420
  421 ANKLAHLKEA LASIEEAQRL QRMCRFLKNK ASLTEVMKEV HSKSQEELEK FRLQASAKNI 480
  481 EDGDLLERSV EASSKFTLSL TGPDFTSHKV KDPFKRLGPI AIFSARRHWT APRCVRLQKG 540
  541 SSLYHSVPSN DNKCPLDNDD DEEHDGGYNL YKEEFENFGF HVRGDAPVII AHVEINSLAD 600
  601 LGGIKEGDFI VEIAGVDVKW YSHQQVVQLI QSCGSTLELR VITPMDRNYL KPLSSKGSLS 660
  661 TLSAASSSGI SSGFPSPTSI AAKPKLHLKT SSSSRPAGSV SSSSWNPFRR TPSLAKIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] PSI-BLAST 18.39794 Effector domain of the protein kinase pkn/prk1
    2 View Details [113..429] PSI-BLAST 73.69897 No description for 2oevA was found.
    3 View Details [430..527] FFAS03 1.54 Structure basis for endosomal targeting by the Bro1 domain
    4 View Details [528..718] PSI-BLAST 22.0 solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle