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Protein Overview: gi|62642886, gi|...

General Information:
Name(s) found: gi|62642886 [NCBI NR]
gi|56797761 [NCBI NR]
gi|34854161 [NCBI NR]
gi|32264599 [NCBI NR]
Description(s) found:
Found 12 descriptions.
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  • gi|62642886|ref|XP_579200.1| PREDICTED: interleukin 6 signal transducer [Rattus norvegicus] [NCBI NR]
  • gi|56797761|ref|NP_001008725.1| interleukin 6 signal transducer [Rattus norvegicus] [NCBI NR]
  • ref|XP_215483.2| interleukin 6 signal transducer [Rattus norvegicus] [NCBI NR]
  • gi|32264599|gb|AAP78746.1| Ac1055 [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 1010 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN]
    oncostatin-M receptor complex [UNKNOWN][IEA]
    membrane [IEA]
    ciliary neurotrophic factor receptor complex [UNKNOWN][IEA]
    external side of plasma membrane [UNKNOWN][IEA]
    integral to membrane [IEA]
    cellular_component [ND]
    interleukin-6 receptor complex [UNKNOWN][IEA]
    Biological Process: response to cytokine stimulus [UNKNOWN][IEA]
    positive regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN][IEA]
    signal transduction [UNKNOWN][IEA]
    regulation of Notch signaling pathway [UNKNOWN][IEA]
    positive regulation of cell proliferation [UNKNOWN][IEA]
    reduction of cytosolic calcium ion concentration [IMP]
    response to nutrient [IEP]
    positive regulation of astrocyte differentiation [UNKNOWN]
    positive regulation of T cell proliferation [UNKNOWN][IEA]
    positive regulation of osteoblast differentiation [UNKNOWN][IEA]
    positive regulation of tyrosine phosphorylation of Stat1 protein [UNKNOWN][IEA]
    triglyceride mobilization [IMP]
    JAK-STAT cascade [IMP]
    positive regulation of cell growth [TAS]
    glycogen metabolic process [UNKNOWN][IEA]
    regulation of hormone secretion [TAS]
    cytokine-mediated signaling pathway [UNKNOWN]
    leukemia inhibitory factor signaling pathway [UNKNOWN][IEA]
    ciliary neurotrophic factor-mediated signaling pathway [UNKNOWN][IEA]
    negative regulation of interleukin-6-mediated signaling pathway [UNKNOWN]
    positive regulation of smooth muscle cell migration [IMP]
    interleukin-27-mediated signaling pathway [UNKNOWN][IEA]
    Molecular Function: growth factor binding [UNKNOWN]
    receptor activity [IEA]
    cytokine activity [TAS]
    cytokine receptor activity [IEA]
    ciliary neurotrophic factor receptor binding [UNKNOWN][IEA]
    interleukin-6 receptor binding [UNKNOWN][IEA]
    ciliary neurotrophic factor receptor activity [UNKNOWN]
    interleukin-11 receptor activity [UNKNOWN][IEA]
    protein binding [UNKNOWN]
    oncostatin-M receptor activity [UNKNOWN][IEA]
    leukemia inhibitory factor receptor activity [UNKNOWN][IEA]
    interleukin-6 receptor activity [UNKNOWN][IEA]
    interleukin-11 binding [UNKNOWN]
    interleukin-6 binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKQIFLEIQ HGQLVEPCGY IYPEFPVVQR GSNFTATCVL KEKCLQVYSV NATYIVWKTN  60
   61 HVAVPKEQVT VINRTASSVT FTDVVFQNVQ LTCNILSFGQ IEQNVYGITI LSGYPPDIPT 120
  121 NLSCIVNEGK NMLCQWDPGR ETYLETNYTL KSEWATEKFP DCRTKHGTSS CMMGYTPIYF 180
  181 VNIEVWVEAE NALGNVSSEP INFDPVDKVK PSPPHNLSVT NSEELSSILK LAWVNSGLDS 240
  241 ILRLKSDIQY RTKDASTWIQ VPLEDTVSPR TSFTVQDLKP FTEYVFRIRS IKENGKGYWS 300
  301 DWSEEASGTT YEDRPSKAPS FWYKVNANHP QEYRSARLIW KTLPLSEANG KILDYEVVLT 360
  361 QSKSVSQTYT VNGTELIVNL TNNRYVASLA ARNVVGKSPA TVLTIPGSHF KVDLKAFPKD 420
  421 NLLWVEWTPP SKPVNKYILE WCVLSENSPC IPDWQQEDGT VNRTHLRGSL LESKCYLITV 480
  481 TPVFPGGPGS PESMKAYLKQ AAPSKGPTVR TKKVGKNEAV LEWDHLPVDV QNGFIRNYSI 540
  541 SYRTSVGKEM VVRVDSSHTE YTLSSLSSDT LYMVHMAAYT EEGGKDGPEF TFTTLKFGES 600
  601 SCAASGLMSI AVNSWPTADA SSFDDCYQIK KHIWPNVPDP SKSHIAQWSP HTPPRHNFNS 660
  661 KDQMYSDANF TDVSVVEIEA NNKKPCPDDL KSLDLFKKEK ISTEGHSSGI GGSSCMSSSR 720
  721 PSISSSEENE SAQSTASTVQ YSTVVHSGYR HQVPSVQVFS RSESTQPLLD SEERPEDLQL 780
  781 VDSVDSGDEI LPRQQYFKQS CSQPGASPDV SHFERSSQVP SGSEEDFVRL KQQQVSDHIS 840
  841 EPYGSEQRRL FQEGSVADAL GTGTDGQIER FESVGMETAM DEDISKSYLP QTVRQGGYMP 900
  901 HANIKVVRHQ AQSTLVLIVD RPPEVQDSSQ RTQLEHKLRQ LHAHSLSNKL ELNSFNQSPD 960
  961 GQASSQSEPT AFSSVNRRDT PVDIWHSQVK TKMATENWTN SSSFFHPCKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle