Protein Overview: gi|34421001, gi|...

General Information:
Name(s) found:	gi\|39930495 [NCBI NR] gi\|34421001 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|39930495\|ref\|NP_446018.1\| patched homolog 1 [Rattus norvegicus] [NCBI NR] gi\|34421001\|gb\|AAQ67738.1\| patched [Rattus norvegicus] [NCBI NR] patched (Drosophila) homolog [HMR_022704-rand.fasta] patched [Rattus norvegicus]gi\|39930495\|ref\|NP_446018.1\| patched (Drosophila) homolog [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Patched [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] patched homolog 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] patched [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PATCHED [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ptch1 Patched [rat-ipi-250309-contam.fasta] Patched OS=Rattus norvegicus GN=Ptch1 [011711_HMR.fasta] Patched OS=Rattus norvegicus GN=Ptch1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1434 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] cellular_component [ND]
Biological Process:	negative regulation of multicellular organism growth [UNKNOWN][ISS] epidermis development [UNKNOWN][IEA] mammary gland duct morphogenesis [UNKNOWN][IEA] mammary gland epithelial cell differentiation [UNKNOWN][IEA] regulation of smoothened signaling pathway [UNKNOWN][ISS] response to mechanical stimulus [IEP] dorsal/ventral pattern formation [UNKNOWN][ISS] embryonic limb morphogenesis [UNKNOWN][ISS] heart morphogenesis [UNKNOWN][IEA] response to retinoic acid [IEP] neural tube closure [UNKNOWN][IEA] hindlimb morphogenesis [UNKNOWN][IEA] response to chlorate [UNKNOWN][IEA] dorsal/ventral neural tube patterning [UNKNOWN][IEA] keratinocyte proliferation [UNKNOWN][IEA] smoothened signaling pathway [UNKNOWN][ISS] pattern specification process [UNKNOWN][IEA] response to organic cyclic substance [IEP] regulation of growth [UNKNOWN][IEA] organ morphogenesis [UNKNOWN][ISS] mammary gland development [UNKNOWN] response to drug [IEP] glucose homeostasis [UNKNOWN][IEA] negative regulation of epithelial cell proliferation [UNKNOWN][IEA] response to estradiol stimulus [IEP] protein processing [UNKNOWN][ISS]
Molecular Function:	protein binding [UNKNOWN] hedgehog receptor activity [IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASAGNAAGA LGRQAGGGRR RRTGGPHRAA PDRDYLHRPS YCDAAFALEQ ISKGKATGRK  60
   61 APLWLRAKFQ RLLFKLGCYI QKNCGKFLVV GLLIFGAFAV GLKAANLETN VEELWVEVGG 120
  121 RVSRELNYTR QKIGEEAMFN PQLMIQTPKE EGANVLTTEA LLQHLDSALQ ASRVHVYMYN 180
  181 RQWKLEHLCY KSGELITETG YMDQIIEYLY PCLIITPLDC FWEGAKLQSG TAYLLGKPPL 240
  241 RWTNFDPLEF LEELKKINYQ VDSWEEMLNK AEVGHGYMDR PCLNPADPDC PATAPNKNST 300
  301 KPLDVALVLN GGCQGLSRKY MHWQEELIVG GTVKNATGKL VSAHALQTMF QLMTPKQMYE 360
  361 HFRGYDYVSH INWNEDRAAA ILEAWQRTYV EVVHQSVAPN STQKVLSFTT TTLDDILKSF 420
  421 SDVSVIRVAS GYLLMLAYAC LTMLRWDCSK SQGAVGLAGV LLVALSVAAG LGLCSLIGIS 480
  481 FNAATTQVLP FLALGVGVDD VFLLAHAFSE TGQNKRIPFE DRTGECLKRT GASVALTSIS 540
  541 NVTAFFMAAL IPIPALRAFS LQAAVVVVFN FAMVLLIFPA ILSMDLYRRE DRRLDIFCCF 600
  601 TSPCVSRVIQ VEPQAYTEPH SNTRYSPPPP YSSHSFAHET HITMQSTVQL RTEYDPHTHV 660
  661 YYTTAEPRSE ISVQPVTITQ DTLSCQSPES TSSTRDLLSQ FSDSSLHCLE PPCTKWTLSS 720
  721 FAEKHYAPFL LRPKAKVVVI LLFLGLLGVS LYGTTRVRDG LDLTDIVPRE TREYDFIAAQ 780
  781 FKYFSFYNMY IVTQKADYPN IQHLLYDLHK SFSSVKYVML EENKQLPQMW LHYFRDWLQG 840
  841 LQDAFDSDWE TGRIMPNNYK NGSDDGVLAY KLLVQTGSRD KPIDISQLTK QRLVDADGII 900
  901 NPSAFYIYLT AWVSNDPVAY AASQANIRPH RPEWVHDKAD YMPETRLRIP AAEPIEYAQF 960
  961 PFYLNGLRDT SDFVEAIEKV RVICNNYTSL GLSSYPNGYP FLFWEQYISL RHWLLLAISV1020
 1021 VLACTFLVCA VFLLNPWTAG IIVMVLALMT VELFGMMGLI GIKLSAVPVV ILIASVGIGV1080
 1081 EFTVHVALAF LTAIGDKNHR AMLALEHMFA PVLDGAVSTL LGVLMLAGSE FDFIVRYFFA1140
 1141 VLAILTVLGV LNGLVLLPVL LSFFGPCPEV SPANGLNRLP TPSPEPPPSV VRFAVPPGHT1200
 1201 NNGSDSSDSE YSSQTTVSGI SEELRHYEAQ QGTGGPAHQV IVEATENPVF ARSTVVHPDS1260
 1261 RHQPPLNSRQ QPHLDSGSLS PGRQGQQPRR DPPREGLRPP PYRPRRDAFE ISTEGHSGPS1320
 1321 NRDRSGPHGA RSHNPRNPTS TAMGSSVPSY CQPITTVTAS ASVTVAVHPP PGPGRNPRGG1380
 1381 PCPGYESYPE TDHGVFEDPH VPFHVRCERR DSKVEVIELQ DVECEERPWG SSSN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: gi|34421001, gi|...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: