Protein Overview: OPI3

General Information:
Name(s) found:	OPI3 / YJR073C [SGD]
Description(s) found: Found 34 descriptions. SHOW ALL	Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis [SGD]
Organism:	Saccharomyces cerevisiae
Length:	206 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA ] endoplasmic reticulum [TAS]
Biological Process:	phosphatidylcholine biosynthetic process [TAS]
Molecular Function:	phosphatidyl-N-methylethanolamine N-methyltransferase activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKESVQEIIQ QLIHSVDLQS SKFQLAIVCT MFNPIFWNIV ARMEYHKHSL TKMCGGARKG  60
   61 CYMLAATIFS LGIVRDMVYE SALREQPTCS LITGENWTKL GVALFGLGQV LVLSSMYKLG 120
  121 ITGTYLGDYF GILMDERVTG FPFNVSNNPM YQGSTLSFLG IALYKGKPAG LVVSAVVYFM 180
  181 YKIALRWEEP FTAMIYANRD KAKKNM

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		CHO2 OPI3

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#22 Asynchronous Prep2-IMAC Phosphopeptide enrichment B1-2	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RTT101	OPI3	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	OPI3	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..132]	MSA	1.005974	View MSA. Confident ab initio structure predictions are available.
2	View Details	[133..206]	MSA	1.005984	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2