Protein Overview: YDC1

General Information:
Name(s) found:	YDC1 / YPL087W [SGD]
Description(s) found: Found 30 descriptions. SHOW ALL	Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity [SGD]
Organism:	Saccharomyces cerevisiae
Length:	317 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	response to heat [IMP] ceramide metabolic process [IMP]
Molecular Function:	ceramidase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFSWPYPEA PIEGYWGKPT SLIDWCEENY VVSPYIAEWS NTITNSIFLM TAFYSTYSAW  60
   61 RNKLETRYIL IGMGFSLVGI GSWLFHMTLQ YRYQLLDELP MLYATIIPSW SIFAETQEIL 120
  121 IKDEKKRKES SFRIQMVISF IMCGIVTILT WIYVVVQKPA IFQVLYGILT LLVVVLSGWL 180
  181 TYYHVHDSFA KKNLFITMVM GMIPFVIGFI CWQLDIHLCS FWIYIRRTYL ALPLGVLLEL 240
  241 HAWWHLLTGT GVYIFVVYLQ YLRILTHGNP NDFLFIWRWG FFPELVRKGL PIGTSYSLEY 300
  301 LGPIVNTQVD DETKKNN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		YDC1 YPC1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	BUR2	YDC1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YDC1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..317]	MSA	4.020953	View MSA. No confident structure predictions are available.
2	View Details	[86..317]	FFAS03	1.93	Rhodopsin

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2