The National Center for Research Resources' Yeast Resource Center is located at the University of Washington in Seattle, Washington. The mission of the center is to facilitate the identification and characterization of protein complexes in the yeast Saccharomyces cerevisiae. We provide expertise and access to four advanced technologies: mass spectrometry, two-hybrid arrays, deconvolution fluorescence microscopy and protein structure prediction. Through collaborations with YRC personnel these critical, but costly, technologies are made available to a large community of researchers throughout the country. The investigators participating in the YRC include Dr. John Yates and Dr. Ruedi Aebersold for mass spectrometry, Dr. Stan Fields for two-hybrid analysis, Dr. Trisha Davis and Dr. Eric Muller for fluorescence microscopy, and Dr. David Baker for protein structure prediction.

These services are provided to further the goal of a complete understanding of the chemical interactions required for the maintenance and faithful reproduction of a living cell. The observation that the fundamental biological processes of yeast are conserved among all eukaryotes ensures that this knowledge will shape and advance our understanding of living systems.

To learn more about the YRC, please click here to visit our site (opens new browser window).