YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|6730422
Organism:	Escherichia coli
Length:	199 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|6730422.

Description	E-value	Query Range	Subject Range
gi\|106770932, gi... - gi\|148654599\|ref\|YP_001274804.1\| pyridoxamine 5'-phosphate oxidase [Roseiflexus sp. RS-1], gi\|148566...	280.0	[0..2]	[199..14]
PDXH_SHIFL - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Shigella flexneri GN=pdxH PE=3 SV=2 gi\|83569261, gi\|... - gi\|83569261\|ref\|ZP_00920718.1\| COG0259: Pyridoxamine-phosphate oxidase [Shigella dysenteriae 1012], ... PDXH_ECOLI - Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5) (PNP/PMP oxidase) (PNPOx) - Escherichia coli gi\|24113028, gi\|... - gi\|24113028\|ref\|NP_707538.1\| pyridoxamine 5'-phosphate oxidase [Shigella flexneri 2a str. 301], gi\|2... gi\|30063153, gi\|... - gi\|30063153\|ref\|NP_837324.1\| pyridoxamine 5'-phosphate oxidase [Shigella flexneri 2a str. 2457T], gi... gi\|188491170, gi... - gi\|75512929\|ref\|ZP_00735410.1\| COG0259: Pyridoxamine-phosphate oxidase [Escherichia coli 53638], gi\|... EG11487 - pyridoxine 5'-phosphate oxidase / Pyridoxine /pyridoxamine phosphate (PNP /PMP) oxidase; isoniazid res... gi\|89108480, gi\|... - gi\|89108480\|ref\|AP_002260.1\| pyridoxine 5'-phosphate oxidase [Escherichia coli str. K-12 substr. W31... gi\|194436464, gi... - gi\|83587973\|ref\|ZP_00926599.1\| COG0259: Pyridoxamine-phosphate oxidase [Escherichia coli 101-1], gi\|... PDXH_SHIF8 - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Shigella flexneri serotype 5b (strain 8401) GN=pdxH ... PDXH_ECOHS - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli O9:H4 (strain HS) GN=pdxH PE=3 SV=1 PDXH_ECOLU - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)... EG11487 - pyridoxine 5'-phosphate oxidase / Pyridoxine /pyridoxamine phosphate (PNP /PMP) oxidase; isoniazid res... PDXH_ECOLC - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Croo... PDXH_SHIBS - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Shigella boydii serotype 4 (strain Sb227) GN=pdxH PE... sp\|B7URX9\|PDXH_ECO27 - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN... PDXH_SHIDS - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=pd... PDXH_ECODH - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli (strain K12 / DH10B) GN=pdxH PE=3 S... PDXH_ECO27 - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN... gi\|124529205, gi... - gi\|124529205\|ref\|ZP_01700280.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli B], gi\|124499979... PDXH_ECOBW - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=p... gi\|251785096, gi... - gi\|251785096\|ref\|YP_002999400.1\| hypothetical protein B21_01598 [Escherichia coli BL21], gi\|24237736... gi\|254288489, gi... - gi\|254288489\|ref\|YP_003054237.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli BL21(DE3)], gi\|... gi\|254161700, gi... - gi\|254161700\|ref\|YP_003044808.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli B str. REL606],...	277.0	[0..1]	[199..20]
PDXH_ECO5E - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=p... gi\|208821813, gi... - gi\|208821813\|ref\|ZP_03262133.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4... gi\|217328903, gi... - gi\|217328903\|ref\|ZP_03444984.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. TW1... gi\|195939028 - gi\|195939028\|ref\|ZP_03084410.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4... gi\|189370944, gi... - gi\|189370944\|gb\|EDU89360.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC869],... gi\|254793255, gi... - gi\|254793255\|ref\|YP_003078092.1\| pyridoxine 5'-phosphate oxidase [Escherichia coli O157:H7 str. TW14... PDXH_ECO57 - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Escherichia coli O157:H7 GN=pdxH PE=3 SV=1 gi\|208731057, gi... - gi\|208816714\|ref\|ZP_03257834.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4... gi\|25284781, gi\|... - pir\|\|G85770 pyridoxinephosphate oxidase [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|208810284, gi... - gi\|208810284\|ref\|ZP_03252160.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4... gi\|189360014, gi... - gi\|189360014\|gb\|EDU78433.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4486]... gi\|12515630, gi\|... - gi\|15802052\|ref\|NP_288074.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 EDL933], gi... gi\|189364999, gi... - gi\|189364999\|gb\|EDU83415.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4501]... gi\|188999208, gi... - gi\|188999208\|gb\|EDU68194.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4076]... gi\|187768649, gi... - gi\|187768649\|gb\|EDU32493.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4196]... gi\|189354268, gi... - gi\|189354268\|gb\|EDU72687.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4401]... gi\|188013553, gi... - gi\|188013553\|gb\|EDU51675.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4113]... gi\|15831601, gi\|... - gi\|15831601\|ref\|NP_310374.1\| pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. Sakai]...	276.0	[0..1]	[199..20]
gi\|153220603, gi... - gi\|153220603\|ref\|ZP_01951737.1\| pyridoxamine 5`-phosphate oxidase [Vibrio cholerae MAK 757], gi\|1241... gi\|229605323, gi... - gi\|229605323\|ref\|YP_002876027.1\| pyridoxamine 5'-phosphate oxidase [Vibrio cholerae MJ-1236], gi\|229... gi\|124123170, gi... - gi\|153801255\|ref\|ZP_01955841.1\| pyridoxamine 5`-phosphate oxidase [Vibrio cholerae MZO-3], gi\|124123... gi\|153816753, gi... - gi\|153816753\|ref\|ZP_01969420.1\| pyridoxamine 5`-phosphate oxidase [Vibrio cholerae NCTC 8457], gi\|12... gi\|229510355, gi... - gi\|229510355\|ref\|ZP_04399835.1\| pyridoxamine 5'-phosphate oxidase [Vibrio cholerae B33], gi\|22935280... gi\|75831854, gi\|... - gi\|75831854\|ref\|ZP_00761114.1\| COG0259: Pyridoxamine-phosphate oxidase [Vibrio cholerae MO10], gi\|25... gi\|75821867, gi\|... - gi\|75821867\|ref\|ZP_00751621.1\| COG0259: Pyridoxamine-phosphate oxidase [Vibrio cholerae RC385], gi\|1... gi\|121628962, gi... - gi\|75814981\|ref\|ZP_00745516.1\| COG0259: Pyridoxamine-phosphate oxidase [Vibrio cholerae V52], gi\|121... gi\|153827782, gi... - gi\|153827782\|ref\|ZP_01980449.1\| pyridoxamine 5`-phosphate oxidase [Vibrio cholerae 623-39], gi\|14887... PDXH_VIBCM - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Vibrio cholerae serotype O1 (strain M66-2) GN=pdxH P... gi\|229505790, gi... - gi\|229505790\|ref\|ZP_04395299.1\| pyridoxamine 5'-phosphate oxidase [Vibrio cholerae BX 330286], gi\|22... gi\|229514484, gi... - gi\|229514484\|ref\|ZP_04403945.1\| pyridoxamine 5'-phosphate oxidase [Vibrio cholerae TMA 21], gi\|22934... gi\|229345549, gi... - gi\|229517513\|ref\|ZP_04406958.1\| pyridoxamine 5'-phosphate oxidase [Vibrio cholerae RC9], gi\|22934554... PDXH_VIBCH - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El ... gi\|121585969, gi... - gi\|121585969\|ref\|ZP_01675762.1\| pyridoxamine 5`-phosphate oxidase [Vibrio cholerae 2740-80], gi\|1215... gi\|229526380, gi... - gi\|229526380\|ref\|ZP_04415784.1\| pyridoxamine 5'-phosphate oxidase [Vibrio cholerae bv. albensis VL42... PDXH_VIBCH - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Vibrio cholerae GN=pdxH PE=3 SV=1 gi\|153216493, gi... - gi\|153216493\|ref\|ZP_01950494.1\| pyridoxamine 5`-phosphate oxidase [Vibrio cholerae 1587], gi\|1241142... gi\|229528037, gi... - gi\|229528037\|ref\|ZP_04417428.1\| pyridoxamine 5'-phosphate oxidase [Vibrio cholerae 12129(1)], gi\|229...	276.0	[0..1]	[199..13]
PDXH_MARHV - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Marinobacter hydrocarbonoclasticus (strain ATCC 7004...	276.0	[0..2]	[199..14]
gi\|37677308, gi\|... - gi\|37677308\|ref\|NP_937704.1\| pyridoxamine 5'-phosphate oxidase [Vibrio vulnificus YJ016], gi\|3720185...	275.0	[0..1]	[199..49]
gi\|77975317 - gi\|77975317\|ref\|ZP_00830853.1\| COG0259: Pyridoxamine-phosphate oxidase [Yersinia frederiksenii ATCC ...	275.0	[0..1]	[199..42]
PDXH_VIBC3 - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Cla...	275.0	[0..1]	[199..13]
PDXH_VIBVU - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Vibrio vulnificus (strain CMCP6) GN=pdxH PE=3 SV=1 PDXH_VIBVU - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Vibrio vulnificus GN=pdxH PE=3 SV=1 PDXH_VIBVY - Pyridoxine/pyridoxamine 5'-phosphate oxidase OS=Vibrio vulnificus (strain YJ016) GN=pdxH PE=3 SV=2	274.0	[0..1]	[199..13]
PDXH2_THICR - Pyridoxine/pyridoxamine 5'-phosphate oxidase 2 OS=Thiomicrospira crunogena (strain XCL-2) GN=pdxH2 P...	273.0	[0..2]	[199..16]

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Predicted Domain #1

Region A:
Residues: [1-199]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGLRRRDLPA DPLTLFERWL SQACEAKLAD PTAXVVATVD EHGQPYQRIV LLKHYDEKGX  60
   61 VFYTNLGSRK AHQIENNPRV SLLFPWHTLE RQVXVIGKAE RLSTLEVXKY FHSRPRDSQI 120
  121 GAWVSKQSSR ISARGILESK FLELKQKFQQ GEVPLPSFWG GFRVSLEQIE FWQGGEHRLH 180
  181 DRFLYQREND AWKIDRLAP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.69897
Match:	1g76A
Description:	Pyridoxine 5'-phoshate oxidase (PNP oxidase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pyridoxamine-phosphate oxidase activity	3.81533880638523	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1.18444956617957	bayes_pls_golite062009
catalytic activity	0.660906721832294	bayes_pls_golite062009
oxidoreductase activity	0.0268904833845668	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: