YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16975219
Organism:	Escherichia coli
Length:	152 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16975219.

Description	E-value	Query Range	Subject Range
gi\|148654385, gi... - gi\|148654385\|ref\|YP_001274590.1\| integral membrane sensor hybrid histidine kinase [Roseiflexus sp. R...	174.0	[0..1]	[150..268]
gi\|71839290, gi\|... - gi\|71839290\|ref\|ZP_00679041.1\| PAS [Pelobacter propionicus DSM 2379], gi\|71740223\|gb\|EAO35390.1\| PAS...	172.0	[0..2]	[148..706]
gi\|86609102 - gi\|86609102\|ref\|YP_477864.1\| sensory box histidine kinase/response regulator [Cyanobacteria bacteriu... gi\|86557644, gi\|... - gi\|86609102\|ref\|YP_477864.1\| sensory box histidine kinase/response regulator [Synechococcus sp. JA-2...	171.0	[0..3]	[150..888]
gi\|45358866, gi\|... - gi\|45358866\|ref\|NP_988423.1\| sensory transduction histidine kinase [Methanococcus maripaludis S2], g...	169.0	[0..1]	[149..486]
gi\|86554855, gi\|... - gi\|86606313\|ref\|YP_475076.1\| sensory box histidine kinase/response regulator [Synechococcus sp. JA-3... gi\|86606313 - gi\|86606313\|ref\|YP_475076.1\| sensory box histidine kinase/response regulator [Cyanobacteria bacteriu...	169.0	[0..3]	[150..896]
gi\|146274262, gi... - gi\|98660942\|dbj\|GAA01932.1\| unnamed protein product [Pelotomaculum thermopropionicum SI], gi\|1476781...	169.0	[0..1]	[152..307]
gi\|88603925, gi\|... - gi\|88603925\|ref\|YP_504103.1\| multi-sensor signal transduction histidine kinase [Methanospirillum hun...	169.0	[0..1]	[147..492]
gi\|20809032 - gi\|20809032\|ref\|NP_624203.1\| Sensory transduction histidine kinase [Thermoanaerobacter tengcongensis... gi\|20809032, gi\|... - gi\|20809032\|ref\|NP_624203.1\| sensory transduction histidine kinase [Thermoanaerobacter tengcongensis...	168.0	[0..2]	[143..424]
gi\|76873989, gi\|... - gi\|77359078\|ref\|YP_338653.1\| sensor protein [Pseudoalteromonas haloplanktis TAC125], gi\|76873989\|emb...	168.0	[0..1]	[152..597]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RELHPVAPLL DNLTSALNKV YQRKGVNISL DISPEISFVG EQNDFVEVMG NVLDNACKYC  60
   61 LEFVEISARQ TDEHLYIVVE DDGPGIPLSK REVIFDRGQR VDTLRPGQGV GLAVAREITE 120
  121 QYEGKIVAGE SMLGGARMEV IFGRQHSAPK DE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.69897
Match:	1id0A
Description:	Histidine kinase PhoQ domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.57884608485164	bayes_pls_golite062009
transferase activity	0.66560190725226	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.65281383212182	bayes_pls_golite062009
kinase activity	0.64987928624127	bayes_pls_golite062009
signal transducer activity	0.47895126364598	bayes_pls_golite062009
molecular transducer activity	0.47895126364598	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.41458536707017	bayes_pls_golite062009
protein kinase activity	0.41262128363539	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	0.270144402236579	bayes_pls_golite062009
protein histidine kinase activity	0.27006997723077	bayes_pls_golite062009
two-component sensor activity	0.22080838371957	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: