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View Structure Prediction Details

Protein: TFB1A_ARATH
Organism: Arabidopsis thaliana
Length: 591 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFB1A_ARATH.

Description E-value Query
Range
Subject
Range
gi|6850833, gi|1... - gi|6850833|emb|CAB71072.1| putative protein [Arabidopsis thaliana], gi|15233107|ref|NP_191701.1| tra...
575.0 [0..31] [582..1]
gi|34856117, gi|... - gi|34856117|ref|XP_341864.1| PREDICTED: similar to TFIIH basal transcription factor complex p62 subu...
572.0 [0..6] [583..11]
gi|114636459, gi... - gi|114636461|ref|XP_001173127.1| PREDICTED: general transcription factor IIH, polypeptide 1, 62kDa i...
572.0 [0..6] [583..11]
gi|30584247, gi|... - gi|60653005|gb|AAX29197.1| general transcription factor IIH polypeptide 1 62kDa [synthetic construct...
571.0 [0..6] [583..11]
GTF2H1 - general transcription factor IIH, polypeptide 1, 62kDa
gi|168277836, gi... - gi|168277836|dbj|BAG10896.1| TFIIH basal transcription factor complex p62 subunit [synthetic constru...
571.0 [0..6] [583..11]
gi|57102734 - gi|57102734|ref|XP_534083.1| PREDICTED: similar to TFIIH basal transcription factor complex p62 subu...
569.0 [0..6] [583..11]
gi|12836734, gi|... - gi|31982313|ref|NP_032212.2| general transcription factor II H, polypeptide 1 [Mus musculus], gi|128...
568.0 [0..6] [583..11]
gi|89273970, gi|... - gi|89273970|emb|CAJ81309.1| general transcription factor IIH, polypeptide 1, 62kDa [Xenopus tropical...
gi|55742100 - ref|NP_001006921.1| general transcription factor IIH, polypeptide 1, 62kDa [Xenopus tropicalis]
565.0 [0..6] [583..11]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGGQIEKLV KYKSTVKDPG TPGFLRIREG MLLFVPNDPK SDSKLKVLTQ NIKSQKYTKE  60
   61 GSNKPPWLNL TNKQAKSHIF EFENYPDMHA CRDFITKALA KCELEPNKSV VST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.09691
Match: 1pfjA
Description: Solution structure of the N-terminal PH/PTB domain of the TFIIH P62 subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [114-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSEQLSIKEL ELRFKLLREN SELQRLHKQF VESKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.09691
Match: 2diiA
Description: No description for 2diiA was found.

Predicted Domain #3
Region A:
Residues: [149-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTEDEFWATR KKLLGKDSIR KSKQQLGLKS MMVSGIKPST DGRTNRVTFN LTPEIIFQIF  60
   61 AEKPAVRQAF INYVPSKMTE KDFWTKYFRA EYLYSTKNTA VAAAEAAEDE ELAVFLKPDE 120
  121 ILARETRHKI RRVDPTLDME ADQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.78
Match: 1x3aA
Description: Solution structure of the BSD domain of human Synapse associated protein 1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [292-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDDYTHLMDH GIQRDGTMDV VEPQNDQFKR SLLQDLNRHA AVVLEGRSID VESEDTRIVA  60
   61 EALTR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.491 a.189.1 Description not found.
View Download 0.482 a.3.1 Cytochrome c
View Download 0.442 a.65.1 Annexin
View Download 0.442 a.65.1 Annexin
View Download 0.408 a.189.1 Description not found.
View Download 0.406 d.169.1 C-type lectin-like
View Download 0.341 d.169.1 C-type lectin-like
View Download 0.333 a.3.1 Cytochrome c

Predicted Domain #5
Region A:
Residues: [357-486]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKQVSKADGE TTKDANQERL ERMSRVAGME DLQAPQNFPL APLSIKDPRD YFESQQGNVL  60
   61 NVPRGAKGLK RNVHEAYGLL KESILEIRAT GLSDPLIKPE VSFEVFSSLT RTIATAKNIN 120
  121 GKNPRESFLD 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.636 N/A N/A a.29.16 Description not found.
View Download 0.578 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.523 N/A N/A a.29.13 Description not found.
View Download 0.492 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.492 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.489 N/A N/A a.29.13 Description not found.
View Download 0.469 N/A N/A a.29.13 Description not found.
View Download 0.468 N/A N/A a.7.8 GAT domain
View Download 0.405 N/A N/A a.7.1 Spectrin repeat
View Download 0.367 N/A N/A a.7.1 Spectrin repeat

Predicted Domain #6
Region A:
Residues: [487-591]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLPKSTKDEV LHHWTSIQEL LKHFWSSYPI TTTYLHTKVG KLKDAMSNTY SKLEAMKESV  60
   61 QSDLRHQVSL LVRPMQQALD AAFHHYEVDL QRRTAKSGER PNGYV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.986 N/A N/A a.8.11 Description not found.
View Download 0.984 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.979 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.979 N/A N/A a.7.16 Description not found.
View Download 0.977 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.976 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.974 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.974 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.971 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.970 N/A N/A a.47.2 t-snare proteins


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