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View Structure Prediction Details

Protein: gi|36786133, gi|...
Organism: Photorhabdus luminescens subsp. laumondii TTO1
Length: 283 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|36786133, gi|....

Description E-value Query
Range
Subject
Range
gi|238728942, gi... - gi|77980020|ref|ZP_00835435.1| COG0846: NAD-dependent protein deacetylases, SIR2 family [Yersinia in...
301.0 [0..1] [279..1]

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Predicted Domain #1
Region A:
Residues: [1-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVRRRLSRL GRLRKVKRLR HQRFRSRIFY RDNRLALNMK KPYIVVLTGA GISAESGIRT  60
   61 FRSSDGLWEE HRVEDVATPE GFQKDPELVQ AFYNARRHQL QQSEIKPNVA HYALAALEHE 120
  121 LGDNFLLITQ NIDDLHERAG SYRTVHMHGE LFKIRCCQSG QVFEWTDDLT TDERCHCCQF 180
  181 PSPLRPHVVW FGEMPLEMEQ IYSALAQADI FIAIGTSGHV YPAAGFVHEA KLAGAHTVEL 240
  241 NLEPSQVESL FDEKHYGPAS KIVDEYARRL IDSIKEFKAD LTQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.30103
Match: 1s5pA
Description: Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Eschericia coli.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NAD+ ADP-ribosyltransferase activity 4.03377448635905 bayes_pls_golite062009
NAD-dependent histone deacetylase activity 3.62931364715038 bayes_pls_golite062009
NAD-dependent protein deacetylase activity 3.62931364715038 bayes_pls_golite062009
histone deacetylase activity 3.33234624338308 bayes_pls_golite062009
protein deacetylase activity 3.3158908416347 bayes_pls_golite062009
deacetylase activity 2.93661150106825 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1.75247092617964 bayes_pls_golite062009
transcription regulator activity 1.35219834199205 bayes_pls_golite062009
catalytic activity 1.1096503360938 bayes_pls_golite062009
nucleic acid binding 0.798062126041325 bayes_pls_golite062009
DNA binding 0.76914567174665 bayes_pls_golite062009
binding 0.725903081591757 bayes_pls_golite062009
NAD(P)+-protein-arginine ADP-ribosyltransferase activity 0.6957216362751 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.59989665970892 bayes_pls_golite062009
transcription repressor activity 0.535572217873276 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle