YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227082231, gi...
Organism:	Vibrio cholerae M66-2
Length:	150 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227082231, gi....

Description	E-value	Query Range	Subject Range
tr\|A0A085TPC6\|A0... - Ferric uptake regulation protein OS=Vibrio cholerae GN=fur PE=4 SV=1 gi\|49387485 - gi\|49387485\|dbj\|BAD24855.1\| ferric uptake regulator [Vibrio mimicus]	183.0	[0..1]	[150..1]
FUR_VIBC3 - Ferric uptake regulation protein OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa... gi\|121727219, gi... - gi\|75816912\|ref\|ZP_00747370.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Vibrio cholerae V52], ... gi\|282080, gi\|155167 - pir\|\|A42282 ferric uptake regulator - Vibrio cholerae, gi\|155167\|gb\|AAA27519.1\| fur [Vibrio cholera...	182.0	[0..1]	[150..1]
gi\|88792643, gi\|... - gi\|90192401\|gb\|AAY28416.2\| ferric uptake regulator [Vibrio alginolyticus], gi\|88792643\|gb\|ABD52297.1... gi\|91225929, gi\|... - gi\|91225929\|ref\|ZP_01260898.1\| ferric uptake regulator [Vibrio alginolyticus 12G01], gi\|91189579\|gb\|...	180.0	[0..1]	[150..1]
FUR_VIBAN - Ferric uptake regulation protein OS=Vibrio anguillarum GN=fur PE=1 SV=1 FUR_VIBA7 - Ferric uptake regulation protein OS=Vibrio anguillarum (strain ATCC 68554 / 775) GN=fur PE=1 SV=1	179.0	[0..1]	[150..1]
gi\|37197941, gi\|... - gi\|37679198\|ref\|NP_933807.1\| ferric uptake regulator [Vibrio vulnificus YJ016], gi\|37197941\|dbj\|BAC9...	178.0	[0..1]	[149..19]
FUR_VIBPA - Ferric uptake regulation protein OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=... FUR_VIBPA - Ferric uptake regulation protein OS=Vibrio parahaemolyticus GN=fur PE=3 SV=1	177.0	[0..1]	[150..1]
FUR_SHIFL - Ferric uptake regulation protein OS=Shigella flexneri GN=fur PE=3 SV=1 gi\|24050852, gi\|... - gi\|24112031\|ref\|NP_706541.1\| ferric uptake regulator [Shigella flexneri 2a str. 301], gi\|24050852\|gb...	176.0	[0..1]	[149..1]
FUR_KLEPN - Ferric uptake regulation protein OS=Klebsiella pneumoniae GN=fur PE=3 SV=2	176.0	[0..1]	[144..1]
gi\|194420938, gi... - gi\|83584543\|ref\|ZP_00923217.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli 101-1... gi\|187730107, gi... - gi\|75175174\|ref\|ZP_00695495.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Shigella boydii BS512]... gi\|83569133, gi\|... - gi\|83569133\|ref\|ZP_00920593.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Shigella dysenteriae 1... gi\|194430648, gi... - gi\|75207978\|ref\|ZP_00708406.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli B171]... gi\|193071731, gi... - gi\|75214659\|ref\|ZP_00713176.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli E1100... gi\|157156224, gi... - gi\|75189711\|ref\|ZP_00702978.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli E2437... gi\|75194850, gi\|... - gi\|75194850\|ref\|ZP_00704920.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli HS], ... EG10359 - ferric iron uptake regulon transcriptional repressor; autorepressor / Ferric iron uptake global tran... gi\|227838428, gi... - gi\|227884342\|ref\|ZP_04002147.1\| ferric uptake regulator [Escherichia coli 83972], gi\|227838428\|gb\|EE... gi\|226898558, gi... - gi\|237707348\|ref\|ZP_04537829.1\| negative regulator [Escherichia sp. 3_2_53FAA], gi\|226898558\|gb\|EEH8... gi\|238860938, gi... - gi\|238899949\|ref\|YP_002925745.1\| DNA-binding transcriptional dual regulator of siderophore biosynthe... gi\|251784173, gi... - gi\|251784173\|ref\|YP_002998477.1\| hypothetical protein B21_00631 [Escherichia coli BL21], gi\|24237644... gi\|253976846, gi... - gi\|254287539\|ref\|YP_003053287.1\| ferric uptake regulator [Escherichia coli BL21(DE3)], gi\|253976846\|... gi\|253972652, gi... - gi\|254160751\|ref\|YP_003043859.1\| ferric uptake regulator [Escherichia coli B str. REL606], gi\|253972... gi\|254591235, gi... - gi\|254791835\|ref\|YP_003076672.1\| DNA-binding transcriptional dual regulator of siderophore biosynthe... gi\|217325583, gi... - gi\|217325583\|ref\|ZP_03441667.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. TW14... gi\|215485714, gi... - gi\|215485714\|ref\|YP_002328145.1\| ferric uptake regulator [Escherichia coli O127:H6 str. E2348/69], g... gi\|218553216, gi... - gi\|218553216\|ref\|YP_002386129.1\| ferric uptake regulator [Escherichia coli IAI1], gi\|218359984\|emb\|C... gi\|218549749, gi... - gi\|218549749\|ref\|YP_002383540.1\| ferric uptake regulator [Escherichia fergusonii ATCC 35469], gi\|218... gi\|218426053, gi... - gi\|218688489\|ref\|YP_002396701.1\| ferric uptake regulator [Escherichia coli ED1a], gi\|218426053\|emb\|C... gi\|218557611, gi... - gi\|218557611\|ref\|YP_002390524.1\| ferric uptake regulator [Escherichia coli S88], gi\|218364380\|emb\|CA... gi\|218369023, gi... - gi\|218699037\|ref\|YP_002406666.1\| ferric uptake regulator [Escherichia coli IAI39], gi\|218369023\|emb\|... FUR_ECOL6 - Ferric uptake regulation protein OS=Escherichia coli O6 GN=fur PE=3 SV=1 gi\|218694111, gi... - gi\|218694111\|ref\|YP_002401778.1\| ferric uptake regulator [Escherichia coli 55989], gi\|218350843\|emb\|... gi\|170767903, gi... - gi\|170767903\|ref\|ZP_02902356.1\| ferric uptake regulation protein [Escherichia albertii TW07627], gi\|... gi\|170518320, gi... - gi\|170680602\|ref\|YP_001742794.1\| ferric uptake regulation protein [Escherichia coli SMS-3-5], gi\|170... gi\|208805963, gi... - gi\|208805963\|ref\|ZP_03248300.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC42... gi\|195939407 - gi\|195939407\|ref\|ZP_03084789.1\| ferric uptake regulator [Escherichia coli O157:H7 str. EC4024] gi\|208823218, gi... - gi\|208823218\|ref\|ZP_03263536.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC40... gi\|208731907, gi... - gi\|208815259\|ref\|ZP_03256438.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC40... gi\|209911195, gi... - gi\|209917936\|ref\|YP_002292020.1\| ferric uptake regulator [Escherichia coli SE11], gi\|209911195\|dbj\|B... gi\|209160587, gi... - gi\|209399187\|ref\|YP_002269311.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4... gi\|117622891, gi... - gi\|117622891\|ref\|YP_851804.1\| ferric uptake regulator [Escherichia coli APEC O1], gi\|115512015\|gb\|AB... gi\|124499710, gi... - gi\|124529707\|ref\|ZP_01700614.1\| ferric uptake regulator, Fur family [Escherichia coli B], gi\|1244997... gi\|218431104, gi... - gi\|218704007\|ref\|YP_002411526.1\| ferric uptake regulator [Escherichia coli UMN026], gi\|218431104\|emb... gi\|189363492, gi... - gi\|189363492\|gb\|EDU81911.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4486],... gi\|168765346, gi... - gi\|189364895\|gb\|EDU83311.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4501],... gi\|189002775, gi... - gi\|189002775\|gb\|EDU71761.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4076],... gi\|168777911, gi... - gi\|187766943\|gb\|EDU30787.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4196],... gi\|168803045, gi... - gi\|189375199\|gb\|EDU93615.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC508], ... gi\|189373644, gi... - gi\|189373644\|gb\|EDU92060.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC869], ... gi\|169888187, gi... - gi\|170080352\|ref\|YP_001729672.1\| DNA-binding transcriptional dual regulator of siderophore biosynthe... gi\|169755899, gi... - gi\|170020971\|ref\|YP_001725925.1\| ferric uptake regulator [Escherichia coli ATCC 8739], gi\|169755899\|... FUR_ECOL6 - Ferric uptake regulation protein OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=f... FUR_ECO57 - Ferric uptake regulation protein OS=Escherichia coli O157:H7 GN=fur PE=3 SV=1 gi\|30040387, gi\|... - gi\|30062142\|ref\|NP_836313.1\| ferric uptake regulator [Shigella flexneri 2a str. 2457T], gi\|30040387\|... gi\|15800386, gi\|... - gi\|15800386\|ref\|NP_286398.1\| ferric uptake regulator [Escherichia coli O157:H7 EDL933], gi\|12513585\|... gi\|189355785, gi... - gi\|189355785\|gb\|EDU74204.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4401],... EG10359 - ferric iron uptake regulon transcriptional repressor; autorepressor / Ferric iron uptake global tran... gi\|188013595, gi... - gi\|188013595\|gb\|EDU51717.1\| ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4113],... FUR_ECOLI - Ferric uptake regulation protein (Ferric uptake regulator) - Escherichia coli gi\|91071299, gi\|... - gi\|91209725\|ref\|YP_539711.1\| ferric uptake regulator [Escherichia coli UTI89], gi\|91071299\|gb\|ABE061... gi\|13360172, gi\|... - gi\|15829968\|ref\|NP_308741.1\| ferric uptake regulator [Escherichia coli O157:H7 str. Sakai], gi\|13360... gi\|110342494, gi... - gi\|110640902\|ref\|YP_668630.1\| ferric uptake regulator [Escherichia coli 536], gi\|110342494\|gb\|ABG687... gi\|110804680, gi... - gi\|110804680\|ref\|YP_688200.1\| ferric uptake regulator [Shigella flexneri 5 str. 8401], gi\|110614228\|... gi\|1651290, gi\|8... - gi\|89107541\|ref\|AP_001321.1\| DNA-binding transcriptional dual regulator [Escherichia coli str. K-12 ... gi\|75258591, gi\|... - gi\|75258591\|ref\|ZP_00729998.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli E22],... gi\|75511083, gi\|... - gi\|75511083\|ref\|ZP_00733815.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli 53638... gi\|191169350, gi... - gi\|75227331\|ref\|ZP_00714114.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli B7A],... gi\|190905744, gi... - gi\|75237566\|ref\|ZP_00721597.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Escherichia coli F11],... gi\|82543117, gi\|... - gi\|82543117\|ref\|YP_407064.1\| ferric uptake regulator [Shigella boydii Sb227], gi\|81244528\|gb\|ABB6523... gi\|74311211, gi\|... - gi\|74311211\|ref\|YP_309630.1\| ferric uptake regulator [Shigella sonnei Ss046], gi\|73854688\|gb\|AAZ8739... gi\|82775958, gi\|... - gi\|82775958\|ref\|YP_402305.1\| ferric uptake regulator [Shigella dysenteriae Sd197], gi\|81240106\|gb\|AB...	176.0	[0..1]	[149..1]

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Predicted Domain #1

Region A:
Residues: [1-150]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDNNQALKD AGLKVTLPRL KILEVLQQPE CQHISAEELY KKLIDLGEEI GLATVYRVLN  60
   61 QFDDAGIVTR HHFEGGKSVF ELSTQHHHDH LVCLDCGEVI EFSDDVIEQR QKEIAAKYNV 120
  121 QLTNHSLYLY GKCGSDGSCK DNPNAHKPKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.69897
Match:	1mzbA
Description:	Ferric uptake regulator
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.51306541310201	bayes_pls_golite062009
DNA binding	4.12876602944304	bayes_pls_golite062009
nucleic acid binding	4.12610640813616	bayes_pls_golite062009
transcription factor activity	3.36245551077648	bayes_pls_golite062009
binding	2.88885372623841	bayes_pls_golite062009
sequence-specific DNA binding	1.57171040630767	bayes_pls_golite062009
transcription activator activity	1.46816740214642	bayes_pls_golite062009
transcription repressor activity	1.35320462873179	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.77269240913386	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: