| Protein: | DIN7_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 430 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIN7_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..430] | [1..430] |
|
|
2.0E-86 | [1..390] | [1..379] |
|
|
1.0E-84 | [1..409] | [1..423] |
|
|
2.0E-83 | [1..409] | [1..423] |
|
|
5.0E-83 | [1..367] | [1..358] |
|
|
2.0E-82 | [1..367] | [1..358] |
|
|
2.0E-80 | [1..387] | [1..379] |
|
|
4.0E-80 | [1..373] | [1..361] |
|
Region A: Residues: [1-349] |
1 11 21 31 41 51
| | | | | |
1 MGIPGLLPQL KRIQKQVSLK KYMYQTLAID GYAWLHRASC ACAFELVMNK PTNKYLQFFI 60
61 KRLQLLKRLK IKPYIVFDGD SLFVKNHTET RRRKKRLENE MIAKKLWSAG NRYNAMEYFQ 120
121 KSVDITPEMA KCIIDYCKLH SIPYIVAPFE ADPQMVYLEK MGLIQGIISE DSDLLVFGCK 180
181 TLITKLNDQG KALEISKDDF SALPENFPLG ELSEQQFRNL VCLAGCDYTS GIWKVGVVTA 240
241 MKIVKRYSEM KDILIQIERT EKLCFSKAFK QQVEFANYAF QYQRVFCPLS NQITTLNNIP 300
301 KAVTNSHAEI IKIMKCIGSV VERGSGVRKD VINTKNIDHK VHEMIAKGE
|
| Detection Method: |  |
| Confidence: | 164.0103 |
| Match: | 1a76__ |
| Description: | Flap endonuclease-1 (Fen-1 nuclease) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| flap endonuclease activity | 3.67578601858151 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 3.29138075959109 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 3.25110450559975 | bayes_pls_golite062009 |
| exonuclease activity | 3.08589196968812 | bayes_pls_golite062009 |
| 5'-3' exonuclease activity | 2.82147159438565 | bayes_pls_golite062009 |
| nuclease activity | 2.11339581411994 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 2.0005433655378 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 1.9833086883205 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.91303769651266 | bayes_pls_golite062009 |
| 5'-3' exodeoxyribonuclease activity | 1.87664153967776 | bayes_pls_golite062009 |
| double-stranded DNA specific exodeoxyribonuclease activity | 1.68933217523176 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.6357876066979 | bayes_pls_golite062009 |
| hydrolase activity | 1.55146225298048 | bayes_pls_golite062009 |
| 5'-flap endonuclease activity | 1.44561869581238 | bayes_pls_golite062009 |
| endonuclease activity | 1.40552749109921 | bayes_pls_golite062009 |
| catalytic activity | 1.37534898662234 | bayes_pls_golite062009 |
| single-stranded DNA specific exodeoxyribonuclease activity | 1.27080587821961 | bayes_pls_golite062009 |
| DNA binding | 1.0824699122398 | bayes_pls_golite062009 |
| binding | 1.04616076007281 | bayes_pls_golite062009 |
| nucleic acid binding | 1.03274122519509 | bayes_pls_golite062009 |
| damaged DNA binding | 0.98172679437643 | bayes_pls_golite062009 |
| single-stranded DNA specific 5'-3' exodeoxyribonuclease activity | 0.807459896574807 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.71603644615457 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.620251812982006 | bayes_pls_golite062009 |
| protein binding | 0.236485289446406 | bayes_pls_golite062009 |
|
Region A: Residues: [350-430] |
1 11 21 31 41 51
| | | | | |
1 LHPVDMASKL INRERKLKAR KLFKVGLLGG ESNSFNKKVE QPLVDTQDVL SERENSLDNK 60
61 NASSIYMTSP AAISGTVPSI F
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.566 | a.3.1 | Cytochrome c |
| View | Download | 0.535 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.672 | a.39.1 | EF-hand |
| View | Download | 0.499 | a.2.3 | Chaperone J-domain |
| View | Download | 0.498 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.463 | a.4.3 | ARID-like |
| View | Download | 0.435 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.394 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.387 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.361 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.341 | d.94.1 | HPr-like |
| View | Download | 0.326 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.318 | a.3.1 | Cytochrome c |
| View | Download | 0.310 | a.77.1 | DEATH domain |
| View | Download | 0.303 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.302 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.292 | a.46.1 | Methionine synthase domain |
| View | Download | 0.278 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.277 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.270 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.264 | a.77.1 | DEATH domain |
| View | Download | 0.263 | a.3.1 | Cytochrome c |
| View | Download | 0.249 | a.179.1 | Replisome organizer (g39p helicase loader/inhibitor protein) |
| View | Download | 0.235 | a.2.7 | tRNA-binding arm |
| View | Download | 0.210 | a.60.8 | HRDC-like |
| View | Download | 0.209 | a.4.5 | "Winged helix" DNA-binding domain |
