YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25389201
Organism:	Streptococcus pneumoniae
Length:	394 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25389201.

Description	E-value	Query Range	Subject Range
gi\|15903454, gi\|... - gi\|15903454\|ref\|NP_359004.1\| cation efflux family protein [Streptococcus pneumoniae R6], gi\|15459063... gi\|116077747, gi... - gi\|116517171\|ref\|YP_816844.1\| cation efflux family protein [Streptococcus pneumoniae D39], gi\|116077... gi\|25509049 - pir\|\|B98048 conserved hypothetical protein spr1411 [imported] - Streptococcus pneumoniae (strain R6)	365.0	[0..1]	[394..1]
gi\|76585756, gi\|... - gi\|76798887\|ref\|ZP_00781094.1\| cation efflux family protein [Streptococcus agalactiae 18RS21], gi\|76... gi\|22534174, gi\|... - gi\|22537304\|ref\|NP_688155.1\| cation efflux family protein [Streptococcus agalactiae 2603V/R], gi\|225... gi\|23095686, gi\|... - gi\|25011262\|ref\|NP_735657.1\| hypothetical protein gbs1213 [Streptococcus agalactiae NEM316], gi\|2309...	331.0	[0..1]	[393..1]
gi\|77174716, gi\|... - gi\|77406675\|ref\|ZP_00783717.1\| cation efflux family protein [Streptococcus agalactiae H36B], gi\|7717...	330.0	[0..1]	[393..1]
gi\|76788549, gi\|... - gi\|76788549\|ref\|YP_329849.1\| cation diffusion facilitator (CDF) family protein [Streptococcus agalac...	330.0	[0..1]	[393..1]
gi\|77171659, gi\|... - gi\|77409731\|ref\|ZP_00786391.1\| cation efflux family protein [Streptococcus agalactiae COH1], gi\|7717...	330.0	[0..1]	[393..1]
gi\|77412605, gi\|... - gi\|77412605\|ref\|ZP_00788890.1\| cation efflux family protein [Streptococcus agalactiae CJB111], gi\|77...	327.0	[0..5]	[393..1]
gi\|77159077, gi\|... - gi\|77414876\|ref\|ZP_00790986.1\| cation efflux family protein [Streptococcus agalactiae 515], gi\|77159...	322.0	[0..6]	[393..1]
gi\|24377555, gi\|... - gi\|24379606\|ref\|NP_721561.1\| putative cation efflux transporter [Streptococcus mutans UA159], gi\|243...	320.0	[0..1]	[391..1]
gi\|94990603, gi\|... - gi\|94990603\|ref\|YP_598703.1\| cobalt-zinc-cadmium resistance protein czcD [Streptococcus pyogenes MGA...	314.0	[0..3]	[391..4]
gi\|28811265, gi\|... - gi\|28896015\|ref\|NP_802365.1\| putative cation efflux system protein [Streptococcus pyogenes SSI-1], g... gi\|21904638, gi\|... - gi\|21910440\|ref\|NP_664708.1\| putative cation efflux system protein [Streptococcus pyogenes MGAS315],...	312.0	[0..3]	[391..4]

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Predicted Domain #1

Region A:
Residues: [1-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQSISNLKL AERGAIISIS TYLILSAAKL AAGHLLHSSS LVADGFNNVS DIIGNVALLI  60
   61 GIRMARQPAD RDHRFGHWKI EDLASLITSI IMFYVGFDVL RDTIQKILSR EETVIDPLGA 120
  121 TLGIISAAIM FVVYLYNTRL SKKSNSNALK AAAKDNLSDA VTSLGTAIAI LASSFNYPIV 180
  181 DKLVAIIITF FILKTAYDIF IESSFSLSDG FDDRLLEDYQ KAIMEIPKIS KVKSQRGRTY 240
  241 GSNIYLDITL EMNPDLSVFE SHEIADQVES MLEERFGVFD TDVHIEPAPI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.0
Match:	2qfiA
Description:	No description for 2qfiA was found.

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	4.5307404935943	bayes_pls_golite062009
ion transmembrane transporter activity	4.4634224995221	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.1916987544196	bayes_pls_golite062009
transporter activity	2.72282838578572	bayes_pls_golite062009
transmembrane transporter activity	2.61155472577391	bayes_pls_golite062009
substrate-specific transporter activity	2.37288341875523	bayes_pls_golite062009
efflux transmembrane transporter activity	1.43383523050563	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.253156897715141	bayes_pls_golite062009
binding	0.112542057149574	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0523266677042269	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [291-394]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEDEILDNVY KKLLMREQLI DQGNQLEELL TDDFVYIRQD GEQMDKEAYK TKKELNSAIK  60
   61 DIQITSISQK TKLICYELDG IIHTSIWRRH ETWQNIFHQE TKKE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.77
Match:	2r4iA
Description:	No description for 2r4iA was found.

Predicted functions:

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	0.909402729936813	bayes_pls_golite062009
binding	0.682592304899812	bayes_pls_golite062009
protein binding	0.218842901565592	bayes_pls_golite062009
transporter activity	0.215781707476951	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: