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View Structure Prediction Details

Protein: CG4673-PA
Organism: Drosophila melanogaster
Length: 652 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4673-PA.

Description E-value Query
Range
Subject
Range
CG4673-PD, CG4673-PB - This gene is referred to in FlyBase by the symbol Dmel\CG4673 (CG4673, FBgn0039348). It is a protein...
896.0 [0..32] [652..4]

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Predicted Domain #1
Region A:
Residues: [1-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACAPLLLEQ FIYKKRNFAY AFVRHRLFVL CKQSLIRVQS AEGIKRIEIS PKSNLKHLYD  60
   61 SVQNALKVDG FGLFKERNFL TELQASGSQL VGTSLRHGDM VYLKQMAGTS SRRTSTTVLD 120
  121 SQAFKTSTIS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.30103
Match: 1wf9A
Description: Solution structure of a novel beta-grasp fold like domain of Hypothetical protein (Arabidopsis thaliana)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 6.3238498800949 bayes_pls_golite062009
ubiquitin-protein ligase activity 5.759996473289 bayes_pls_golite062009
acid-amino acid ligase activity 5.32190918602578 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 4.23828791893907 bayes_pls_golite062009
binding 2.5881743465274 bayes_pls_golite062009
ligase activity 2.25858205355159 bayes_pls_golite062009
protein binding 1.76858817153382 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
signal transducer activity 0.5176352635445 bayes_pls_golite062009
molecular transducer activity 0.5176352635445 bayes_pls_golite062009
nucleic acid binding 0.383121378043805 bayes_pls_golite062009
cytoskeletal protein binding 0.366426020658587 bayes_pls_golite062009
transcription regulator activity 0.273912905624139 bayes_pls_golite062009
DNA binding 0.0840213088061073 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [131-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNSARPSFN VIEDDVDQAL SKADGTIKRE RDSKLCHHNA NGRCVHCSAL EPYDESYLKE  60
   61 HNIKHLSFHS YIRKQTSGMD QG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 42.19382
Match: PF05020.6
Description: No description for PF05020.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [213-583]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYFVFDDINC RIKPGCREHP PWPKGICSKC QPSAITLNRQ TYRHVDNVMF ENTKIVERFL  60
   61 NYWRTTGHQR MGYLYGTYEQ HTDVPLGIRA KVAAIYEPPQ ESTRDSINIQ PDEFADDVDA 120
  121 VASALGLKKI GWIFTDLITD DASIGTVKQI RGIESHFITA QECITAGELQ NRHPNPCKYA 180
  181 SNGVFGSKFV TICVTGDKTK QVHMEGYAVS AQCMALVRDN CLIPTKDAPE LGYVRESTDK 240
  241 QYVPDVFYKE KDLYGNEVQR LARPLPVEYL LVDVPASTPL QPIYTFTEYD KRQPFPIENR 300
  301 YIDGHLQDFN ALSCYLSAWG EEEFLEAISD FHLLVYLYKM DMLPLRQHMG PLLEAVRTKN 360
  361 PNQAAQFKVV D

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.8
Match: 2og4A
Description: No description for 2og4A was found.

Predicted Domain #4
Region A:
Residues: [584-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VWKLLESLIQ ASSGGSGGTT SYPSGGASAS AGASGSEAMD LDANTWTCNH CTFINRGELT  60
   61 SCEICSLPR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle