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Protein Overview: CG4673-PA

General Information:
Name(s) found: CG4673-PA / FBpp0084267 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4673 (CG4673, FBgn0039348). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21436735..21450382. It has the cytological map location 96E4-96E6. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of nuclear pore. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 652 amino acids

    Gene Ontology:
    Cellular Component: nuclear pore [ISS]
    Biological Process: NONE FOUND
    Molecular Function: zinc ion binding [IEA]
    structural constituent of nuclear pore [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACAPLLLEQ FIYKKRNFAY AFVRHRLFVL CKQSLIRVQS AEGIKRIEIS PKSNLKHLYD  60
   61 SVQNALKVDG FGLFKERNFL TELQASGSQL VGTSLRHGDM VYLKQMAGTS SRRTSTTVLD 120
  121 SQAFKTSTIS NPNSARPSFN VIEDDVDQAL SKADGTIKRE RDSKLCHHNA NGRCVHCSAL 180
  181 EPYDESYLKE HNIKHLSFHS YIRKQTSGMD QGKYFVFDDI NCRIKPGCRE HPPWPKGICS 240
  241 KCQPSAITLN RQTYRHVDNV MFENTKIVER FLNYWRTTGH QRMGYLYGTY EQHTDVPLGI 300
  301 RAKVAAIYEP PQESTRDSIN IQPDEFADDV DAVASALGLK KIGWIFTDLI TDDASIGTVK 360
  361 QIRGIESHFI TAQECITAGE LQNRHPNPCK YASNGVFGSK FVTICVTGDK TKQVHMEGYA 420
  421 VSAQCMALVR DNCLIPTKDA PELGYVREST DKQYVPDVFY KEKDLYGNEV QRLARPLPVE 480
  481 YLLVDVPAST PLQPIYTFTE YDKRQPFPIE NRYIDGHLQD FNALSCYLSA WGEEEFLEAI 540
  541 SDFHLLVYLY KMDMLPLRQH MGPLLEAVRT KNPNQAAQFK VVDVWKLLES LIQASSGGSG 600
  601 GTTSYPSGGA SASAGASGSE AMDLDANTWT CNHCTFINRG ELTSCEICSL PR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] PSI-BLAST 14.30103 Solution structure of a novel beta-grasp fold like domain of Hypothetical protein (Arabidopsis thaliana)
    2 View Details [131..212] Pfam 42.19382 No description for PF05020.6 was found. No confident structure predictions are available.
    3 View Details [213..583] FFAS03 2.8 No description for 2og4A was found.
    4 View Details [584..652] MSA 10.041995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  6.3238498800949 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  5.759996473289 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.32190918602578 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.23828791893907 bayes_pls_golite062009
  • binding
    		•  2.5881743465274 bayes_pls_golite062009
  • ligase activity
    		•  2.25858205355159 bayes_pls_golite062009
  • protein binding
    		•  1.76858817153382 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
  • signal transducer activity
    		•  0.5176352635445 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.5176352635445 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.383121378043805 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.366426020658587 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.273912905624139 bayes_pls_golite062009
  • DNA binding
    		•  0.0840213088061073 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle