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View Structure Prediction Details

Protein: egl-13
Organism: Caenorhabditis elegans
Length: 422 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-13.

Description E-value Query
Range
Subject
Range
egl-13 - status:Confirmed UniProt:Q23045 protein_id:AAB04597.2
290.0 [0..1] [422..49]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDTPNPAGS PHDASIKSSS STISDHTSTS ATTGISDFPD ILAQTEHGCS VLIDGNHLRE  60
   61 IINSVDTQDG KQDLLSDVIR QLTSIKERL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [90-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNDESPVKDD LKEDPDDMSP MLHAGNFDSE MLLRQHELMQ HQQQQMIIAN MLKATQSLPL  60
   61 LFNGGLNYEA ILNNPVLNAT IAGHLPNPLA SNISLLQKSI SAKLAAAGNM QTVEKVETPL 120
  121 NLSKDTPSPT AIPQSPLSGF RLPYSLGTNY GSDGQLFNNC SPNSSGKSTP GNTSVTSEVA 180
  181 TPRPQA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.13364477654991 bayes_pls_golite062009
DNA binding 1.53868224871484 bayes_pls_golite062009
transcription regulator activity 1.08780465158402 bayes_pls_golite062009
nucleic acid binding 0.818311652354687 bayes_pls_golite062009
transcription factor activity 0.53515597626729 bayes_pls_golite062009
protein binding 0.436111251185035 bayes_pls_golite062009
sequence-specific DNA binding 0.42024807191387 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSPNHIKRPM NAFMVWARDE RRKILKAYPD MHNSNISKIL GSRWKGMSNS EKQPYYEEQS  60
   61 RLSKLHMEQH PDYRYRPRPK RTCVIDGKKV RVNEYKTIMK TKKDLMWGDE PGFSQPSDLQ 120
  121 MDLASHVNLL NDLTQHHHQS HLLQTAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.221849
Match: 2gzkA
Description: No description for 2gzkA was found.

Predicted functions:

Term Confidence Notes
binding 2.13364477654991 bayes_pls_golite062009
DNA binding 1.53868224871484 bayes_pls_golite062009
transcription regulator activity 1.08780465158402 bayes_pls_golite062009
nucleic acid binding 0.818311652354687 bayes_pls_golite062009
transcription factor activity 0.53515597626729 bayes_pls_golite062009
protein binding 0.436111251185035 bayes_pls_golite062009
sequence-specific DNA binding 0.42024807191387 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle