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View Structure Prediction Details

Protein: pkd-2
Organism: Caenorhabditis elegans
Length: 716 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pkd-2.

Description E-value Query
Range
Subject
Range
gi|50749558 - gi|50749558|ref|XP_426509.1| PREDICTED: similar to Polycystic kidney disease 2-like 1 protein (Polyc...
483.0 [0..14] [716..394]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYGAADERW ANPPQPVAAA EHGPSFDHSM VSEEYEHDKK KNPAQKEGIS FSQALLASGH  60
   61 EKSDGKIKLT ARSFMEVGGY AVFLIVLVYV AFAQNSIQSY YYSKVMSDLF VASTGASGAP 120
  121 AFGSCTSMDN IWDWLSQVLI PGIYWTETSN STDNENMI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [159-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YYENRLLGEP RIRMLKVTND SCTVMKSFQR EIKECFANYE EKLEDKTMVG DGSVDAFIYA  60
   61 TAKELENLKT VGTIASYGGG GFVQRLPVAG STEAQSAIAT LKANRWIDRG SRAIIVDFAL 120
  121 YNANINLFCV VKLLFELPAS GGVITTPKLM TYDLLTYQTS GGTRMMIFEG IFCGFILYFI 180
  181 FEELFAIGRH RLHYLTQFWN LVDVVLLGFS VATIILSVNR TKTGVNRVNS VIENGLTNAP 240
  241 FDDVTSSENS YLNIKACVVF VAWVKVFKFI SVNKTMSQLS STLTRSAKDI GGFAVMFAVF 300
  301 FFAFAQFGYL CFGTQIADYS NLYNSAFALL RLILGDFNFS ALESCNRFFG PAFFIAYVFF 360
  361 VSFILLNMFL AIINDSYVEV KAELARKKDG EGILDWFMNK VRGLTKRGKR PDAPGEDATY 420
  421 EDYKLMLYRA GYAEKDINEA FTRFNVTSMT EHVPEKVAED IADEVARMTE QKRNYM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.045757
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [635-716]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENHRDYANLN RRVDQMQESV FSIVDRIEGV NATLQTIEKQ RVQQQDGGNL MDLSALLTNQ  60
   61 VRNRESAARR PTITSIADKK EE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle