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View Structure Prediction Details

Protein: SIP4
Organism: Saccharomyces cerevisiae
Length: 829 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIP4.

Description E-value Query
Range
Subject
Range
SIP4 - C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) ...
SIP4_YEAST - Protein SIP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIP4 PE=3 SV=1
0.0 [1..829] [1..829]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..829] [1..829]
gi|6901427 - gi|6901427|emb|CAB71797.1| pathway-specific nitrogen regulator [Tolypocladium inflatum]
4.0E-74 [15..386] [39..432]
gi|168849 - gi|168849|gb|AAA33602.1| pathway-specific regulatory protein [Neurospora crassa]
4.0E-67 [15..386] [22..418]
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 ...
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans GN=nirA PE=4 SV=1
9.0E-53 [4..402] [3..409]
SPAC139.03 - transcription factor, zf-fungal binuclear cluster type
YII3_SCHPO - Uncharacterized transcriptional regulatory protein C139.03 OS=Schizosaccharomyces pombe (strain 972 ...
5.0E-42 [25..302] [2..305]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRKYGRSY SLDDTDSCSN KVLIVPTGQS SSNAITDFSV RKAHACDRCR LKKIKCDGLK  60
   61 PNCSNCAKID FPCKTSDKLS RRGLPKGYTE LLEKEVVRLT NMNASSSANA NSNLPFINDT 120
  121 FYCFDNYNTQ SENQRFLGHL TWNILTNTFP TQKAVVFTDD RNNIDLQLQL LTNFLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 105.30103
Match: 1pyiA_
Description: PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
transcription activator activity 1.89281746291341 bayes_pls_golite062009
sequence-specific DNA binding 1.87955444697212 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [177-829]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNGDFNHLPN FLLLKYDYNL QFLKNLLSVI IKDFFKRQNS LLLLLYPTNL WKNLLLDKIN  60
   61 STAMTGEPIT LLALLYIIQF TWSCFDDFKL FKVTKLIVSL TTNSKLDLKV LQLVNLSIFY 120
  121 FMGASVDSCK SKSSLTEHSN VNSVIWTNDL LNLNFTNILN MGLYINPKNL IPISGNNNNN 180
  181 KSNEEDDRIV TFWCFQFLSS WWSLIQGLPK SNFLTEEFQP KSISVLEIPR LKPFEILLNF 240
  241 IIYSLDGCNL LNISSLNVSD PNFQFFQNEL ESFKKNLLLW NLYHNLSDHD NFRFLTSSSN 300
  301 KKLTTNLLLK NLTGLNHKLN QPDFVEIQLT LFYLSLKLMT LKEGDQDLKK EDISLEILSL 360
  361 YFLILTDDSN NDDNQQLQPQ QLNLYHFTPF NSIDIIDLCL NNLNNWSLSL KYESGQNQPH 420
  421 SSKIKFEKFQ NFLNHWCPIW YYDEFSTNPF LQILKINFKL LPFETIHYSQ EEQRLLISLN 480
  481 KLRYLDAVSS FNSSSVKSNF ASKVNTQLNL LQHSSSNSNF LDASPYDFNK IFMNNFENYD 540
  541 YETDEGYAED DDEEDSDSDN SLPLEIPFKK SKNKCKNRNK ELSQRLSLFE NRDSNSVDFN 600
  601 TDTNLNLNPD SPSVTSSKKK YLDHIILDNR DIVSNHDSSK QKFKIQNILN STF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle