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View Structure Prediction Details

Protein: YKL222C
Organism: Saccharomyces cerevisiae
Length: 705 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL222C.

Description E-value Query
Range
Subject
Range
YKW2_YEAST - Uncharacterized transcriptional regulatory protein YKL222C OS=Saccharomyces cerevisiae (strain ATCC ...
YKL222C - Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ...
gi|190409625 - gi|190409625|gb|EDV12890.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
0.0 [1..705] [1..705]
gi|2262187 - gi|2262187|gb|AAB63563.1| FacB [Aspergillus niger]
5.0E-77 [1..480] [1..490]
gi|2262191 - gi|2262191|gb|AAB63565.1| acetate regulatory DNA binding protein FacB [Emericella nidulans]
gi|67516815, gi|... - gi|67516815|ref|XP_658293.1| hypothetical protein AN0689.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
7.0E-75 [1..480] [1..492]
ACU15_NEUCR - Transcriptional activator protein acu-15 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS ...
ACU15_NEUCR, AC1... - Transcriptional activator protein acu-15 OS=Neurospora crassa GN=acu-15 PE=1 SV=2, (P87000) Transcri...
9.0E-74 [1..480] [1..493]
gi|2262189 - gi|2262189|gb|AAB63564.1| FacB [Aspergillus oryzae]
5.0E-72 [1..480] [1..487]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-69 [5..563] [20..603]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNTELSQKK KLDRQSRRKP AKSCHFCRVR KLKCDRVRPF CGSCSSRNRK QCEYKENTSA  60
   61 MEDQLRKKYR RCSKLEMARR IEELESQLTK QSQPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.94696
Match: 1hwtD_
Description: Hap1 (Cyp1); HAP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
sequence-specific DNA binding 2.98081393153291 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
transcription activator activity 2.24483536326713 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [96-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHEGQNPLSN MRYLSSKHNR HILYGPTSYR AILATQTDTF AKYREEIWQV LKLSRNNWKR  60
   61 EHHYSTLSEI SSIETAPPHS GSPSVIEYLC ESLPNYEVLC EYLTDFFASD FYD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [209-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYQIVHKEKV LRDLQDCFVK GPRSHKTGQH TIISLNLDSK KNYYKVGVMT AIMCLASHPK  60
   61 EVPEAIEVFH KVLTSFVSAK VFYTERVQFL FLRYLYINVA GLDGGDQSHC IFIHGLTIDT 120
  121 AIHMGLNEDL RRLYLSKNHP IEEIPYLERL WLWILFTDVK ISLSTGIPVR INDDFVNKVR 180
  181 LENYSSSGDI LLYKTTLRLR NIMKQIHARE KPPDIPLIIE DLKKFTIKMF KPLDFYLNAS 240
  241 NLNG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [453-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEFTELQLWH ATLHMIGSLS NLYTLTHQDF DARIFNFSVL APLNSLHLCF NVLETYFELD  60
   61 NSKLSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [519-705]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSLCLSKKWP HLNNALFLIY VNAFRALIQI YTIFLQYMEN KDIQLFIQRN SSALTYSICP  60
   61 GDFEGPHNKC ISLKIAFKEM ENIFDHIHQE KLKPLTQIWQ NSYYFSIIIS MEKIGRRAFN 120
  121 KGMKNIDEGP ETENDATENS LTTILNDLEG PLEDFSENFI DDILGSPSAF FDTAISGWSN 180
  181 FEDFFSR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle