YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: SEC61
Organism: Saccharomyces cerevisiae
Length: 480 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC61.

Description E-value Query
Range		 Subject
Range
gi|6581004 - gi|6581004|gb|AAF18411.1|AF190652_1 putative integral membrane protein [Phaseolus vulgaris]
 0.0 [2..469] [3..470]
S61A2_ONCMY - Protein transport protein Sec61 subunit alpha isoform B OS=Oncorhynchus mykiss GN=sec61ab PE=2 SV=3
 0.0 [3..466] [2..465]
gi|13936273, gi|... - gi|24119237|ref|NP_705945.1| Sec61 alpha like 1 [Danio rerio], gi|13936273|gb|AAK40295.1| Sec61 alph...
 0.0 [4..466] [3..465]
S61A2_MOUSE - Protein transport protein Sec61 subunit alpha isoform 2 OS=Mus musculus GN=Sec61a2 PE=2 SV=3
gi|34876835 - gi|34876835|ref|XP_341559.1| PREDICTED: similar to Sec61, alpha subunit 2 [Rattus norvegicus]
S61A2_BOVIN - Protein transport protein Sec61 subunit alpha isoform 2 OS=Bos taurus GN=SEC61A2 PE=2 SV=3
SEC61A2 - Sec61 alpha 2 subunit (S. cerevisiae)
 0.0 [3..466] [2..465]
gi|19335712 - gi|19335712|gb|AAL85625.1| probable transport protein Sec61 alpha subunit [Aedes aegypti]
 0.0 [3..466] [2..465]
S61A1_MOUSE - Protein transport protein Sec61 subunit alpha isoform 1 OS=Mus musculus GN=Sec61a1 PE=1 SV=2
gi|206886 - gi|206886|gb|AAA42125.1| sec61-like protein [Rattus sp.]
ENSPTRT00000028666 - null
S61A1_PONPY - Protein transport protein Sec61 subunit alpha isoform 1 - Pongo pygmaeus (Orangutan)
gi|157170276, gi... - gi|162319052|gb|AAI56689.1| Sec61 alpha 1 subunit (S. cerevisiae) [synthetic construct], gi|15717027...
CCDS3046.1_1 - null
S61A1_PONAB - Protein transport protein Sec61 subunit alpha isoform 1 OS=Pongo abelii GN=SEC61A1 PE=2 SV=3
SEC61A1 - Sec61 alpha 1 subunit (S. cerevisiae)
ENSCJAT00000010395 - null
S61A1_RAT - Protein transport protein Sec61 subunit alpha isoform 1 OS=Rattus norvegicus GN=Sec61a1 PE=2 SV=2
 0.0 [4..466] [3..465]
S61A1_CANLF - Protein transport protein Sec61 subunit alpha isoform 1 OS=Canis lupus familiaris GN=SEC61A1 PE=1 SV...
 0.0 [4..466] [3..465]
CE14954 - protein transport protein SEC61 alpha subunit status:Confirmed UniProt:O18239 protein_id:CAB16516.1
 0.0 [3..467] [2..463]

Back

Predicted Domain #1
Region A:
Residues: [1-72] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNRVLDLF KPFESFLPEV IAPERKVPYN QKLIWTGVSL LIFLILGQIP LYGIVSSETS  60
   61 DPLYWLRAML AS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
ribonucleoprotein binding 5.96221631042313 bayes_pls_golite062009
protein transporter activity 5.55929343005534 bayes_pls_golite062009
transporter activity 3.32223562584466 bayes_pls_golite062009
substrate-specific transporter activity 3.22714325269757 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 2.12732472524264 bayes_pls_golite062009
macromolecule transmembrane transporter activity 2.12732472524264 bayes_pls_golite062009
protein transmembrane transporter activity 1.76187269823414 bayes_pls_golite062009
transmembrane transporter activity 1.67782980643723 bayes_pls_golite062009
binding 1.4562802789412 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.42890247609405 bayes_pls_golite062009
primary active transmembrane transporter activity 1.15847548838424 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.15316743403707 bayes_pls_golite062009
active transmembrane transporter activity 1.10003802565492 bayes_pls_golite062009
peptide transporter activity 1.01893828721893 bayes_pls_golite062009
protein binding 0.674651002700028 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [73-480] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRGTLLELGV SPIITSSMIF QFLQGTQLLQ IRPESKQDRE LFQIAQKVCA IILILGQALV  60
   61 VVMTGNYGAP SDLGLPICLL LIFQLMFASL IVMLLDELLS KGYGLGSGIS LFTATNIAEQ 120
  121 IFWRAFAPTT VNSGRGKEFE GAVIAFFHLL AVRKDKKRAL VEAFYRTNLP NMFQVLMTVA 180
  181 IFLFVLYLQG FRYELPIRST KVRGQIGIYP IKLFYTSNTP IMLQSALTSN IFLISQILFQ 240
  241 KYPTNPLIRL IGVWGIRPGT QGPQMALSGL AYYIQPLMSL SEALLDPIKT IVYITFVLGS 300
  301 CAVFSKTWIE ISGTSPRDIA KQFKDQGMVI NGKRETSIYR ELKKIIPTAA AFGGATIGAL 360
  361 SVGSDLLGTL GSGASILMAT TTIYGYYEAA AKEGGFTKNL VPGFSDLM

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 12.017729
Match: PF00344
Description: eubacterial secY protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle