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View Structure Prediction Details

Protein: AEP3
Organism: Saccharomyces cerevisiae
Length: 606 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AEP3.

Description E-value Query
Range
Subject
Range
PPR99_ARATH - Pentatricopeptide repeat-containing protein At1g63130, mitochondrial OS=Arabidopsis thaliana GN=At1g...
0.0 [33..601] [58..597]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [36..601] [63..599]
gi|32527604 - gi|32527604|gb|AAP86199.1| pentatricopeptide repeat-containing protein [Raphanus sativus]
0.0 [1..605] [62..648]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTLRCLTQA LSKSGREAPK LYQKVIFPGL FREGIPIANV KKVDEKIIDS PTSTSVNGEA  60
   61 KKIVRHGVKY EREQVKEYLS SLPTLTLSRK QIRDDYDEER AKRMYMFSKQ TNSSNKFQKL 120
  121 LTAKSQEFTR ELLTLLID

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [139-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CTSNEKNSGP ERFTRKFLKF SNDEIPPLPD FSKNPQLFEN YIGILSHTKF NFRSSSKLNG  60
   61 IVRKMLRHLL HPTNKTTLPL RSAQVYNDSI YFFSEHFDFA SCREIFAQMK AEGTKPNTIT 120
  121 FNLLLRNVVK NSHIRKTKHP DDEVLFYLRS MRNHGVFADV ITWTTCYNFL RDEVSRQLYI 180
  181 VQMGEHLGNF NVNFVYTVLR NGDYRAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [346-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCLKVLAANS LPISRKTFYL CIERLLNEEQ LETASKLLDY GFQHLKSNFK LDSEAMNHFM  60
   61 RVFANKGRSD LAFLCYNTCR KIYKIKPDSQ TFEMLFKALV RNGNTKNFGA VLQYIKDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1na0A_
Description: Designed protein cTPR3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.69757163267229 bayes_pls_golite062009
oxidoreductase activity 0.967526235944614 bayes_pls_golite062009
protein binding 0.931467806305272 bayes_pls_golite062009
RNA binding 0.675746721046834 bayes_pls_golite062009
transcription regulator activity 0.663212626739423 bayes_pls_golite062009
nucleic acid binding 0.54028771192401 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.465749123849318 bayes_pls_golite062009
hydrolase activity 0.443144569020145 bayes_pls_golite062009
DNA binding 0.36234393273743 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [464-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVSEGFGLRT SYWRTKADSI FKFGSPNTLS EKSIEKARKL LGNLIASEGE FSWKIWKESD  60
   61 SSQKKILRFL GCIPTTLRCT NTAQDHQKPT NLPSNISQKK REYRNRVKAI ATKAALEKRM 120
  121 AYIKDNDVAF KKELVKRRIV GEV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle