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View Structure Prediction Details

Protein: GPC4
Organism: Homo sapiens
Length: 556 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPC4.

Description E-value Query
Range
Subject
Range
gi|109132298 - gi|109132298|ref|XP_001097252.1| PREDICTED: similar to glypican 4 [Macaca mulatta]
842.0 [0..1] [556..1]
gi|3420277 - gi|3420277|gb|AAC31899.1| glypican 4 [Homo sapiens]
831.0 [0..1] [556..1]
gi|74008970 - gi|74008970|ref|XP_549265.2| PREDICTED: similar to glypican 4 [Canis familiaris]
825.0 [0..1] [556..1]
gi|55726366 - gi|55726366|emb|CAH89953.1| hypothetical protein [Pongo abelii]
GPC6_PONAB - Glypican-6 OS=Pongo abelii GN=GPC6 PE=2 SV=1
816.0 [0..21] [556..21]
GPC6_MOUSE - Glypican-6 OS=Mus musculus GN=Gpc6 PE=1 SV=1
811.0 [0..20] [556..20]
gi|62078949, gi|... - gi|62078949|ref|NP_001014130.1| glypican 4 [Rattus norvegicus], gi|51980590|gb|AAH81962.1| Glypican ...
805.0 [0..24] [556..24]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARFGLPALL CTLAVLSAAL LAAELKSKSC SEVRRLYVSK GFNKNDAPLH EINGDHLKIC  60
   61 PQGSTCCSQE MEEKYSLQSK DDFKSVVSEQ CNHLQAVFAS RYKKFD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [107-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFFKELLENA EKSLNDMFVK TYGHLYMQNS ELFKDLFVEL KRYYVVGNVN LEEMLNDFWA  60
   61 RLLERMFRLV NSQYHFTDEY LECVSKYTEQ LKPFGDVPRK LKLQVTRAFV AARTFAQGLA 120
  121 VAGDVVSKVS V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.977 N/A N/A a.118.22 Description not found.

Predicted Domain #3
Region A:
Residues: [238-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNPTAQCTHA LLKMIYCSHC RGLVTVKPCY NYCSNIMRGC LANQGDLDFE WNNFIDAMLM  60
   61 VAERLEGPF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.841 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains

Predicted Domain #4
Region A:
Residues: [307-431]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIESVMDPID VKISDAIMNM QDNSVQVSQK VFQGCGPPKP LPAGRISRSI SESAFSARFR  60
   61 PHHPEERPTT AAGTSLDRLV TDVKEKLKQA KKFWSSLPSN VCNDERMAAG NGNEDDCWNG 120
  121 KGKSR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [432-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLFAVTGNGL ANQGNNPEVQ VDTSKPDILI LRQIM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [467-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALRVMTSKMK NAYNGNDVDF FDISDESSGE GSGSGCEYQQ CPSEFDYNAT DHAGKSANEK  60
   61 ADSAGVRPGA QAYLLTVFCI LFLVMQREWR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle