YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1279761, gi\|7...
Organism:	Homo sapiens
Length:	341 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1279761, gi|7....

Description	E-value	Query Range	Subject Range
gi\|109075948 - gi\|109075948\|ref\|XP_001086103.1\| PREDICTED: similar to ADP-ribosylation factor interacting protein 1...	0.0	[1..341]	[142..477]
gi\|73977955 - gi\|73977955\|ref\|XP_867776.1\| PREDICTED: similar to ADP-ribosylation factor interacting protein 1 iso...	0.0	[1..341]	[1..341]
gi\|219841958, gi... - gi\|82890050\|ref\|XP_904285.1\| PREDICTED: ADP-ribosylation factor interacting protein 1 isoform 4 [Mus...	0.0	[1..341]	[1..341]
ENSPTRT00000030708 - null ARFIP1 - ADP-ribosylation factor interacting protein 1	0.0	[1..341]	[1..373]
ARFP1_RAT - Arfaptin-1 OS=Rattus norvegicus GN=Arfip1 PE=1 SV=1	0.0	[1..341]	[1..366]

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Predicted Domain #1

Region A:
Residues: [1-103]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQESPKNSA AEIPVTSNGE VDDSREHSFN RDLKHSLPSG LGLSETQITS HGFDNTKEGV  60
   61 IEAGAFQGGQ RTQTKSGPVI LADEIKNPAM EKLELVRKWS LNT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [104-341]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKCTRQIISE KLGRGSRTVD LELEAQIDIL RDNKKKYENI LKLAQTLSTQ LFQMVHTQRQ  60
   61 LGDAFADLSL KSLELHEEFG YNADTQKLLA KNGETLLGAI NFFIASVNTL VNKTIEDTLM 120
  121 TVKQYESARI EYDAYRTDLE ELNLGPRDAN TLPKIEQSQH LFQAHKEKYD KMRNDVSVKL 180
  181 KFLEENKVKV LHNQLVLFHN AIAAYFAGNQ KQLEQTLKQF HIKLKTPGVD APSWLEEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.0
Match:	1i49A
Description:	Arfaptin, Rac-binding fragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytoskeletal protein binding	3.124619761789	bayes_pls_golite062009
binding	2.43584893484993	bayes_pls_golite062009
protein binding	1.87308005875135	bayes_pls_golite062009
signal transducer activity	1.15315260510573	bayes_pls_golite062009
molecular transducer activity	1.15315260510573	bayes_pls_golite062009
GTPase binding	0.50066793947946	bayes_pls_golite062009
GTPase regulator activity	0.459881864914566	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	0.456472132383968	bayes_pls_golite062009
enzyme regulator activity	0.180886944097381	bayes_pls_golite062009
small GTPase binding	0.0531578648468707	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: