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View Structure Prediction Details

Protein: GPC6
Organism: Homo sapiens
Length: 555 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPC6.

Description E-value Query
Range
Subject
Range
gi|55726366 - gi|55726366|emb|CAH89953.1| hypothetical protein [Pongo abelii]
GPC6_PONAB - Glypican-6 OS=Pongo abelii GN=GPC6 PE=2 SV=1
879.0 [0..1] [555..1]
GPC6_MOUSE - Glypican-6 OS=Mus musculus GN=Gpc6 PE=1 SV=1
867.0 [0..1] [555..1]
gi|109502845 - gi|109502845|ref|XP_001074682.1| PREDICTED: similar to Glypican-6 precursor [Rattus norvegicus]
849.0 [0..1] [555..1]
gi|109132298 - gi|109132298|ref|XP_001097252.1| PREDICTED: similar to glypican 4 [Macaca mulatta]
802.0 [0..9] [555..9]
gi|123996633, gi... - gi|123996633|gb|ABM85918.1| glypican 4 [synthetic construct], gi|123981812|gb|ABM82735.1| glypican 4...
GPC4 - glypican 4
793.0 [0..9] [555..9]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSWIGAVIL PLLGLLLSLP AGADVKARSC GEVRQAYGAK GFSLADIPYQ EIAGEHLRIC  60
   61 PQEYTCCTTE MEDKLSQQSK LEFENLVEET SHFVRTTFVS RHKKFD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [107-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFFRELLENA EKSLNDMFVR TYGMLYMQNS EVFQDLFTEL KRYYTGGNVN LEEMLNDFWA  60
   61 RLLERMFQLI NPQYHFSEDY LECVSKYTDQ LKPFGDVPRK LKIQVTRAFI AARTFVQGLT 120
  121 VGREVANRVS K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.962 N/A N/A a.24.4 Hemerythrin

Predicted Domain #3
Region A:
Residues: [238-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSPTPGCIRA LMKMLYCPYC RGLPTVRPCN NYCLNVMKGC LANQADLDTE WNLFIDAMLL  60
   61 VAERLEGPF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.920 N/A N/A a.2.3 Chaperone J-domain

Predicted Domain #4
Region A:
Residues: [307-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIESVMDPID VKISEAIMNM QENSMQVSAK VFQGCGQPKP APALRSARSA PENFNTRFRP  60
   61 YNPEERPTTA A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [378-555]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTSLDRLVTD IKEKLKLSKK VWSALPYTIC KDESVTAGTS NEEECWNGHS KARYLPEIMN  60
   61 DGLTNQINNP EVDVDITRPD TFIRQQIMAL RVMTNKLKNA YNGNDVNFQD TSDESSGSGS 120
  121 GSGCMDDVCP TEFEFVTTEA PAVDPDRREV DSSAAQRGHS LLSWSLTCIV LALQRLCR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle