| Protein: | METTL3 |
| Organism: | Homo sapiens |
| Length: | 580 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for METTL3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..580] | [1..580] |
|
|
0.0 | [1..580] | [1..592] |
|
|
0.0 | [1..580] | [1..580] |
|
|
0.0 | [1..580] | [1..580] |
|
|
0.0 | [1..580] | [1..580] |
|
|
0.0 | [1..580] | [1..580] |
|
Region A: Residues: [1-141] |
1 11 21 31 41 51
| | | | | |
1 MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSGG 60
61 PKPSTASAVP ELATDPELEK KLLHHLSDLA LTLPTDAVSI CLAISTPDAP ATQDGVESLL 120
121 QKFAAQELIE VKRGLLQDDA H
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [142-231] |
1 11 21 31 41 51
| | | | | |
1 PTLVTYADHS KLSAMMGAVA EKKGPGEVAG TVTGQKRRAE QDSTTVAAFA SSLVSGLNSS 60
61 ASEPAKEPAK KSRKHAASDV DLEIESLLNQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [232-363] |
1 11 21 31 41 51
| | | | | |
1 QSTKEQQSKK VSQEILELLN TTTAKEQSIV EKFRSRGRAQ VQEFCDYGTK EECMKASDAD 60
61 RPCRKLHFRR IINKHTDESL GDCSFLNTCF HMDTCKYVHY EIDACMDSEA PGSKDHTPSQ 120
121 ELALTQSVGG DS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [364-580] |
1 11 21 31 41 51
| | | | | |
1 SADRLFPPQW ICCDIRYLDV SILGKFAVVM ADPPWDIHME LPYGTLTDDE MRRLNIPVLQ 60
61 DDGFLFLWVT GRAMELGREC LNLWGYERVD EIIWVKTNQL QRIIRTGRTG HWLNHGKEHC 120
121 LVGVKGNPQG FNQGLDCDVI VAEVRSTSHK PDEIYGMIER LSPGTRKIEL FGRPHNVQPN 180
181 WITLGNQLDG IHLLDPDVVA RFKQRYPDGI ISKPKNL
|
| Detection Method: | |
| Confidence: | 1.04 |
| Match: | 1g60A |
| Description: | Methyltransferase mboII |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| methyltransferase activity | 3.68431317301075 | bayes_pls_golite062009 |
| N-methyltransferase activity | 3.64494850793256 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 3.60853685152199 | bayes_pls_golite062009 |
| protein methyltransferase activity | 3.51986359093355 | bayes_pls_golite062009 |
| DNA-methyltransferase activity | 3.47923436720314 | bayes_pls_golite062009 |
| S-adenosylmethionine-dependent methyltransferase activity | 2.91374296950366 | bayes_pls_golite062009 |
| histone methyltransferase activity | 2.666651371662 | bayes_pls_golite062009 |
| RNA methyltransferase activity | 2.63941856307703 | bayes_pls_golite062009 |
| protein-arginine N-methyltransferase activity | 1.99340565364513 | bayes_pls_golite062009 |
| arginine N-methyltransferase activity | 1.99340565364513 | bayes_pls_golite062009 |
| transferase activity | 1.97261773840408 | bayes_pls_golite062009 |
| rRNA methyltransferase activity | 1.85380504590369 | bayes_pls_golite062009 |
| binding | 1.65046086869658 | bayes_pls_golite062009 |
| histone-arginine N-methyltransferase activity | 1.64765900536818 | bayes_pls_golite062009 |
| transcription regulator activity | 1.59599828300594 | bayes_pls_golite062009 |
| site-specific DNA-methyltransferase (adenine-specific) activity | 1.5743030926483 | bayes_pls_golite062009 |
| DNA binding | 1.48691268044769 | bayes_pls_golite062009 |
| tRNA methyltransferase activity | 1.38914410921124 | bayes_pls_golite062009 |
| nucleic acid binding | 1.36595590938226 | bayes_pls_golite062009 |
| protein-arginine omega-N monomethyltransferase activity | 1.27753381141602 | bayes_pls_golite062009 |
| DNA (cytosine-5-)-methyltransferase activity | 1.23915163423518 | bayes_pls_golite062009 |
| catalytic activity | 1.16970557486814 | bayes_pls_golite062009 |
| RNA binding | 1.10288658549985 | bayes_pls_golite062009 |
| protein-arginine omega-N symmetric methyltransferase activity | 0.862671287243863 | bayes_pls_golite062009 |
| rRNA (uridine) methyltransferase activity | 0.837734735695963 | bayes_pls_golite062009 |
| histone methyltransferase activity (H4-R3 specific) | 0.735680462496249 | bayes_pls_golite062009 |
| protein-arginine omega-N asymmetric methyltransferase activity | 0.51222176401398 | bayes_pls_golite062009 |
| tRNA (cytosine)-methyltransferase activity | 0.325961687103877 | bayes_pls_golite062009 |
| tRNA (cytosine-5-)-methyltransferase activity | 0.325961687103877 | bayes_pls_golite062009 |
| histone binding | 0.230289474831554 | bayes_pls_golite062009 |
| rRNA (adenine) methyltransferase activity | 0.113328595762489 | bayes_pls_golite062009 |
| rRNA (adenine-N6,N6-)-dimethyltransferase activity | 0.0390774859535424 | bayes_pls_golite062009 |
| mRNA methyltransferase activity | 0.03091406523028 | bayes_pls_golite062009 |
| mRNA (guanine-N7-)-methyltransferase activity | 0.03091406523028 | bayes_pls_golite062009 |
