| Protein: | RFX3 |
| Organism: | Homo sapiens |
| Length: | 749 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFX3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..749] | [1..749] |
|
|
0.0 | [1..749] | [1..749] |
|
|
0.0 | [1..749] | [1..749] |
|
|
0.0 | [1..749] | [1..749] |
|
|
0.0 | [1..749] | [1..749] |
|
Region A: Residues: [1-168] |
1 11 21 31 41 51
| | | | | |
1 MQTSETGSDT GSTVTLQTSV ASQAAVPTQV VQQVPVQQQV QQVQTVQQVQ HVYPAQVQYV 60
61 EGSDTVYTNG AIRTTTYPYT ETQMYSQNTG GNYFDTQGSS AQVTTVVSSH SMVGTGGIQM 120
121 GVTGGQLISS SGGTYLIGNS MENSGHSVTH TTRASPATIE MAIETLQK
|
| Detection Method: |  |
| Confidence: | 3.522879 |
| Match: | 1m2vB |
| Description: | Sec24 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [169-258] |
1 11 21 31 41 51
| | | | | |
1 SDGLSTHRSS LLNSHLQWLL DNYETAEGVS LPRSTLYNHY LRHCQEHKLD PVNAASFGKL 60
61 IRSIFMGLRT RRLGTRGNSK YHYYGIRVKP
|
| Detection Method: | |
| Confidence: | 33.221849 |
| Match: | 1dp7P |
| Description: | Class II MHC transcription factor RFX1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.55329976718261 | bayes_pls_golite062009 |
| DNA binding | 5.08959163553491 | bayes_pls_golite062009 |
| nucleic acid binding | 4.69183445184264 | bayes_pls_golite062009 |
| transcription factor activity | 4.33152142980289 | bayes_pls_golite062009 |
| transcription repressor activity | 3.85678231380989 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.48053910222825 | bayes_pls_golite062009 |
| transcription activator activity | 2.37668609508629 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.70025468248325 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.96257232341735 | bayes_pls_golite062009 |
| transcription factor binding | 0.85714789329232 | bayes_pls_golite062009 |
| protein binding | 0.753698599635855 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.322180400748724 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.0856082199488197 | bayes_pls_golite062009 |
|
Region A: Residues: [259-322] |
1 11 21 31 41 51
| | | | | |
1 DSPLNRLQED MQYMAMRQQP MQQKQRYKPM QKVDGVADGF TGSGQQTGTS VEQTVIAQSQ 60
61 HHQQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [323-514] |
1 11 21 31 41 51
| | | | | |
1 FLDASRALPE FGEVEISSLP DGTTFEDIKS LQSLYREHCE AILDVVVNLQ FSLIEKLWQT 60
61 FWRYSPSTPT DGTTITESSN LSEIESRLPK AKLITLCKHE SILKWMCNCD HGMYQALVEI 120
121 LIPDVLRPIP SALTQAIRNF AKSLEGWLSN AMNNIPQRMI QTKVAAVSAF AQTLRRYTSL 180
181 NHLAQAARAV LQ
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [515-749] |
1 11 21 31 41 51
| | | | | |
1 NTSQINQMLS DLNRVDFANV QEQASWVCQC DDNMVQRLET DFKMTLQQQS TLEQWAAWLD 60
61 NVMMQALKPY EGRPSFPKAA RQFLLKWSFY SSMVIRDLTL RSAASFGSFH LIRLLYDEYM 120
121 FYLVEHRVAQ ATGETPIAVM GEFGDLNAVS PGNLDKDEGS EVESEMDEEL DDSSEPQAKR 180
181 EKTELSQAFP VGCMQPVLET GVQPSLLNPI HSEHIVTSTQ TIRQCSATGN TYTAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
