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View Structure Prediction Details

Protein: gi|116008110, gi...
Organism: Drosophila melanogaster
Length: 1704 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|116008110, gi....

Description E-value Query
Range
Subject
Range
gi|62473051, gi|... - gi|62473051|ref|NP_001014681.1| Darkener of apricot CG33553-PD, isoform D [Drosophila melanogaster],...
1670.0 [0..1] [1666..1]

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Predicted Domain #1
Region A:
Residues: [1-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNELSELIA LGCPDLAAQK PQGGSTQVEL ILNTERRLSI KQMTATDLAT LRAAAAAEAE  60
   61 ARSRAQAEAE ALAIAQEQFR QAREAESKAR ARAALEVQAQ LQRVMESEKR RQQEEEERRI 120
  121 RQQAEEEQED DEDDDNDEEE ELTKGSLPTN SGPRERIASL PCNIDDAMEM HLLNVSQPKA 180
  181 SSKDDSPPKK STSHIADSIE LLRMQRAARD ARSHNRSRER SISPDRNRER SAAPDRLQSS 240
  241 ASMSSLDSAS ASASRQPSKA GSRRGSTTSA TGVEPPLMAA PPQPTKFPLT KTVSAPNMDR 300
  301 RRSSLTSLFP GPSPLVAPEP SLHTNP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.09691
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [327-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPRVQEQIEE DRRRRRMDDG YREIPSGKMV HRTKTPPPVG TNLGVSLKRV TAPSGSITIK  60
   61 PKESPMLGVV LRRVEKKTVP QKSILDDDKP LYHFSIVRSD HKEHVPAQKP KPKPAPPAAK 120
  121 PSPGGILTGP QVIRNAPKQP VPV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #3
Region A:
Residues: [470-604]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPQRPMPGVP ITITKIEGDK IIIIKKIIVP KNSKIPEQYL QMSEDAGKPA NTVPSAVSSS  60
   61 AAPSPSLRTK EESQPAMQKP TPPPASGQQF FQVVSPQFAS VLSSSIPESK CAVRSPISSP 120
  121 LAIRKSRPPL LPSSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1uffA
Description: Solution structure of the first SH3 domain of human intersectin2 (KIAA1256)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.375837873453985 bayes_pls_golite062009
protein binding 0.25580402341401 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [605-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTPPLPRKH HPLAYNAATG TISSASGAAL PSRLMATIAS SPASSISLSS CSSPSSSPPP  60
   61 PVPCRAPKNA SRPVAVTAAP PPSTSNEISL DKLLQQQQEL EEKSAAATNS AKMDAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [721-781]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYDAEIEMMN KYLKSLPDYS ELDRKLHQEF QECEDLYDKI KRQQQPLAKS NSQQSVTKAV  60
   61 G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [782-837]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGVPAISSGL SKSSSINFAQ NPSSRGAAPR LAYPSIFSQA AGEPKLQRSI SSSNMP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [838-1059]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISAPNSMRPL PTKNGLQSGS NLSLNKQLMN EFWSENLTSS QKRQTPKRTF WNYEKICGAQ  60
   61 LGDAGQPFKV DAKTAKKLAI FDPTVAEAAQ KELQRPQQSQ VPQNQPHKLQ KNASLSHLDL 120
  121 KVRQAVTKDD LYKLICNEQS PLAGSNFVSR VPVKQQFPAQ QQQVLPKSMS MTHVPGGGQP 180
  181 MGAPLLRTSS RTHIPSYMKN LPSLSRSTSN SAILMTQPRK EP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1060-1290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPKEPLKAPA PLPAIAAPTV GKPSGVLKSS SSSCVPSPRC AAAFFRRPQE ANNPQQQHHQ  60
   61 PLQKPQQVAP IEESGPGDSA SLERKSEKSN STLSTSSFTV TNCCTTHLPQ LSKFTSSFHI 120
  121 APTTATTTAA TATPTPTGAA TTSDQQQQSG GTPAMVAANL EVPTSSSSSA ATKRQKDVDN 180
  181 KLEKCLNDML KLKTSSNNNS TSNSNNNAIM SHSLTGEHKD PKTALEGPTS S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1291-1479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSSKYIG ESQIPVPVQL YDPQKPLLQQ QQQQQRICYP IGKSNSTSQL PMGGYQRLLQ  60
   61 HQQQQHHQQQ QQQHQEQQQY PQHKRPFLNW NSFACSAMNG ASDPFMQQQH MPAHQQQQHL 120
  121 PHKLQQSYSS SHVPKQAPKS GLAMFLQKNT NKENKFGQPM QQQPPGMMPQ MYGYQAPQQQ 180
  181 SKIGYPRTG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1480-1556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APLTHSASFS SAQRPTALQF HQQHQQQQHL QQQQQHPQQQ QHQHSSFGVG MMSRNYYNMP  60
   61 KQPERKPLQT FDPYAYP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1557-1614]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPNQMQPVKY QQQQQHPHTQ FQNASAGGGG GGAAGLQYDP NTNTQLFYAS PASSSSNK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1615-1704]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPQQPQQQQQ QQQSQLQQSN SVIFNHSGQQ HQPHQQQQNE MSKSALGLHF IEVDSIPPIY  60
   61 FCLVFVLHMC LNQKCPLTTR CRFQRKFAPK 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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