YRC Public Data Repository - Protein Structure Prediction

Protein:	COX11_MOUSE
Organism:	Mus musculus
Length:	275 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX11_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|109488791, gi... - ref\|XP_213433.2\| similar to COX11 homolog; cytochrome c oxidase subunit 11; cytochrome c oxidase ass...	490.0	[0..1]	[275..1]
gi\|60826960 - gi\|60826960\|gb\|AAX36778.1\| COX11-like cytochrome c oxidase assembly protein [synthetic construct]	472.0	[0..1]	[275..1]
COX11 - COX11 cytochrome c oxidase assembly homolog (yeast) gi\|60814946 - gi\|60814946\|gb\|AAX36326.1\| COX11-like cytochrome c oxidase assembly protein [synthetic construct]	471.0	[0..1]	[275..1]
gi\|55730891 - gi\|55730891\|emb\|CAH92164.1\| hypothetical protein [Pongo abelii] gi\|55730891\|emb\|... - hypothetical protein [Pongo pygmaeus]	456.0	[0..1]	[275..1]
gi\|109114390 - gi\|109114390\|ref\|XP_001102862.1\| PREDICTED: similar to COX11 homolog [Macaca mulatta]	455.0	[0..1]	[275..1]
gi\|73966488 - gi\|73966488\|ref\|XP_866470.1\| PREDICTED: similar to COX11 homolog isoform 2 [Canis familiaris]	426.0	[0..1]	[275..1]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGLWCPGWR LVASCGRGWR QPGWSGRTVV NAELVLRPGW DGLGGAERGL RRLGTWKRPC  60
   61 GVRGPATQPP RRPRSSNPFQ RAQEDEW

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [88-275]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRRNKTVLTY VAAAAVGMLG ASYAAVPLYR LYCQTTGLGG SAVAGHSSDQ IENMVPVKDR  60
   61 VIKVTFNADV HASLQWNFRP QQTEIYVVPG ETALAFYKAK NPTDKPVIGI STYNVVPFEA 120
  121 GQYFNKIQCF CFEEQRLNPQ EEVDMPVFFY IDPEFAEDPR MVNVDLITLS YTFFEAKEGH 180
  181 KLPVPGYN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.39794
Match:	1so9A
Description:	Solution Structure of apoCox11, 30 structures
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.26238051646126	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: