YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|114650545
Organism:	Pan troglodytes
Length:	252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114650545.

Description	E-value	Query Range	Subject Range
gi\|46575936, gi\|... - gi\|76825284\|gb\|AAI07005.1\| Fibroblast growth factor 14 [Mus musculus], gi\|46575936\|ref\|NP_997550.1\| ... gi\|3299786, gi\|1... - gi\|3299786\|dbj\|BAA31544.1\| fibroblast growth factor 14b [Rattus norvegicus], gi\|149050272\|gb\|EDM0259...	1.0E-91	[1..252]	[1..252]
gi\|45382137, gi\|... - gi\|6911123\|gb\|AAF31393.1\|AF199606_1 fibroblast growth factor homologous factor 4 isoform 1B [Gallus ...	6.0E-87	[1..252]	[1..253]
gi\|19070525 - gi\|19070525\|gb\|AAL83904.1\|AF348523_1 fibroblast growth factor-like factor-4D [Rattus norvegicus]	4.0E-67	[53..252]	[12..211]
gi\|28191242 - gi\|28191242\|gb\|AAO33291.1\| fibroblast growth factor-like protein [Meleagris gallopavo]	9.0E-65	[45..252]	[27..236]
gi\|109132469 - gi\|109132469\|ref\|XP_001084216.1\| PREDICTED: fibroblast growth factor 13 isoform 2 [Macaca mulatta] gi\|221045728, gi... - gi\|221045728\|dbj\|BAH14541.1\| unnamed protein product [Homo sapiens], gi\|221041872\|dbj\|BAH12613.1\| un...	2.0E-64	[45..252]	[46..255]
gi\|148230685, gi... - gi\|49899696\|gb\|AAH76721.1\| Fgf13-prov protein [Xenopus laevis], gi\|148230685\|ref\|NP_001086499.1\| fib...	7.0E-64	[45..252]	[46..255]
gi\|114650543 - gi\|114650543\|ref\|XP_001150157.1\| PREDICTED: fibroblast growth factor 14 isoform 1 [Pan troglodytes] gi\|109121204 - gi\|109121204\|ref\|XP_001093573.1\| PREDICTED: fibroblast growth factor 14 isoform 2 [Macaca mulatta] FGF14 - fibroblast growth factor 14	2.0E-63	[63..252]	[58..247]
gi\|73989458 - gi\|73989458\|ref\|XP_542656.2\| PREDICTED: similar to fibroblast growth factor 14 [Canis familiaris]	2.0E-63	[63..252]	[58..247]

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Predicted Domain #1

Region A:
Residues: [1-64]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKPVPLFRR TDFKLLLCNH KDLFFLRVSK LLDCFSPKSM WFLWNIFSKG THMLQCLCGK  60
   61 SLKK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [65-252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKNPTDPQLK GIVTRLYCRQ GYYLQMHPDG ALDGTKDDST NSTLFNLIPV GLRVVAIQGV  60
   61 KTGLYIAMNG EGYLYPSELF TPECKFKESV FENYYVIYSS MLYRQQESGR AWFLGLNKEG 120
  121 QAMKGNRVKK TKPAAHFLPK PLEVAMYREP SLHDVGETVP KPGVTPSKST SASAIMNGGK 180
  181 PVNKSKTT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.522879
Match:	1q1uA
Description:	Crystal structure of human FHF1b (FGF12b)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.90110516688922	bayes_pls_golite062009
receptor binding	2.16557070623757	bayes_pls_golite062009
protein binding	1.94397222237906	bayes_pls_golite062009
growth factor activity	1.45668559810417	bayes_pls_golite062009
cytokine activity	0.491912278395019	bayes_pls_golite062009
fibroblast growth factor receptor binding	0.379391310291065	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: