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View Structure Prediction Details

Protein: lectin-21Cb-PA
Organism: Drosophila melanogaster
Length: 257 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lectin-21Cb-PA.

Description E-value Query
Range
Subject
Range
gi|7159330, gi|6... - gi|7159330|gb|AAF37722.1|AF237686_1 MHC class I recognition receptor Ly49I [Mus musculus], gi|675446...
178.0 [0..3] [256..8]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHAPIPYDE RFIRRFPDYR LIDYPQGAQE NNCPKVSLSE RLEKRGEFSL VEFDPLLKFI  60
   61 VKNPHKEL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGEIEGLVGH TENKLQPMKS VIPNQSKALL NYLDLHSKLE YLDAALQKAI NSLQCSLKNT  60
   61 KVMSTGKPHP EFQKLGSRYF YIERHVRQNW FDAADKCRRM GGHLATPQDE DELYLIRKQL 120
  121 EARWFWLDIS NLVDKDQYIS LATGKEVSYL KWRHGEPKKS STANCAYLYA GDYYTYQCSD 180
  181 RNFFICQAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.522879
Match: 1sl6A
Description: Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13629480035749 bayes_pls_golite062009
carbohydrate binding 0.44675717945952 bayes_pls_golite062009
protein binding 0.059857076934361 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle