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View Structure Prediction Details

Protein: Lsm11-PA
Organism: Drosophila melanogaster
Length: 256 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Lsm11-PA.

Description E-value Query
Range
Subject
Range
gi|21430742 - gi|21430742|gb|AAM51049.1| SD11312p [Drosophila melanogaster]
450.0 [0..1] [256..1]
gi|54636551, gi|... - gi|54636551|gb|EAL25954.1| GA11912-PA [Drosophila pseudoobscura], gi|125810148|ref|XP_001361376.1| G...
297.0 [0..19] [253..1]
AGAP007326-PB - |protein_coding|2L:45423199:45424051:-1|gene:AGAP007326
gi|116132258, gi... - gi|118778178|ref|XP_308499.3| AGAP007326-PB [Anopheles gambiae str. PEST], gi|116132258|gb|EAA04750....
296.0 [0..18] [254..17]
LSM11 - LSM11, U7 small nuclear RNA associated
247.0 [0..1] [190..1]
gi|114603137 - gi|114603137|ref|XP_001138531.1| PREDICTED: hypothetical protein [Pan troglodytes]
247.0 [0..1] [190..1]
gi|109490584, gi... - gi|109490584|ref|XP_001068848.1| PREDICTED: similar to U7 snRNA-associated Sm-like protein Lsm11 [Ra...
238.0 [0..1] [190..70]
gi|109079550 - gi|109079550|ref|XP_001105388.1| PREDICTED: similar to cytochrome P450, family 20, subfamily A, poly...
231.0 [0..1] [193..1]
LSM11_MOUSE - U7 snRNA-associated Sm-like protein LSm11 OS=Mus musculus GN=Lsm11 PE=1 SV=1
228.0 [0..1] [190..1]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESRDRKTSN EDDSSEISEL DVGSDRFNPL RALYEPNFRV TDAVPKVIYQ NLAAFESALK  60
   61 KFGIWQLNKR QKPGSAEGGD QGTSKKASTS EAVDILPPER RFEPHQMPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [110-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSRKKHHRN IFTYMEAAVG PLELLTKCIS PASHNESNER RRVRVVIRKH GSVGGSVEGE  60
   61 LLAFDKQWNL LLRNVTETWK RRKYNYGEQN ICDTPVDCTG RLKELGITLP RTVVKNLNRK 120
  121 NVEIRRELPQ ILIRGENVVL VSLIPTK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.36
Match: 1b34B
Description: D2 core SNRNP protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
9.01879034070151 bayes_pls_golite062009
RNA binding 5.49978007278445 bayes_pls_golite062009
nucleic acid binding 3.63659317062066 bayes_pls_golite062009
binding 2.57641778478211 bayes_pls_golite062009
mRNA binding 2.42306415646781 bayes_pls_golite062009
protein binding 0.424600155973421 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle