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View Structure Prediction Details

Protein: Lsm11-PA
Organism: Drosophila melanogaster
Length: 256 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Lsm11-PA.

Description E-value Query
Range
Subject
Range
gi|21430742 - gi|21430742|gb|AAM51049.1| SD11312p [Drosophila melanogaster]
450.0 [0..1] [256..1]
gi|54636551, gi|... - gi|54636551|gb|EAL25954.1| GA11912-PA [Drosophila pseudoobscura], gi|125810148|ref|XP_001361376.1| G...
297.0 [0..19] [253..1]
AGAP007326-PB - |protein_coding|2L:45423199:45424051:-1|gene:AGAP007326
gi|116132258, gi... - gi|118778178|ref|XP_308499.3| AGAP007326-PB [Anopheles gambiae str. PEST], gi|116132258|gb|EAA04750....
296.0 [0..18] [254..17]
LSM11 - LSM11, U7 small nuclear RNA associated
247.0 [0..1] [190..1]
gi|114603137 - gi|114603137|ref|XP_001138531.1| PREDICTED: hypothetical protein [Pan troglodytes]
247.0 [0..1] [190..1]
gi|109490584, gi... - gi|109490584|ref|XP_001068848.1| PREDICTED: similar to U7 snRNA-associated Sm-like protein Lsm11 [Ra...
238.0 [0..1] [190..70]
gi|109079550 - gi|109079550|ref|XP_001105388.1| PREDICTED: similar to cytochrome P450, family 20, subfamily A, poly...
231.0 [0..1] [193..1]
LSM11_MOUSE - U7 snRNA-associated Sm-like protein LSm11 OS=Mus musculus GN=Lsm11 PE=1 SV=1
228.0 [0..1] [190..1]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESRDRKTSN EDDSSEISEL DVGSDRFNPL RALYEPNFRV TDAVPKVIYQ NLAAFESALK  60
   61 KFGIWQLNKR QKPGSAEGGD QGTSKKASTS EAVDILPPER RFEPHQMPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [110-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSRKKHHRN IFTYMEAAVG PLELLTKCIS PASHNESNER RRVRVVIRKH GSVGGSVEGE  60
   61 LLAFDKQWNL LLRNVTETWK RRKYNYGEQN ICDTPVDCTG RLKELGITLP RTVVKNLNRK 120
  121 NVEIRRELPQ ILIRGENVVL VSLIPTK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.36
Match: 1b34B
Description: D2 core SNRNP protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
9.01879034070151 bayes_pls_golite062009
RNA binding 5.49978007278445 bayes_pls_golite062009
nucleic acid binding 3.63659317062066 bayes_pls_golite062009
binding 2.57641778478211 bayes_pls_golite062009
mRNA binding 2.42306415646781 bayes_pls_golite062009
protein binding 0.424600155973421 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle