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View Structure Prediction Details

Protein: MCPH1-PA
Organism: Drosophila melanogaster
Length: 779 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCPH1-PA.

Description E-value Query
Range
Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
326.0 [0..2] [778..761]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTNEPSITN KLRSLLLDDQ AARDRLMLKP ALAVSKAISQ HRSEFHQDEN EAGAEGSAAK  60
   61 PDPPIGAATP TRQEGHWARL QQDLNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [87-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNAALRLRAI RALKSPTKSA YNTFDVPLAE QSIITMEERN PQEPPSLPEL LKDIVVYVEV  60
   61 RTGNDNRSEG VKSIIAKMGA QVKDRLTRTT THVVFKDGLL STYKKATEWN IPVVSILWIE 120
  121 ACKVQLKICD PKQFPISNIR MYEYPELFGK MPRVKFMQPD SELNQRPRKR QGT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.46
Match: 2d8mA
Description: No description for 2d8mA was found.

Predicted Domain #3
Region A:
Residues: [260-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTSSKDNEPG STNKRAQTGT PTTTTPKNDI SRFFRAINHN KPSDDEAIES PATKLLNRIS  60
   61 SGCYTPLPAG GTPQLMGTNG SGDAVAQKVQ AQKSLQFGEQ TDSNTPQAKP SSTSRPRRST 120
  121 VDPPPVMTPP VRTTRRRSCV AEISSPAATD TRMTRRRSSL LTSTVIHEAD PTQTAVAEPR 180
  181 MTRRRSSLLG IAKQAEETAQ RQTIQPITEE LAPVEENRNS IIMAETNIIN NTNCLEQSIE 240
  241 ITAVEAEASF KA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [512-628]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRRGTLYASE LMDISSPRRR SVAKSSLELR QENLAPRARQ SLSNVTTQTS FLDVEQQVTP  60
   61 LFSSTRLPTG QTTGNRRRTI FNMDMDVINE SIERMNQSHR MSLALANKAE LGESCQV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [629-779]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HEQEPPQAEP VPSQEPKRRR LFNPNDEVVI SPAMSNRKSR LSITGSGSSS SVQKRRRSLA  60
   61 TPAKSSSSEL CATTPLSKAV TNKEAEKSKS NTEISEASLD AVPEVKKSTS NAGEENEKPK 120
  121 GKSRTRIRTL VHTNMHQEQI NVIRKVGNTT E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle