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View Structure Prediction Details

Protein: MCPH1-PB
Organism: Drosophila melanogaster
Length: 826 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCPH1-PB.

Description E-value Query
Range
Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
327.0 [0..7] [823..771]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKFLLRNPT WKTKTYGSVV ASSAAAAKKT AASSTRRPLH DSNLGDFRSK AAAPSPKSLS  60
   61 QAPADDQAAR DRLMLKPALA VSKAISQHRS EFHQDENEAG AEGSAAKPDP P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGAATPTRQE GHWARLQQDL NSPNAALRLR AIRALKSPTK SAYNTFDVPL AEQSIITMEE  60
   61 RNPQEPPSLP ELLKDIVVYV EVRTGNDNRS EGVKSIIAKM GAQVKDRLTR TTTHVVFKDG 120
  121 LLSTYKKATE WNIPVVSILW IEACKVQLKI CDPKQFPISN IRMYEYPELF GKMPRVKFMQ 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.99
Match: 2d8mA
Description: No description for 2d8mA was found.

Predicted Domain #3
Region A:
Residues: [292-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDSELNQRPR KRQGTPTSSK DNEPGSTNKR AQTGTPTTTT PKNDISRFFR AINHNKPSDD  60
   61 EAIESPATKL LNRISSGCYT PLPAGGTPQL MGTNGSGDAV AQKVQAQKSL QFGEQTDSNT 120
  121 PQAKPSSTSR PRRSTVDPPP VMTPPVRTTR RRSCVAEISS PAATDTRMTR RRSSLLTSTV 180
  181 IHEADPTQTA VAEPRMTRRR SSLLGIAKQA EETAQRQTIQ PITEEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [518-697]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVEENRNSI IMAETNIINN TNCLEQSIEI TAVEAEASFK ADRRGTLYAS ELMDISSPRR  60
   61 RSVAKSSLEL RQENLAPRAR QSLSNVTTQT SFLDVEQQVT PLFSSTRLPT GQTTGNRRRT 120
  121 IFNMDMDVIN ESIERMNQSH RMSLALANKA ELGESCQVHE QEPPQAEPVP SQEPKRRRLF 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [698-826]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNDEVVISP AMSNRKSRLS ITGSGSSSSV QKRRRSLATP AKSSSSELCA TTPLSKAVTN  60
   61 KEAEKSKSNT EISEASLDAV PEVKKSTSNA GEENEKPKGK SRTRIRTLVH TNMHQEQINV 120
  121 IRKVGNTTE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle