| Protein: | Klp54D-PA |
| Organism: | Drosophila melanogaster |
| Length: | 844 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Klp54D-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
335.0 | [0..35] | [844..1] |
|
Region A: Residues: [1-148] |
1 11 21 31 41 51
| | | | | |
1 MGIWLVPCPR DILVLSKQST PYPAFAHSVA STQVTMVRRA SSVPHLNSSG GSSADSAGTS 60
61 GSRRGRAPVA GSRGRKTPST TSTGQSQRQS SGSSSSMPRS RSLTNGMRRL SPQKGTGSSG 120
121 GTGGGGGSSR NTPYFLRSRE NEIGSADT
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [149-421] |
1 11 21 31 41 51
| | | | | |
1 LEIVASKSTG SEECSTPEDN INVVVRVRPL NDKEKRDRHG STLQFPGNGQ VILEGNDVGQ 60
61 KRSHNRDSVR VFTYNVVFEP GATQEDILDY SGIKRIIEMG IEGFSCTAFC YGQTGSGKTH 120
121 TLTGPPDLFV GKPNPKDPRH GLIFRSFLYL FQLIKNRKDV NYVLKASFME IYNERVIDLL 180
181 NPGSARKPLA VRWSKKSGGF FVENLFTVDC EELDDLLAVL EEGMRNRAVG SHAMNDHSSR 240
241 SHTILTVHIL SDQQTDGGVF LSKHGKINFV DLA
|
| Detection Method: | |
| Confidence: | 80.522879 |
| Match: | 1x88A |
| Description: | Human Eg5 motor domain bound to Mg-ADP and monastrol |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| microtubule motor activity | 7.68336791348661 | bayes_pls_golite062009 |
| plus-end-directed microtubule motor activity | 4.97507344344589 | bayes_pls_golite062009 |
| GTPase activity | 4.92902654551215 | bayes_pls_golite062009 |
| microfilament motor activity | 4.176620576177 | bayes_pls_golite062009 |
| motor activity | 4.04927796049806 | bayes_pls_golite062009 |
| transporter activity | 3.10463051760206 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.95886887664984 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.95079405147356 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.87427509025394 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.85499564954033 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.85178667290149 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 2.77140616759165 | bayes_pls_golite062009 |
| microtubule plus-end binding | 2.71138928021716 | bayes_pls_golite062009 |
| tubulin binding | 2.67743463093593 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 2.61775212528604 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 2.61467977505707 | bayes_pls_golite062009 |
| microtubule binding | 2.59155206524122 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 2.57552435627908 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 2.57107347424517 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 2.57054427875021 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 2.50494515048649 | bayes_pls_golite062009 |
| ATPase activity, coupled | 2.43862163407966 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.4101693596493 | bayes_pls_golite062009 |
| ATPase activity | 2.39535714892224 | bayes_pls_golite062009 |
| actin binding | 2.2973522188675 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 2.07967285635739 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.91091452720653 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.63949223587737 | bayes_pls_golite062009 |
| hydrolase activity | 1.57549510726226 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.56325751172863 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.40384549325664 | bayes_pls_golite062009 |
| helicase activity | 1.33212695797068 | bayes_pls_golite062009 |
| actin filament binding | 1.28204719195916 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| G-protein-coupled receptor binding | 1.07726090199322 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.07479235523606 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.977237423302079 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.929901285538132 | bayes_pls_golite062009 |
| nucleotide binding | 0.922442819194247 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.920987930180051 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.920926158369519 | bayes_pls_golite062009 |
| nucleic acid binding | 0.777787753097919 | bayes_pls_golite062009 |
| molecular transducer activity | 0.683309012097319 | bayes_pls_golite062009 |
| signal transducer activity | 0.683309012097319 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.661834961742057 | bayes_pls_golite062009 |
| receptor activity | 0.633514002718998 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.557919489256916 | bayes_pls_golite062009 |
| kinetochore binding | 0.505370954958131 | bayes_pls_golite062009 |
| DNA binding | 0.479412476059825 | bayes_pls_golite062009 |
| ATP binding | 0.41092997612902 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.385813421701492 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.377870145186619 | bayes_pls_golite062009 |
| RNA helicase activity | 0.34746349346164 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 0.328186246219424 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 0.328186246219424 | bayes_pls_golite062009 |
| transcription regulator activity | 0.312171320541728 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.30832907234141 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.29532978396745 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.25143870859482 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.25143870859482 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.213018989352421 | bayes_pls_golite062009 |
| protein transporter activity | 0.178442534411253 | bayes_pls_golite062009 |
| metabotropic serotonin receptor binding | 0.178039386254807 | bayes_pls_golite062009 |
| DNA helicase activity | 0.17029946873911 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.123304946374679 | bayes_pls_golite062009 |
| mu-type opioid receptor binding | 0.105073376987609 | bayes_pls_golite062009 |
| opioid receptor binding | 0.105073376987609 | bayes_pls_golite062009 |
| minus-end-directed microtubule motor activity | 0.068779631341469 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0111338193708552 | bayes_pls_golite062009 |
|
Region A: Residues: [422-618] |
1 11 21 31 41 51
| | | | | |
1 GSELTKKTMS EGKTLEEANN INKSLMVLGY CISSLSDSKK RTGHIPYRDS QLTKLLADSL 60
61 AGNGVTLMIA CVSPAHYNHA ETLNTLRYAS RAKRIRTKPV IKMDPREALI LSLKRDIHAL 120
121 QMENDHLKAA LNLHHQAAPN GGPVENLLEL QLDRVSSGGG VPVPKVDLQR LPELDGSELA 180
181 ELVKLYMVEN ESLRQEN
|
| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 3kinB |
| Description: | KINESIN (DIMERIC) FROM RATTUS NORVEGICUS |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [619-676] |
1 11 21 31 41 51
| | | | | |
1 NHLFTVRETI LRDQEIVCRE NERLLKKLED VNKVCVRSPL IPARPAISPT TGKETPGT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [677-844] |
1 11 21 31 41 51
| | | | | |
1 EIWTNPEPLQ SPPGPDLPIE QRMSENANRR TDTAQKRIDQ KRIAKNILIM ANAFRKPDSD 60
61 ITKELNLNPE EAHAKQSTEF MPDSISIPAT TIGLAETAVL DIMAANLQQQ RSINLQLRRE 120
121 VEMERMPVSV ACSLMMKYML EHEEEDCLLS GFTQKVNPFR EKSSCSIL
|
| Detection Method: | |
| Confidence: | 4.221849 |
| Match: | 2iw5A |
| Description: | No description for 2iw5A was found. |
| Term | Confidence | Notes |
| transcription regulator activity | 3.3573497204506 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| DNA binding | 3.0205295442286 | bayes_pls_golite062009 |
| nucleic acid binding | 2.77547609431902 | bayes_pls_golite062009 |
| transcription factor activity | 2.57014522504183 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.38135384233451 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.1457670954804 | bayes_pls_golite062009 |
| actin binding | 2.03209305727522 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.94512319394414 | bayes_pls_golite062009 |
| protein binding | 1.88087411289001 | bayes_pls_golite062009 |
| transcription activator activity | 1.7593420956408 | bayes_pls_golite062009 |
| chromatin binding | 1.68308196781423 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.66519556937355 | bayes_pls_golite062009 |
| receptor activity | 1.16684800542624 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.10327547436113 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.06075239560835 | bayes_pls_golite062009 |
| signal transducer activity | 0.912169249499274 | bayes_pls_golite062009 |
| molecular transducer activity | 0.912169249499274 | bayes_pls_golite062009 |
| transcription repressor activity | 0.86319868225781 | bayes_pls_golite062009 |
| actin filament binding | 0.81690252782831 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 0.6697807021052 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 0.6697807021052 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.57338514991304 | bayes_pls_golite062009 |
| protein deacetylase activity | 0.47177024356295 | bayes_pls_golite062009 |
| transcription factor binding | 0.45727836611098 | bayes_pls_golite062009 |
| histone deacetylase activity | 0.426080122313218 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.0818464406491994 | bayes_pls_golite062009 |
| histone binding | 0.0391625783266718 | bayes_pls_golite062009 |
