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View Structure Prediction Details

Protein: PH4alphaSG2-PA
Organism: Drosophila melanogaster
Length: 527 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PH4alphaSG2-PA.

Description E-value Query
Range
Subject
Range
gi|50749316 - gi|50749316|ref|XP_421583.1| PREDICTED: similar to Prolyl 4-hydroxylase alpha-1 subunit (4-PH alpha-...
529.0 [0..1] [519..1]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDRHCLYIG IFQLIIWVGV ANGEFYSSVD SMQDLAQVEE ELLNATRSYV ESQQKQLDFY  60
   61 RRYVEQIKRE HEWATSQLKL DDYLGHPLHA FRLIKRLVRD WDSLIFEPIL ANNAREEFRA 120
  121 FVEVLSRDLG YPDQSELQGA IKGLARLQKV YNLATSDLAD GIIGGLNYGS D

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 61.065502
Match: PF08336.2
Description: No description for PF08336.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [172-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRWRECYEIG VQLFDLGEYQ RSLEWLQVAF ILLRNSPREE KDADHYLSDI REYASMANFE  60
   61 LGNPKKAARL LSQILESQPT HSAQQTQKYL ESRVPGKNVQ ETKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1tjcA
Description: Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
procollagen-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
procollagen-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 5.01373106146099 bayes_pls_golite062009
binding 2.09193012129784 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 0.534990536504941 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SWFSNYTRLC QGRRLPEERS GDPLRCYLDG KRHAYFTLAP LQVEPVHLDP DINVYHGMLS  60
   61 SKQILSIFEE ADKEEMVRSA VAGSGGEGTV RDLRVSQQTW LDYKSPVMNS VGRIIQFVSG 120
  121 FDMAGAEHMQ VANYGVGGQY EPHPDYFEVN LPKNFEGDRI STSMFYLSDV EQGGYTVFTK 180
  181 LNVFLPPVKG ALVMWHNLHR SLHVDARTLH AGCPVIVGSK RIGNIWMHSG YQEFRRPCNL 240
  241 TSDSYKSLAY RD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 2g19A
Description: No description for 2g19A was found.

YRC Informatics Platform - Version 3.0
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