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View Structure Prediction Details

Protein: sak1
Organism: Schizosaccharomyces pombe
Length: 766 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sak1.

Description E-value Query
Range
Subject
Range
gi|747966, gi|25... - gi|747966|gb|AAA67937.1| RFX family DNA-binding protein, gi|25463049|pir||T52535 suppressor of A-kin...
659.0 [0..1] [727..1]
gi|42554594, gi|... - gi|46126085|ref|XP_387596.1| hypothetical protein FG07420.1 [Gibberella zeae PH-1], gi|42554594|gb|E...
491.0 [0..4] [754..43]
gi|28922552, gi|... - gi|32413014|ref|XP_326987.1| hypothetical protein [Neurospora crassa], gi|28922552|gb|EAA31780.1| hy...
gi|85100705 - gi|85100705|ref|XP_961016.1| hypothetical protein [Neurospora crassa OR74A]
489.0 [0..16] [754..171]
gi|28949939 - gi|28949939|emb|CAD70925.1| related to cephalosporin C regulator 1 (cpcR1 gene) [Neurospora crassa]
489.0 [0..16] [754..191]
gi|109111677 - gi|109111677|ref|XP_001086140.1| PREDICTED: similar to regulatory factor X3 isoform b isoform 2 [Mac...
456.0 [0..333] [766..126]
gi|7406519 - gi|7406519|emb|CAB85587.1| cephalosporin C regulator 1 [Acremonium chrysogenum]
452.0 [0..6] [754..116]
gi|73946694 - gi|73946694|ref|XP_861094.1| PREDICTED: similar to regulatory factor X3 isoform b isoform 4 [Canis f...
445.0 [0..333] [766..276]
RFX3_MACFA - Transcription factor RFX3 OS=Macaca fascicularis GN=RFX3 PE=2 SV=1
442.0 [0..333] [766..301]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPSDLPGQI PLSRSDMNVQ DQLDPVQRFD THFMLPQEEN FLNRPSITSE SAHPRGSDLE  60
   61 QETELKRLAL EHEHYSLESL AEKL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [85-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RMDHVSANSE KFRQVFGICW LKRACEEQQD AAVQRNQIYA HYVEICNSLH IKPLNSASFG  60
   61 KLVRLLFPSI KTRRLGMRGH SKYHYCGIKL RG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.221849
Match: 1dp7P
Description: Class II MHC transcription factor RFX1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 4.84466441605416 bayes_pls_golite062009
nucleic acid binding 4.57954522145536 bayes_pls_golite062009
transcription factor activity 4.12685284895733 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
sequence-specific DNA binding 2.3918869755162 bayes_pls_golite062009
transcription activator activity 2.37668609508629 bayes_pls_golite062009
transcription repressor activity 2.22485867684613 bayes_pls_golite062009
protein binding 1.80415286835431 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.181186586600235 bayes_pls_golite062009
structural molecule activity 0.111941063082739 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.0360186926687502 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [177-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDSFRRLRTF SDSSLSPVSC SSFPKPIPNH FENDVSSIQN TNQRVESSPA SVNAAAIVRK  60
   61 SAVTPSSDPY NSPPPSIPLL GSQTNLQLAP SFAAPQAHPL PSHLSQSNVP PQLSHSSVPS 120
  121 PAPPRSVSQP TYFSQPMPQF SSSFVPGTSS IVPTLHPASA QEDFNLQHSL FFKLKLKFLP 180
  181 PHKLPWIPSL DVSSFSLPPI DYYLNGP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [384-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDNVEAKSAL MNIYSSHCIT LIESVRYMHL KQFLSEISNF PNSLSPSLLA LLSSPYFTKW  60
   61 IERSDTVMYR EILKLLFPMT LQVVPPPVLV LLRHLAENLV NHISSIYASH SSCLLQVKSE 120
  121 TAAIFSNLLS RLLRVNDTAH AAARFLANPA DRHLICNDWE RFVSTRFIVH RELMCNDKEA 180
  181 VAALDEWYSI LSTCSNPSEL LDPLKDKHEA SDTSMNRVEL RQIDGVLDRM ADFFLELPSR 240
  241 FPSC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [628-766]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPRMFLLCLG ALQTSVLREI TVSGGEAFGA LWVIRCWVDE YMTWVAEIGG YLDDSYDELE  60
   61 QHHANFHNKA GISQSNIPPH LQEHRQSQQH FQQDIEALQS QQQQQATKNS LMEAAYQNAQ 120
  121 KQKEDDYISI VFDTNGACS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle