YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC17A3.09c
Organism:	Schizosaccharomyces pombe
Length:	363 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC17A3.09c.

Description	E-value	Query Range	Subject Range
LPLA_SALTY - Lipoate-protein ligase A OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=lplA PE=... lcl\|NC_016856.1_... - [gene=lplA] [protein=lipoate-protein ligase A] [protein_id=YP_005240921.1] [location=complement(4844... gi\|197244278, gi... - gi\|197266023\|ref\|ZP_03166097.1\| lipoate-protein ligase A [Salmonella enterica subsp. enterica serova... LPLA_SALTY - Lipoate-protein ligase A OS=Salmonella typhimurium GN=lplA PE=3 SV=1 LPLA_SALTY - Lipoate-protein ligase A OS=Salmonella typhimurium GN=lplA PE=3 SV=1 gi\|167989818, gi... - gi\|205331409\|gb\|EDZ18173.1\| lipoate-protein ligase A [Salmonella enterica subsp. enterica serovar 4,... gi\|205336596, gi... - gi\|205336596\|gb\|EDZ23360.1\| lipoate-protein ligase A [Salmonella enterica subsp. enterica serovar He... LPLA_SALHS - Lipoate-protein ligase A OS=Salmonella heidelberg (strain SL476) GN=lplA PE=3 SV=1	328.0	[0..22]	[363..1]
gi\|25497293, gi\|... - pir\|\|C86138 probable lipoate-protein ligase A Z5988 [imported] - Escherichia coli (strain O157:H7, s... gi\|15804958, gi\|... - gi\|15804958\|ref\|NP_291000.1\| lipoate-protein ligase A [Escherichia coli O157:H7 EDL933], gi\|12519413... gi\|15834599, gi\|... - gi\|15834599\|ref\|NP_313372.1\| lipoate-protein ligase A [Escherichia coli O157:H7], gi\|13364823\|dbj\|BA... gi\|209160717, gi... - gi\|209399317\|ref\|YP_002273907.1\| protein smp precursor [Escherichia coli O157:H7 str. EC4115], gi\|20... gi\|254796382, gi... - gi\|254796382\|ref\|YP_003081219.1\| putative lipoate-protein ligase A [Escherichia coli O157:H7 str. TW... gi\|217320954, gi... - gi\|217324733\|ref\|ZP_03440817.1\| protein smp precursor [Escherichia coli O157:H7 str. TW14588], gi\|21... gi\|189405597, gi... - gi\|189405597\|ref\|ZP_02822967.2\| protein smp precursor [Escherichia coli O157:H7 str. EC508], gi\|1893... gi\|208807122, gi... - gi\|208807122\|ref\|ZP_03249459.1\| protein smp precursor [Escherichia coli O157:H7 str. EC4206], gi\|208... gi\|208733311, gi... - gi\|208812034\|ref\|ZP_03253363.1\| protein smp precursor [Escherichia coli O157:H7 str. EC4045], gi\|208... gi\|208739646, gi... - gi\|208819523\|ref\|ZP_03259843.1\| protein smp precursor [Escherichia coli O157:H7 str. EC4042], gi\|208... gi\|189356110, gi... - gi\|189402353\|ref\|ZP_02781813.2\| protein smp precursor [Escherichia coli O157:H7 str. EC4401], gi\|189... gi\|189363979, gi... - gi\|189402794\|ref\|ZP_02791676.2\| protein smp precursor [Escherichia coli O157:H7 str. EC4486], gi\|189... gi\|189367001, gi... - gi\|189404204\|ref\|ZP_02787747.2\| protein smp precursor [Escherichia coli O157:H7 str. EC4501], gi\|189... gi\|189374913, gi... - gi\|189404619\|ref\|ZP_02810038.2\| protein smp precursor [Escherichia coli O157:H7 str. EC869], gi\|1893... gi\|187767992, gi... - gi\|187776280\|ref\|ZP_02801641.2\| protein smp precursor [Escherichia coli O157:H7 str. EC4196], gi\|187... gi\|188025097, gi... - gi\|188025097\|ref\|ZP_02775997.2\| protein smp precursor [Escherichia coli O157:H7 str. EC4113], gi\|188... gi\|189010377, gi... - gi\|189010377\|ref\|ZP_02806684.2\| protein smp precursor [Escherichia coli O157:H7 str. EC4076], gi\|189... gi\|15834599, gi\|... - gi\|15834599\|ref\|NP_313372.1\| unknown domain/lipoate-protein ligase A fusion protein [Escherichia col...	325.0	[0..11]	[363..216]
LPLA_ECOUT - Lipoate-protein ligase A OS=Escherichia coli (strain UTI89 / UPEC) GN=lplA PE=3 SV=1 LPLA_ECOK1 - Lipoate-protein ligase A OS=Escherichia coli O1:K1 / APEC GN=lplA PE=3 SV=1	325.0	[0..22]	[363..1]
gi\|191167404, gi... - gi\|75229445\|ref\|ZP_00715995.1\| COG0095: Lipoate-protein ligase A [Escherichia coli B7A], gi\|19116740... LPLA_ECOHS - Lipoate-protein ligase A OS=Escherichia coli O9:H4 (strain HS) GN=lplA PE=3 SV=1	325.0	[0..22]	[363..1]
LPLA_ECOL5 - Lipoate-protein ligase A OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=lplA PE=3 SV=1 gi\|191173166, gi... - gi\|75239552\|ref\|ZP_00723522.1\| COG0095: Lipoate-protein ligase A [Escherichia coli F11], gi\|19117316...	324.0	[0..22]	[363..1]
gi\|194439301, gi... - gi\|83585293\|ref\|ZP_00923941.1\| COG0095: Lipoate-protein ligase A [Escherichia coli 101-1], gi\|194439... LPLA_SHISS - Lipoate-protein ligase A OS=Shigella sonnei (strain Ss046) GN=lplA PE=3 SV=1	324.0	[0..22]	[363..1]
LPLA_ECO57 - Lipoate-protein ligase A OS=Escherichia coli O157:H7 GN=lplA PE=3 SV=2 gi\|195937657 - gi\|195937657\|ref\|ZP_03083039.1\| lipoate-protein ligase A [Escherichia coli O157:H7 str. EC4024]	324.0	[0..22]	[363..1]
gi\|227837954, gi... - gi\|227885125\|ref\|ZP_04002930.1\| lipoate-protein ligase A [Escherichia coli 83972], gi\|227837954\|gb\|E... LPLA_ECOL6 - Lipoate-protein ligase A OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=lplA PE=3... LPLA_ECOL6 - Lipoate-protein ligase A OS=Escherichia coli O6 GN=lplA PE=3 SV=3	324.0	[0..22]	[363..1]
EG11796 - lipoate-protein ligase A / Lipoate-protein ligase A; selenolipoate resistant LPLA_ECOLI - Lipoate-protein ligase A (EC 6.3.2.-) - Escherichia coli LPLA_ECOBW - Lipoate-protein ligase A OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=lplA PE=3 SV=1 EG11796 - lipoate-protein ligase A / Lipoate-protein ligase A; selenolipoate resistant LPLA_ECODH - Lipoate-protein ligase A OS=Escherichia coli (strain K12 / DH10B) GN=lplA PE=3 SV=1 gi\|89111094, gi\|... - gi\|89111094\|ref\|AP_004874.1\| lipoate-protein ligase A [Escherichia coli str. K-12 substr. W3110], gi...	324.0	[0..22]	[363..1]
LPLA_SHIBS - Lipoate-protein ligase A OS=Shigella boydii serotype 4 (strain Sb227) GN=lplA PE=3 SV=1 LPLA_SHIB3 - Lipoate-protein ligase A OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=lplA PE=3 SV...	324.0	[0..22]	[363..1]

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Predicted Domain #1

Region A:
Residues: [1-363]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEAVTNPKS SLATFSKQLN GLLQAKVVVC KSVNPYFNLA LENYLYENST AKHCLLLYTN  60
   61 SPSVIIGRNQ NPWVEANVKL CRDNFVNIIR RKSGGGTVFH DFGNLNYSVL MNREEFSHTE 120
  121 NASIMIQALR NLGVHARLNQ RHDIVLAQSQ RKISGSAYKI SRNRCYHHGT MLLNSDLEGV 180
  181 REYLRSPSTG ILSKGVSSTR SPVSNTKLLK AEFIKQVISC FLLHKSHSTT TKPLSKPRAS 240
  241 SKRLYDIEPK SVITLEQNDL LGVPSILKAV NELQSWEWTF GQTPSFKQHL ESTELSVSMD 300
  301 ISVVHGRLEK VIFSTPNATL EHELSSIPWT GLCYESGFAN TFLISGIHSK EAISILKWIS 360
  361 DSI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.69897
Match:	1x2gA
Description:	Crystal Structure of Lipate-Protein Ligase A from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminoacyl-tRNA ligase activity	4.025601351766	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	4.02412423650651	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	4.02412423650651	bayes_pls_golite062009
ligase activity	3.51191116674556	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	0.685157827624735	bayes_pls_golite062009
binding	0.654061227819536	bayes_pls_golite062009
protein binding	0.380604392484225	bayes_pls_golite062009
catalytic activity	0.256292883613773	bayes_pls_golite062009
glycine-tRNA ligase activity	0.134313783036163	bayes_pls_golite062009
threonine-tRNA ligase activity	0.133891091298639	bayes_pls_golite062009
serine-tRNA ligase activity	0.0218173339521677	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: