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View Structure Prediction Details

Protein: lir-1
Organism: Caenorhabditis elegans
Length: 309 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lir-1.

Description E-value Query
Range
Subject
Range
gi|68365042 - gi|68365042|ref|XP_690837.1| PREDICTED: similar to zinc finger protein 135 (clone pHZ-17) [Danio rer...
415.0 [0..19] [308..57]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKFVVIELN DDAATIDLLS YCVKKNFERV SLLTRLEDHP YLRDDQDVVQ DDTQSQGTDG  60
   61 MLLQLNDEER QRLMKMISTP GPQTLSMERI QMAPGQGQHI LQQHQIPSTS SYTNNSFIYI 120
  121 KSDPQYKDEP QQQSNQFDAT VNSVAHGQAG LSTLEMFACN GSPNGGDVLR RKTPSRKAED 180
  181 SIKATCKVCG HDVMYS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.221849
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #2
Region A:
Residues: [197-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQRTWNLMRH VWIMHQSSKP NQCSICGYSH IKPYVRKHIE SQHKHDSNAT IIDLKSPELE  60
   61 AEWSQLLDQC FGVTYRKWKH HKEDTQHTVF AAGDEDYGHE HHFSPEEDVM TTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.09691
Match: 1x6hA
Description: Solution structures of the C2H2 type zinc finger domain of human Transcriptional repressor CTCF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.5693324142242 bayes_pls_golite062009
transcription regulator activity 1.20084827450202 bayes_pls_golite062009
DNA binding 1.11228868978256 bayes_pls_golite062009
nucleic acid binding 1.10067326005752 bayes_pls_golite062009
transcription factor activity 0.33874886911135 bayes_pls_golite062009
protein binding 0.186544761618633 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle