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Protein Overview: lir-1

General Information:
Name(s) found: lir-1 / CE27974 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00003044 locus:lir-1 status:Confirmed UniProt:G5EBR0 protein_id:CCD62036.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 309 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: molting cycle, protein-based cuticle [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKFVVIELN DDAATIDLLS YCVKKNFERV SLLTRLEDHP YLRDDQDVVQ DDTQSQGTDG  60
   61 MLLQLNDEER QRLMKMISTP GPQTLSMERI QMAPGQGQHI LQQHQIPSTS SYTNNSFIYI 120
  121 KSDPQYKDEP QQQSNQFDAT VNSVAHGQAG LSTLEMFACN GSPNGGDVLR RKTPSRKAED 180
  181 SIKATCKVCG HDVMYSPQRT WNLMRHVWIM HQSSKPNQCS ICGYSHIKPY VRKHIESQHK 240
  241 HDSNATIIDL KSPELEAEWS QLLDQCFGVT YRKWKHHKED TQHTVFAAGD EDYGHEHHFS 300
  301 PEEDVMTTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..196] PSI-BLAST 53.221849 No description for 2i13A was found.
    2 View Details [197..309] PSI-BLAST 8.09691 Solution structures of the C2H2 type zinc finger domain of human Transcriptional repressor CTCF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.5693324142242 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20084827450202 bayes_pls_golite062009
  • DNA binding
    		•  1.11228868978256 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.10067326005752 bayes_pls_golite062009
  • transcription factor activity
    		•  0.33874886911135 bayes_pls_golite062009
  • protein binding
    		•  0.186544761618633 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle