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View Structure Prediction Details

Protein: CE33612
Organism: Caenorhabditis elegans
Length: 394 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE33612.

Description E-value Query
Range
Subject
Range
gi|62128779, gi|... - gi|62181146|ref|YP_217563.1| ribonuclease III [Salmonella enterica subsp. enterica serovar Choleraes...
209.0 [0..55] [293..16]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRHVAQNLG SRNTSIQSYR LLRTRWERGY LKDLYHRRQI LGADPAISRS SYPNWDYDSE  60
   61 L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 2fflA
Description: Crystal Structure of Dicer from Giardia intestinalis
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [62-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAFGHRIGAP EISEDQYIKA LTNESFFQRA DVEENVESAQ PGAEVGTEHN AELVKRGEQN  60
   61 LSIWLKRYLR FHLAKAPEEL IEAIDSHLLD DECLAGIASH LGIDHLVRTK EFPISQESSA 120
  121 DAFRALAGVF SDEKVKNLVI DFIVPQLVDI DFADIYPLAD PLAVVTDLLK SNGVTEIEPR 180
  181 VLRSAGENSA EPIYVVAIYA DKLKNVGQSA GESLAIAVDM AAREALLRLW DITSEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.69897
Match: 1o0wA
Description: RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 3.36745043289731 bayes_pls_golite062009
structural molecule activity 3.14974722428281 bayes_pls_golite062009
RNA binding 1.99704120917168 bayes_pls_golite062009
binding 1.51260351901676 bayes_pls_golite062009
ribonuclease activity 1.08296225017277 bayes_pls_golite062009
nuclease activity 0.87617073306996 bayes_pls_golite062009
endonuclease activity 0.752043692857818 bayes_pls_golite062009
nucleic acid binding 0.46330171850662 bayes_pls_golite062009
protein binding 0.32114973384806 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.178480726843532 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [298-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLFFGDRAAN VPLERYSQPN FSLSQKCSPG TNTNIIDHSQ PVESPDNLIE AVLRYRNVVD  60
   61 AEVGKSYTKR LRHKFSRGSL AKRSFRYLVK PKPYTVA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.045757
Match: 2yt4A
Description: No description for 2yt4A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle