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View Structure Prediction Details

Protein: ARI10_ARATH
Organism: Arabidopsis thaliana
Length: 514 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARI10_ARATH.

Description E-value Query
Range
Subject
Range
ARI9_ARATH - Probable E3 ubiquitin-protein ligase ARI9 OS=Arabidopsis thaliana GN=ARI9 PE=2 SV=1
420.0 [0..1] [514..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYSDDDMID NESGEENNSD GGGNESYNYN AAVDTIILSE KSYVIIKEEE ILKLQRDDIE  60
   61 RVSTILFLSQ VEAIVLLLHY HWCVSKLEDE WFTDEERIRK TV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-200]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GILKEPVVDV NGTEVDIQCG ICFESYTRKE IASVSCGHPY CKTCWTGYIT TKIEDGPGCL  60
   61 RVKCPEPSCY AVVGQDMIDE VTEKKDKDKY YRYFLRSY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 2cklB
Description: No description for 2cklB was found.

Predicted Domain #3
Region A:
Residues: [201-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEDGKKMKWC PSPGCECAVE FGESSGYDVA CLCSYRFCWN CSEDAHSPVD CETVSKWIFK  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.61
Match: 2ct7A
Description: Solution Structure of the IBR domain of the RING finger protein 31 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.25982737281228 bayes_pls_golite062009
small conjugating protein ligase activity 5.16068345159314 bayes_pls_golite062009
acid-amino acid ligase activity 4.24782814163304 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.79292110382407 bayes_pls_golite062009
binding 2.70912934275371 bayes_pls_golite062009
protein binding 1.48593945455888 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.02238152139385 bayes_pls_golite062009
transcription regulator activity 0.911827807813353 bayes_pls_golite062009
ubiquitin-specific protease activity 0.821040441472875 bayes_pls_golite062009
transcription factor binding 0.769719546176331 bayes_pls_golite062009
nucleic acid binding 0.69956438716198 bayes_pls_golite062009
transcription repressor activity 0.451160479135532 bayes_pls_golite062009
ligase activity 0.424146907469434 bayes_pls_golite062009
DNA binding 0.369510087469936 bayes_pls_golite062009
cysteine-type peptidase activity 0.356312424125648 bayes_pls_golite062009
hydrolase activity 0.185228576891116 bayes_pls_golite062009
catalytic activity 0.168711389690753 bayes_pls_golite062009
peptidase activity 0.107857202210184 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.0136579100966835 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [261-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQDESENKNW ILANSKPCPK CKRPIEKSHG CNHMTCSASC GHRFCWICGK SYSDHYACNN  60
   61 YV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.045757
Match: 1wd2A
Description: Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.65442784325159 bayes_pls_golite062009
small conjugating protein ligase activity 5.55686022186257 bayes_pls_golite062009
acid-amino acid ligase activity 4.59153177011595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.07217714843839 bayes_pls_golite062009
binding 2.78710909602478 bayes_pls_golite062009
protein binding 1.5975811408548 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
transcription regulator activity 0.943706743211193 bayes_pls_golite062009
transcription factor binding 0.90065892745057 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
transcription repressor activity 0.517687629465752 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
DNA binding 0.365874679056682 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
hydrolase activity 0.156835837705934 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
peptidase activity 0.121357659741468 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [323-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDADHDKRTL LQSEIKRYTH YYVRWVENQS SRLKAMSDLE KFQSVQLKQL SDNQCKPKID  60
   61 LQFIVDAWLQ IIECRRVLKW TYAYGYYLDN LAKRPLFEYL QGEAETGLER LHHCAENELK 120
  121 QFFIKSEDPS DTFNAFRMKL TGLTKVTKTY FDNLVKALEN GLADVTKSSE ESADFLETQK 180
  181 LYDAYISEGC FF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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