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View Structure Prediction Details

Protein: gi|151941602
Organism: Saccharomyces cerevisiae YJM789
Length: 328 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|151941602.

Description E-value Query
Range
Subject
Range
gi|1174562, gi|6... - gi|607956|gb|AAA62664.1| transcription factor TFIIE, small subunit, gi|1174562|sp|P36145.2|T2EB_YEAS...
0.0 [1..328] [1..328]
T2EB_SCHPO - Transcription initiation factor IIE subunit beta OS=Schizosaccharomyces pombe (strain 972 / ATCC 248...
tfa2 - transcription factor TFIIE beta subunit Tfa2
9.0E-92 [62..325] [15..281]
gi|1834288 - gi|1834288|dbj|BAA19123.1| S.pombe TFA2 homolog [Schizosaccharomyces pombe]
5.0E-78 [109..325] [1..220]
CE26813 - transcription intiation factor TFIIE-BETA status:Confirmed UniProt:Q20776 protein_id:CAA91336.2
1.0E-76 [47..324] [7..288]
gi|157071405, gi... - gi|164426610|ref|XP_957548.2| hypothetical protein NCU03909 [Neurospora crassa OR74A], gi|157071405|...
gi|16945428 - gi|16945428|emb|CAB91686.2| related to transcription initiation factor IIE, beta subunit [Neurospora...
2.0E-74 [50..326] [3..299]
GTF2E2 - general transcription factor IIE, polypeptide 2, beta 34kDa
gi|55630478, gi|... - gi|55630478|ref|XP_519695.1| PREDICTED: general transcription factor IIE, polypeptide 2, beta 34kDa ...
gi|208966362 - gi|208966362|dbj|BAG73195.1| general transcription factor IIE, polypeptide 2, beta 34kDa [synthetic ...
8.0E-66 [47..325] [7..285]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
2.0E-65 [47..325] [7..285]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKNRDPLLA NLNAFKSKVK SAPVIAPAKV GQKKTNDTVI TIDGNTRKRT ASERAQENTL  60
   61 NSAKNPVLVD IKKEAGSNSS NAISLDDDDD DEDFGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSKKVRPGS IAAAALQANQ TDISKSHDSS KLLWATEYIQ KKGKPVLVNE LLDYLSMKKD  60
   61 DKVIELLKKL DRIEFDPKKG TFKYLSTYDV H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 1d8jA_
Description: The central core domain of TFIIE beta
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 5.67074370996647 bayes_pls_golite062009
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 4.84466441605416 bayes_pls_golite062009
nucleic acid binding 4.57954522145536 bayes_pls_golite062009
transcription factor activity 4.12685284895733 bayes_pls_golite062009
binding 4.05190810999633 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
sequence-specific DNA binding 2.3918869755162 bayes_pls_golite062009
transcription activator activity 2.37668609508629 bayes_pls_golite062009
transcription repressor activity 2.22485867684613 bayes_pls_golite062009
DNA-directed RNA polymerase activity 1.82365519759474 bayes_pls_golite062009
RNA polymerase activity 1.82365519759474 bayes_pls_golite062009
protein binding 0.961087148890615 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
nucleotidyltransferase activity 0.237727660028553 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.157471576785569 bayes_pls_golite062009
hydrolase activity 0.140191206949582 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.0360186926687502 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [188-328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSELLKLLR SQVTFKGISC KDLKDGWPQC DETINQLEED SKILVLRTKK DKTPRYVWYN  60
   61 SGGNLKCIDE EFVKMWENVQ LPQFAELPRK LQDLGLKPAS VDPATIKRQT KRVEVKKKRQ 120
  121 RKGKITNTHM TGILKDYSHR V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle