YRC Public Data Repository - Protein Structure Prediction

Protein:	METQ_SALTI
Organism:	Salmonella typhi
Length:	271 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for METQ_SALTI.

Description	E-value	Query Range	Subject Range
gi\|74474895 - gi\|74474895\|dbj\|BAE44432.1\| antigenic protein Et 28 [Edwardsiella tarda]	9.0E-64	[1..271]	[1..271]
gi\|56126775, gi\|... - gi\|56412518\|ref\|YP_149593.1\| DL-methionine transporter substrate-binding subunit [Salmonella enteric... gi\|197361453, gi... - gi\|197361453\|ref\|YP_002141089.1\| DL-methionine transporter substrate-binding subunit [Salmonella ent...	9.0E-64	[1..271]	[1..271]
METQ_SALTY - D-methionine-binding lipoprotein metQ OS=Salmonella typhimurium GN=metQ PE=3 SV=1 gi\|224466619, gi... - gi\|224582092\|ref\|YP_002635890.1\| putative lipoprotein precursor [Salmonella enterica subsp. enterica... gi\|204927300, gi... - gi\|204927300\|ref\|ZP_03218502.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipop... gi\|199604040, gi... - gi\|200386942\|ref\|ZP_03213554.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipop... gi\|207855763, gi... - gi\|207855763\|ref\|YP_002242414.1\| DL-methionine transporter substrate-binding subunit [Salmonella ent... gi\|205271363, gi... - gi\|205351582\|ref\|YP_002225383.1\| DL-methionine transporter substrate-binding subunit [Salmonella ent... gi\|62178814, gi\|... - gi\|62178814\|ref\|YP_215231.1\| DL-methionine transporter substrate-binding subunit [Salmonella enteric... METQ_SALTY - D-methionine-binding lipoprotein MetQ OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720... gi\|197213623, gi... - gi\|197249920\|ref\|YP_002145250.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipo... gi\|194736374, gi... - gi\|194736374\|ref\|YP_002113268.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipo... gi\|197940543, gi... - gi\|198246027\|ref\|YP_002214206.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipo... gi\|197240061, gi... - gi\|197261806\|ref\|ZP_03161880.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipop... gi\|194444076, gi... - gi\|194444076\|ref\|YP_002039485.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipo... gi\|168823083, gi... - gi\|205340616\|gb\|EDZ27380.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote... gi\|194469222, gi... - gi\|194469222\|ref\|ZP_03075206.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipop... gi\|194408651, gi... - gi\|194450347\|ref\|YP_002044235.1\| DL-methionine transporter substrate-binding subunit [Salmonella ent... gi\|238911311 - gi\|238911311\|ref\|ZP_04655148.1\| DL-methionine transporter substrate-binding subunit [Salmonella ente... lcl\|NC_016856.1_... - [gene=metQ] [protein=DL-methionine transporter substrate-binding subunit] [protein_id=YP_005235916.1... gi\|205336226, gi... - gi\|205336226\|gb\|EDZ22990.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote... gi\|197291660, gi... - gi\|197291660\|gb\|EDY31010.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote... gi\|195632682, gi... - gi\|195632682\|gb\|EDX51136.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote... gi\|205346915, gi... - gi\|205346915\|gb\|EDZ33546.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote... METQ_SALTY - D-methionine-binding lipoprotein metQ OS=Salmonella typhimurium GN=metQ PE=3 SV=1 gi\|167553339, gi... - gi\|205322180\|gb\|EDZ10019.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote... gi\|161361984, gi... - gi\|161612620\|ref\|YP_001586585.1\| DL-methionine transporter substrate-binding subunit [Salmonella ent... gi\|205335212, gi... - gi\|205335212\|gb\|EDZ21976.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote... gi\|205331324, gi... - gi\|205331324\|gb\|EDZ18088.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipoprote...	2.0E-63	[1..271]	[1..271]
gi\|77977719, gi\|... - gi\|77977719\|ref\|ZP_00833160.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s...	2.0E-62	[1..271]	[1..271]
gi\|238784907, gi... - gi\|77957717\|ref\|ZP_00821766.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s...	2.0E-62	[1..271]	[1..271]
gi\|30039996, gi\|... - gi\|30061754\|ref\|NP_835925.1\| DL-methionine transporter substrate-binding subunit [Shigella flexneri ... gi\|24050404, gi\|... - gi\|24111633\|ref\|NP_706143.1\| DL-methionine transporter substrate-binding subunit [Shigella flexneri ... gi\|193067670, gi... - gi\|75238902\|ref\|ZP_00722884.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|193063224, gi... - gi\|75258809\|ref\|ZP_00730199.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|75210522, gi\|... - gi\|75210522\|ref\|ZP_00710673.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|209910649, gi... - gi\|209917390\|ref\|YP_002291474.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... gi\|254160317, gi... - gi\|254160317\|ref\|YP_003043425.1\| DL-methionine transporter subunit [Escherichia coli B str. REL606],... gi\|190902909, gi... - gi\|75229817\|ref\|ZP_00716344.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|218552778, gi... - gi\|218552778\|ref\|YP_002385691.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... gi\|253325819, gi... - gi\|254287120\|ref\|YP_003052868.1\| DL-methionine transporter subunit [Escherichia coli BL21(DE3)], gi\|... gi\|218350395, gi... - gi\|218693663\|ref\|YP_002401330.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... gi\|251783756, gi... - gi\|251783756\|ref\|YP_002998060.1\| hypothetical protein B21_00195 [Escherichia coli BL21], gi\|24237602... gi\|218703452, gi... - gi\|218703452\|ref\|YP_002410971.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... gi\|73854295, gi\|... - gi\|74310818\|ref\|YP_309237.1\| DL-methionine transporter substrate-binding subunit [Shigella sonnei Ss... gi\|82542796, gi\|... - gi\|82542796\|ref\|YP_406743.1\| DL-methionine transporter substrate-binding subunit [Shigella boydii Sb... gi\|110804249, gi... - gi\|110804249\|ref\|YP_687769.1\| DL-methionine transporter substrate-binding subunit [Shigella flexneri... gi\|75189295, gi\|... - gi\|75189295\|ref\|ZP_00702562.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|157159664, gi... - gi\|75194409\|ref\|ZP_00704479.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|194421150, gi... - gi\|83584735\|ref\|ZP_00923399.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|187733230, gi... - gi\|75176457\|ref\|ZP_00696594.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s...	2.0E-62	[1..271]	[1..271]
gi\|169756377, gi... - gi\|170021449\|ref\|YP_001726403.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... EG11504 - DL-methionine transporter subunit / Periplasmic methionine binding lipoprotein; methionine sulfoximi... gi\|227884889, gi... - gi\|227884889\|ref\|ZP_04002694.1\| DL-methionine transporter substrate-binding subunit [Escherichia col... gi\|194435012, gi... - gi\|83568974\|ref\|ZP_00920438.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|226902269, gi... - gi\|237704357\|ref\|ZP_04534838.1\| DL-methionine transporter subunit [Escherichia sp. 3_2_53FAA], gi\|22... gi\|190908269, gi... - gi\|75241736\|ref\|ZP_00725573.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|238860784, gi... - gi\|238899596\|ref\|YP_002925392.1\| DL-methionine transporter subunit [Escherichia coli BW2952], gi\|238... METQ_ECOLI - D-methionine-binding lipoprotein metQ precursor - Escherichia coli gi\|188488864, gi... - gi\|75512211\|ref\|ZP_00734783.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|254037617, gi... - gi\|254037617\|ref\|ZP_04871694.1\| D-methionine ABC transporter [Escherichia sp. 1_1_43], gi\|226840723\|... EG11504 - DL-methionine transporter subunit / Periplasmic methionine binding lipoprotein; methionine sulfoximi... gi\|4902940, gi\|8... - gi\|89107078\|ref\|AP_000858.1\| DL-methionine transporter subunit [Escherichia coli str. K-12 substr. W... gi\|170680927, gi... - gi\|170680927\|ref\|YP_001742326.1\| D-methionine ABC transporter, periplasmic D-methionine-binding lipo... gi\|170079834, gi... - gi\|170079834\|ref\|YP_001729154.1\| receptor component of DL-methionine uptake transporter (MUT) [Esche... gi\|218355194, gi... - gi\|218547653\|ref\|YP_002381444.1\| DL-methionine transporter substrate-binding subunit [Escherichia fe... gi\|215263431, gi... - gi\|215485359\|ref\|YP_002327790.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... gi\|91209268, gi\|... - gi\|91209268\|ref\|YP_539254.1\| DL-methionine transporter substrate-binding subunit [Escherichia coli U... gi\|218425637, gi... - gi\|218688073\|ref\|YP_002396285.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... gi\|110342010, gi... - gi\|110640418\|ref\|YP_668146.1\| DL-methionine transporter substrate-binding subunit [Escherichia coli ... gi\|218363908, gi... - gi\|218557139\|ref\|YP_002390052.1\| DL-methionine transporter substrate-binding subunit [Escherichia co... gi\|115511606, gi... - gi\|117622482\|ref\|YP_851395.1\| DL-methionine transporter substrate-binding subunit [Escherichia coli ... gi\|124499734, gi... - gi\|124529578\|ref\|ZP_01700522.1\| lipoprotein, YaeC family [Escherichia coli B], gi\|124499734\|gb\|EAY47... gi\|218698850, gi... - gi\|218698850\|ref\|YP_002406479.1\| DL-methionine transporter substrate-binding subunit [Escherichia co...	3.0E-62	[1..271]	[1..271]
gi\|238787206, gi... - gi\|77972740\|ref\|ZP_00828299.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s...	3.0E-62	[1..271]	[1..271]
gi\|36784121, gi\|... - gi\|37524696\|ref\|NP_928040.1\| DL-methionine transporter substrate-binding subunit [Photorhabdus lumin...	4.0E-62	[1..271]	[1..271]
gi\|149290541, gi... - gi\|149366927\|ref\|ZP_01888960.1\| putative lipoprotein [Yersinia pestis CA88-4125], gi\|149290541\|gb\|ED... gi\|229837779, gi... - gi\|229837779\|ref\|ZP_04457939.1\| putative lipoprotein [Yersinia pestis Pestoides A], gi\|229704156\|gb\|... gi\|145210618, gi... - gi\|145598922\|ref\|YP_001162998.1\| DL-methionine transporter substrate-binding subunit [Yersinia pesti... gi\|229841001, gi... - gi\|229841001\|ref\|ZP_04461160.1\| putative lipoprotein [Yersinia pestis biovar Orientalis str. PEXU2],... gi\|229843102, gi... - gi\|229843102\|ref\|ZP_04463252.1\| putative lipoprotein [Yersinia pestis biovar Orientalis str. India 1... gi\|165921021, gi... - gi\|165927125\|ref\|ZP_02222957.1\| D-methionine ABC transporter, periplasmic D-methionine-binding prote... METQ_YERPE - D-methionine-binding lipoprotein MetQ OS=Yersinia pestis GN=metQ PE=3 SV=1 gi\|45442546, gi\|... - gi\|45442546\|ref\|NP_994085.1\| DL-methionine transporter substrate-binding subunit [Yersinia pestis bi... gi\|21960026, gi\|... - gi\|22126982\|ref\|NP_670405.1\| DL-methionine transporter substrate-binding subunit [Yersinia pestis KI... gi\|218928240, gi... - gi\|218928240\|ref\|YP_002346115.1\| DL-methionine transporter substrate-binding subunit [Yersinia pesti... gi\|77633966, gi\|... - gi\|77633966\|ref\|ZP_00796078.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|108776736, gi... - gi\|229903531\|ref\|ZP_04518644.1\| putative lipoprotein [Yersinia pestis Nepal516], gi\|229679301\|gb\|EEO... gi\|166211644, gi... - gi\|166211644\|ref\|ZP_02237679.1\| D-methionine ABC transporter, periplasmic D-methionine-binding prote... gi\|166011933, gi... - gi\|166011933\|ref\|ZP_02232831.1\| D-methionine ABC transporter, periplasmic D-methionine-binding prote... gi\|167419837, gi... - gi\|167419837\|ref\|ZP_02311590.1\| D-methionine ABC transporter, periplasmic D-methionine-binding prote... gi\|167050758, gi... - gi\|167400050\|ref\|ZP_02305568.1\| D-methionine ABC transporter, periplasmic D-methionine-binding prote... gi\|167470136 - gi\|167470136\|ref\|ZP_02334840.1\| D-methionine ABC transporter, periplasmic D-methionine-binding prote... gi\|167055668, gi... - gi\|167425268\|ref\|ZP_02317021.1\| D-methionine ABC transporter, periplasmic D-methionine-binding prote... gi\|165912227, gi... - gi\|89105162\|ref\|ZP_01177687.1\| COG1464: ABC-type metal ion transport system, periplasmic component/s... gi\|108806545, gi... - gi\|108806545\|ref\|YP_650461.1\| DL-methionine transporter substrate-binding subunit [Yersinia pestis A...	4.0E-62	[1..271]	[1..271]

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Predicted Domain #1

Region A:
Residues: [1-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFKFKTFAA VGALIGSLAL AGCGQDEKDP NHIKVGVIVG AEQQVAEVAQ KVAKEKYGLD  60
   61 VELVTFNDYV LPNEALSKGD IDANAFQHKP YLDQQIKDRG YKLVSVGKTF VYPIAGYSKK 120
  121 IKSLDELKDG SQVAVPNDPT NLGRSLLLLQ KVGLIKLKDG VSLLPTSLDI VENPKNLKIV 180
  181 ELEAPQLPRS LDDAQIALAV INTTYASQIG LTPAKDGIFV EDKDSPYVNL IVTREDNKDA 240
  241 ENVKKFVQAY QSDEVYEAAN KVFNGGAVKG W

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.69897
Match:	1xs5A
Description:	The Crystal Structure of Lipoprotein Tp32 from Treponema pallidum
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	3.92658561501282	bayes_pls_golite062009
transmembrane transporter activity	3.71430307970333	bayes_pls_golite062009
amine transmembrane transporter activity	3.68263102620434	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	3.45855021324499	bayes_pls_golite062009
organic acid transmembrane transporter activity	3.44437031517765	bayes_pls_golite062009
substrate-specific transporter activity	3.34421502810243	bayes_pls_golite062009
primary active transmembrane transporter activity	3.33883206510679	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	3.33572158012752	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	3.31947078781945	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	3.3164655425684	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	3.3159417475856	bayes_pls_golite062009
active transmembrane transporter activity	3.25041295044206	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.76254706952599	bayes_pls_golite062009
ATPase activity, coupled	2.65558937563899	bayes_pls_golite062009
amino acid transmembrane transporter activity	2.47628874886983	bayes_pls_golite062009
amine binding	2.4097403582482	bayes_pls_golite062009
ATPase activity	2.40029628345531	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.3103850882599	bayes_pls_golite062009
pyrophosphatase activity	2.2348608319417	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.21542452486366	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.21260159167253	bayes_pls_golite062009
sulfur amino acid transmembrane transporter activity	2.14594454285001	bayes_pls_golite062009
ion transmembrane transporter activity	1.84929214408108	bayes_pls_golite062009
D-methionine transmembrane transporter activity	1.72463508462925	bayes_pls_golite062009
methionine transmembrane transporter activity	1.72463508462925	bayes_pls_golite062009
amino acid-transporting ATPase activity	1.65232476690022	bayes_pls_golite062009
amine-transporting ATPase activity	1.59812090922796	bayes_pls_golite062009
binding	1.54172013140566	bayes_pls_golite062009
amino acid binding	1.18820874048991	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.88623763826001	bayes_pls_golite062009
hydrolase activity	0.825775589802563	bayes_pls_golite062009
anion transmembrane transporter activity	0.75669016367838	bayes_pls_golite062009
polyamine transmembrane transporter activity	0.621740283439039	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	0.555351218220589	bayes_pls_golite062009
polyamine-transporting ATPase activity	0.436507323554782	bayes_pls_golite062009
cation transmembrane transporter activity	0.343508026849565	bayes_pls_golite062009
L-amino acid transmembrane transporter activity	0.29299124929094	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	0.149393758153546	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0237973852493387	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: